CN101228875B - Active compound combination - Google Patents
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- CN101228875B CN101228875B CN2008100082307A CN200810008230A CN101228875B CN 101228875 B CN101228875 B CN 101228875B CN 2008100082307 A CN2008100082307 A CN 2008100082307A CN 200810008230 A CN200810008230 A CN 200810008230A CN 101228875 B CN101228875 B CN 101228875B
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- WLPCAERCXQSYLQ-UHFFFAOYSA-N N#Cc1ccccc1NC(c([s]nc1Cl)c1Cl)=O Chemical compound N#Cc1ccccc1NC(c([s]nc1Cl)c1Cl)=O WLPCAERCXQSYLQ-UHFFFAOYSA-N 0.000 description 1
Abstract
The invention relates to an active compound conjugate, which consists of a compound (A) of formula (I) and another pest-killing or antibacterial active compound (B) selected from Metominostrobin, thifluzamide and thiacloprid. Besides, the invention relates to a method for curing or preventing the plant fungals of plants or crops, relates to the seed treatment usage of the conjugate in the invention and relates to a seed protection method and the seeds after treatment.
Description
The present invention relates to a kind of active agent combinations, the composition of particularly a kind of sterilization and desinsection, this bond contain the compound (A) (2 ' cyano group-3,4-two chloroisothiazoles-5-formailide, general different metsulfovax (isotianil) by name) of formula (I)
Be selected from the sterilization of SSF 126 (metominostrobin) (CAS 133408-50-1), thiophene fluorine bacterium amine (thifluzamide) (CAS 130000-40-7) and thiophene worm quinoline (thiacloprid) (CAS 111988-49-9) or the reactive compound (B) of desinsection with another kind.
In addition; the invention still further relates to a kind of being used for the treatment of property or prophylactically prevent and treat the phytopathogenic fungi of plant or crop and/or the method for microorganism and/or insect; relate to the purposes that bond of the present invention is used to handle seed, relate to and a kind ofly be used to protect the method for seed and relate to the seed of handling.
Known (A) 3,4-two chloro-N-(2-cyano-phenyl)-5-isothiazole formamide has sterilization and insecticidal properties.In addition, also find the invasion and attack (US-A 5 240 951 and JP-A 06-009 313) that Isothiazolcarboxylicacid acid derivatives is very suitable for protective plant and avoids noxious plant pathomycete and microorganism.Compound of the present invention (A) both had been suitable for transferring the defence of plant to noxious plant pathomycete and microbiological attack, also can be used as microbicide and was used for directly preventing and treating phytopathogenic fungi and microorganism.In addition, compound (A) also has activity (WO-A 99/24414) to the insect of destroying plant.This material has excellent activity; But it is unsatisfactory sometimes under low rate of application.
In addition, the chemical compound lot of the methoxy acrylic (strobilurin) under the known SSF 126 can be used for preventing and treating fungi (agricultural chemicals handbook (Pesticide Manual), the 14th edition (2006), No.569).Thiophene fluorine bacterium amine can be used for preventing and treating fungi (the agricultural chemicals handbook, the 14th edition (2006), No.816).Also known thiophene worm quinoline is a kind of anabasine (neonicotinylic) compound, can be used for preventing and treating insect (Pesticide Manual, the 14th edition (2006), the No.811 of plant and crop; Modern agricultural chemicals (" Modern Agrochemicals "), the 4th volume, No.3, in June, 2005).But the activity of these materials is always not enough equally when hanging down rate of application.
And, because the environment and the economic requirement of modern bactericide improved constantly, for example, for the requirement of the formation of action spectrum, toxicity, selectivity, rate of application, residue and good preparative capacibility aspect; And owing to also there is the problem that for example the known activity compound is produced resistance, therefore, develop that new to have the bactericide and the insecticide that are better than its known homologue at least in some aspects be a long-range mission.
The invention provides the active agent combinations/composition that reaches described target at least in some aspects.
Surprisingly, have now found that, the additive property that bond of the present invention has not only produced control phytopathogenic fungi and/or microorganism and/or insect action spectrum improves, and has reached the synergistic effect of magnify a compound (A) and compound (B) sphere of action with following dual mode.At first, under the same good situation of action effect maintenance, reduced the rate of application of compound (A) and compound (B).Next, even in the invalid fully low rate of application scope of these two individualized compounds, this bond still can reach high phytopathogen and prevent effect.On the one hand, this has significantly widened the scope of the phytopathogen that can prevent and treat, and has increased the safety of using on the other hand.
Yet except the certain synergy aspect sterilization and/or insecticidal activity, Pesticidal combinations of the present invention also has other surprising advantageous feature, and these advantageous feature also can be described as synergistic activity.Sterilization that the example of the described advantageous feature that can mention is: widened other phytopathogenic fungi and/or microorganism and/or insect---for example antagonism strain (resistantstrain)---and/or insecticidal activity spectrum; Reduced the rate of application of active component; Even under the invalid fully rate of application of individualized compound, reach sufficient control of insect by the present composition; During preparation or the advantageous property when using, for example in grinding, screening, emulsification, dissolving or divide timing; The storage stability that improves; Improved photostability; More favourable degradability; Improved toxicity performance or ecological toxicity performance; The performance of improved useful plant comprises: rudiment (emergence), crop yield, more flourishing root system, tiller that (tillering) increases, plant height increases, blade is bigger, the basal leaf lethality is littler, it is stronger to tiller,, the required fertilizer of leaf look greener still less, required seed still less, tiller more voluminous (productive), bloom more early, kernel maturity early, plant still less lodges (verse, lodginig), shoot growth improves, the plant growing way is improved and rudiment more early; Any other advantage perhaps well known to those skilled in the art.
Bond of the present invention also can provide the interior absorption (systemicity) of improvement to used reactive compound.In fact, even some used Fungicidal compounds do not have any interior absorption or gratifying interior absorption, these compounds in the present composition still can show such characteristic.
Similarly, bond of the present invention can make the sterilization drug effect continuation of the reactive compound of being used improve.
Another advantage of bond of the present invention is the drug effect that can obtain to improve.
Therefore, the invention provides a kind of bond, this bond contains:
The compound (A) of formula (I)
Be selected from the desinsection of SSF 126, thiophene fluorine bacterium amine and thiophene worm quinoline or the reactive compound (B) of sterilization with another kind.
The bond that preferably contains formula (I) compound (A) and SSF 126.
The bond that preferably contains formula (I) compound (A) and thiophene fluorine bacterium amine.
The bond that preferably contains formula (I) compound (A) and thiophene worm quinoline.
If the reactive compound in the active agent combinations of the present invention exists with certain weight ratio, then synergistic effect is remarkable especially.But the weight ratio of the reactive compound in this active agent combinations can change in wide in range relatively scope.Usually, compound in the bond of the present invention (A) and weight ratio (A) (B): (B) have 625 of synergistic effect: 1-1: in 625 scopes, preferred weight ratio is 500: 1-1: 500, and more preferably weight ratio is 250: 1-1: 250.(A) that the present invention can use: other ratio (B) is: 100: 1-1: 100,150: 1-1: 150,200: 1-1: 200,90: 1-1: 90,80: 1-1: 80,70: 1-1: 70,60: 1-1: 60,40: 1-1: 40,30: 1-1: 30,10: 1-1: 10,5: 1-1: 5,4: 1-1: 4,3: 1-1: 3, and these ratios are by providing the preferred property enhancing of order.
When compound (A) or compound (B) can tautomeric form exist, described compound was interpreted as also comprising corresponding tautomeric form under situation about being suitable in context, even they are not specifically mentioned respectively.
Have the compound (A) of at least one basic center or compound (B) and can form for example acid addition salt with for example following various acid: with strong inorganic acid, as inorganic acid, for example perchloric acid, sulfuric acid, nitric acid, nitrous acid, phosphoric acid or halogen acids; With strong organic carboxyl acid, as (for example halo) C that does not replace or replace
1-C
4Alkanecarboxylic acid (for example acetate), saturated or unsaturated dicarboxylic acids is ethanedioic acid, malonic acid, succinic acid, cis-1, fumaric acid and phthalic acid for example, and hydroxycarboxylic acid is ascorbic acid, lactic acid, malic acid, tartaric acid, citric acid or benzoic acid for example; Or and organic sulfonic acid, as (for example halo) C unsubstituted or that replace
1-C
4Alkane sulfonic acid or aryl sulfonic acid, for example methanesulfonic acid or p-methyl benzenesulfonic acid.Compound (A) or compound (B) with at least one acidic group can for example form for example salt with alkali---as slaine, and for example alkali metal salt or alkali salt, for example sodium salt, sylvite or magnesium salts; Perhaps with ammonia or Organic Amines such as morpholine, piperidines, pyrrolidines, single low alkyl group amine, two low alkyl group amine or three low alkyl group amine (for example ethamine, diethylamine, triethylamine or dimethyl propyl amine) or the low alkyl group amine of monohydroxy, the low alkyl group amine of two hydroxyl or the low alkyl group amine (for example MEA, diethanol amine or triethanolamine) of trihydroxy---form salt.In addition, can choose the corresponding inner salt of formation wantonly.In the present invention, preferably favourable salt to agrochemicals.In view of the free form of compound (A) or compound (B) and the close relation between its salt form, under suitable and favourable situation, mentioned any free cpds (A) or free cpds (B) or their salt are interpreted as also comprising respectively corresponding salt or free cpds (A) or free cpds (B) in the context.This equally also is applicable to the dynamic isomer and the salt thereof of compound (A) or compound (B).
The various combination of the word among the present invention " combination " expression compound (A) and compound (B), for example combination of following form: with single " promptly mixed " form; With the form of the merging spray liquid of each independent preparation of containing each single-activity compound, for example " bucket mixes "; And with the merging type of service of each active ingredient, wherein each active ingredient in a continuous manner, promptly for example use in several hours or several days in the rationally short time one by one.Preferably, compound (A) is not that enforcement is of the present invention necessary with the order of administration of compound (B).
All organisms that word among the present invention " pathogene " expression damages plant or any plant parts.
All fungi organisms and pipe hair biologic artifact (chromista organism) represented in word among the present invention " fungi ".
All fungi organisms and a pipe hair biologic artifact that word among the present invention " phytopathogenic fungi " expression damages plant or any plant parts.Classification of fungi group's example has sac fungi (Ascomycota), basidiomycetes (Basidiomycota), chytrid (Chytridiomycota), imperfect fungi (Deuteromycota), polymerization bacterium (Glomeromycota), microsporidian (Microsporidia), zygomycete (Zygomycota) and imperfect fungus (anamorphic fungi).The biological example of pipe hair is oomycetes (Oomycota).
All bacterium organisms and protozoa organism represented in word among the present invention " microorganism ".Example is plasmodiophora brassicae (Plasmodiophoromycetes).
All viruses that word among the present invention " virus " expression damages plant or any plant parts.Example is DNA-, RNA and DNA and RNA retrovirus and subviral agent.
All aschelminths (aschelminthes) organism and general arthropods (panarthropoda) organism that word among the present invention " insect " expression damages plant or any plant parts.Example is Nematoda (Nematoda), Arthropoda (Arthopoda), Hexapoda (Hexapoda) and arachnids (Arachnida).
Word among the present invention " insecticide " expression has opposing harmful insect class, mite class or nematoda or reduces the compound of insect to the activity of plant or plant parts destruction.
Reactive compound in the present composition has effective microbiocidal activity and can be used for preventing and treating harmful phytopathogenic fungi and/or microorganism and/or insect in crop protection or the protection at material.
Fungicidal compounds in the present composition can be used on and is used to prevent and treat phytopathogenic fungi and/or microorganism in the crop protection, for example plasmodiophora brassicae, oomycetes, chytrid, zygomycete, sac fungi, basidiomycetes and imperfect fungus (Deuteromycota).
Bacterium compound extremely in the present composition can be used to prevent and treat microorganism in crop protection, for example pseudomonas (Pseudomonadaceae), rhizobium (Rhizobiaceae), enterobacteria (Enterobacteriaceae), excellent bacillus (Corynebacteriaceae) and streptomycete (Streptomycetaceae).
Pesticide compound in the present composition can be used for pest control in crop protection, for example Lepidoptera (Lepidoptera).
Sterilization of the present invention and/or desinsection bond and/or composition can be used for therapeutic or prophylactically prevent and treat phytopathogenic fungi and/or microorganism and/or the insect of plant or crop.Therefore, another aspect of the present invention, a kind of therapeutic is provided or has has prophylactically prevented and treated the phytopathogenic fungi of plant or crop and/or the method for microorganism and/or insect, this method comprises bactericide of the present invention and/or insecticides is applied to the soil that seed, plant or fruit or plant growing maybe will be grown.
Can handle all plants and plant parts according to the present invention.Described plant is meant all plants and plant population, for example need with unwanted wild plant, cultivated species (comprising naturally occurring cultivated species) and botanical variety (no matter whether being subjected to the protection of plant variety or plant seedling power).Cultivated species and botanical variety can be the plants that comprises genetically modified plants that the routine breeding assisting or augment by one or more biotechnology methods and method of breeding obtain, described biotechnology rule uses double haploid, protoplast fusion, random mutagenesis and directed mutagenesis, molecular labeling or genetic marker as passing through, perhaps by biotechnology and genetic engineering method.
Described plant parts is meant all ground and underground position and organs of plant, for example bud, leaf, flower (flower), flower (blossom) and root, listed in view of the above for example leaf, needle, stem, branch, flower, fruit body, fruit and seed and root, bulb and rhizome.Crop and asexual and sexual propagation thing are for example transplanted, bulb, rhizome, sarment and seed, also belong to plant parts.
Word among the present invention " plant propagation thing " expression can be used for all vegetable materials of the asexual or sexual propagation of plant.The example of plant propagation thing is transplanted, bulb, rhizome, sarment, seed, fruit, grain, beanpod, fruit body, stem tuber and seedling.
Bond/the composition of the present invention that is used to resist phytopathogenic fungi and/or microorganism and/or insect in crop protection contains effectively but the reactive compound of the present invention of the phytotoxic amount of tool not.The one side that " effectively but not the phytotoxic amount of tool " is defined as bond of the present invention is enough to prevent and treat satisfactorily or eliminate fully the fungal disease of plant, can not causes the amount of any significant phytotoxicity symptom on the other hand.Described effective dose can change in a big way at one usually.This dosage depends on Several Factors, for example the reactive compound of the fungi of being resisted, plant, weather conditions and bond of the present invention.
In can plant by the inventive method protection, the main field crop that can address is corn for example, soybean, cotton, rape oilseeds (Brassica oilseeds) are cabbage type rape (Brassica napus) (for example Canadian rape (canola)) for example, turnip (Brassicarapa), leaf mustard (B.juncea) (for example leaf mustard (mustard)) and brassicacarinata (Brassica carinata), rice, wheat, beet, sugarcane, oat, rye, barley, grain, triticale, flax, liane and various fruit, with various plant classification groups' vegetables for example the rose family (for example belong to kind of (Rosaceae sp.), a kind of fruit, such as apple, pear, etc. is apple and pears for example, reach for example apricot of drupe, cherry, almond and peach, soft fruits is strawberry for example), Ribesioidae sp., Juglandaceae belongs to kind of (a Juglandaceae sp.), Betulaceae belongs to kind of (a Betulaceae sp.), Anacardiaceae belongs to kind of (an Anacardiaceae sp.), Fagaceae belongs to kind of (a Fagaceae sp.), Moraceae belongs to kind of (a Moraceae sp.), Oleaceae belongs to kind of (an Oleaceae sp.), Actinidiaceae belongs to kind of (an Actinidaceae sp.), Lauraceae belongs to kind of (a Lauraceae sp.), Musaceae belongs to kind of (a Musaceae sp.) (for example banana tree and greening tree (plantings)), Rubiaceae belongs to kind of (Rubiaceae sp.) (a for example coffee), Theaceae belongs to kind of (Theaceaesp.), Sterculiaceae belongs to kind of (a Sterculiceae sp.), Rutaceae belongs to kind of (a Rutaceae sp.) (lemon for example, orange and grapefruit); Solanaceae belongs to kind of (a Solanaceae sp.) (tomato for example, potato, capsicum, eggplant), Liliaceae belongs to kind of (a Liliaceae sp.), composite family belongs to kind of (a Compositiae sp.) (lettuce (lettuce) for example, artichoke (artichoke) and witloof (chicoty)---comprise root witloof (root chicory), corn sow thistle (endive) or common witloof (common chicory)), Umbelliferae belongs to kind of (a Umbelliferae sp.) (carrot for example, parsley (parsley), celery (celery) and celeriac), Curcurbitaceae belong to kind of (a Cucurbitaceae sp.) (cucumber for example---comprise pickled with cucumber (pickling cucumber), pumpkin (Squash), watermelon, cucurbit class (gourds) and muskmelon class (melons)), green onion section belongs to kind of (Alliaceae sp.) (for example an onion class and a leek), Cruciferae belongs to kind of (a Cruciferae sp.) (white cabbage (whitecabbage) for example, red cabbage (red cabbage), cabbage (broccoli), cauliflower (cauliflower), brussels sprouts (brussel sprouts), a variety of Chinese cabbage (pak choi), kohlrabi (kohlrabi), radish (radish) and Canadian rape, rape seed (rapeseed), leaf mustard, horseradish (horseradish), Chinese celery (cress), Chinese cabbage (Chinese cabbage), colea (colza)), pulse family belongs to kind of (Leguminosaesp.) (peanut for example, pea class and Kidney bean class, the Kidney bean class---as climning bean (climbingbeans) and broad bean (broad beans)), Chenopodiaceae belongs to kind of (a Chenopodiaceae sp.) (fodder beet (mangold) for example, leaf beet (spinach beet), spinach (spinach), table beet), composite family belongs to kind of (Asteraceae sp.) (a for example sunflower), Papilionaceae belongs to kind of (Papilionaceae sp.) (a for example soybean), Malvaceae (Malvaceae) (for example okra (okra)), Asparagaceae (Asparagaceae) (for example asparagus (asparagus)); Gardening and forest crop; Ornamental plants; And the homologue of the genetic modification of described crop.
Processing method of the present invention is used to handle genetic modified organism (GMOs), for example plant or seed.Genetically modified plant (or genetically modified plants) is that heterologous gene is stably held into genomic plant.The gene that provides or assemble in the plant outside mainly is provided described word " heterologous gene ", and in the time of in this gene is introduced nuclear, chloroplast or mitochondrial genomes by express protein of interest matter or polypeptide or by downward modulation or silence one or more be present in endophytic other gene (for example use antisense technology, suppress technology or RNA interference-RNAi technology altogether) thus give the transformed gene plant new or improved agronomy or other characteristic.The heterologous gene that is positioned at genome is also referred to as transgenosis.The transgenosis that defines according to its particular location in Plant Genome is called as transformation plant or transgenic line (transformation ortransgenic event).
According to plant variety or plant cultivars, its location and growth conditions (soil, weather, vegetation period, nutrition), processing of the present invention also can produce superadditivity (" working in coordination with ") effect.Can obtain the following effect that surpasses actual desired thus: for example can reduce the rate of application of used reactive compound of the present invention and composition and/or widen its activity profile and/or improve its activity, improve plant growing, improve high temperature or cold tolerance, raising is to arid or to the tolerance of salt content in the water or in the soil, improve the quality of blooming, make gather simpler and easy, hasting of maturity, improve the output of gathering, fruit is bigger, plant height is higher, the leaf look greener, bloom more early, improve the quality of the product of gathering and/or improve its nutritive value, improve the sugared concentration in the fruit, improve the bin stability and/or the processing characteristics of the product of gathering.
Preferably plant and the plant cultivars of handling according to the present invention comprises all plants with the gene thing that can give these plants (no matter whether obtaining by breeding and/or biotechnology method) advantageous particularly, useful properties.
Preferably plant and the plant cultivars of handling according to the present invention also has resistance to one or more biological coercing, be the defense that described plant show illustrates improvement, for example to the defense of nematode, insect, mite, phytopathogenic fungi, bacterium, virus and/or viroids to animal and microorganism nuisance.
Plant of handling according to the present invention and plant cultivars also can be coerces those plants with resistance to one or more inanimates.The inanimate stress conditions can comprise mineral contact, ozone contact, the high light contact of the soil salinity, the raising of for example arid, low temperature contact, thermo-contact, osmotic stress, waterflooding, raising, the availability of restricted nitrogen nutrient, restricted phosphorus nutrient availability, avoid shading.
Plant and the plant cultivars handled according to the present invention also can be those plants that are characterized as the productive rate characteristic with raising.The productive rate that described plant is improved can be by for example improved plant physiology, growth and growth---as water-use efficiency, specific retention, and the germination rate of the use of improved nitrogen, the carbon assimilation of raising, improved photosynthesis, raising and hasting of maturity and produce.Productive rate also can be subjected to improved plant architecture (plant arachitecture) (coerce and non-stress conditions under) influence, described plant architecture includes but not limited to early flowering, the seed number of generation, seed vitality, plant size, stipes number (internode number) and distance, root growth, seed size, fruit size, pod size, pod number or spike number, each pod or the fringe of the control hybrid seed of blooming, seed quality, the seed plumpness of raising, the seed dispersal of reduction, the pod of reduction ftracture and lodging resistance.Yield characteristics also comprises seed compositions---for example carbohydrate content, protein content, oil content and composition, the reduction of nutritive value, anti-nutrient compounds, improved processing characteristics and stability for storage.
The plant of handling according to the present invention can be the hybrid plant of the characteristic that shows hybrid vigour or hybrid vigor, and this hybrid vigor can cause higher productive rate, vigor, health degree and usually to the resistance of biology and abiotic stress factor.Described plant is usually by a kind of selfing male sterile parent line (female parent) is made with another kind of selfing male fertility parent line (male parent) hybridization.Hybrid seed is gathered from male sterile plants usually and is sold to the grower.Male sterile plants (for example corn) sometimes makes by castration, and promptly machinery is removed male reproductive organ (or male flower), and still, more generally, male sterile is to be produced by the hereditary factor in the Plant Genome.In the case, especially when wishing that the product of gathering from hybrid plant is kind of a period of the day from 11 p.m. to 1 a.m, that guarantees the hybrid plant male fertile recovers normally useful fully.This can have the suitable [fertility that can recover the hybrid plant male fertility to realize by guaranteeing male parent, and described hybrid plant contains is responsible for male sterile hereditary factor.The male sterile hereditary factor can be arranged in cytoplasm.The example of cytoplasmic male sterility (CMS) for example is described in Brassicas (Brassica species).But the male sterile hereditary factor also can be arranged in the nuclear gene group.Male sterile plants also can obtain by Plant Biotechnology rule such as gene engineering.The useful especially method that obtains male sterile plants is recorded in WO 89/10396, wherein ribalgilase (for example barnase) selective expression in the tapetal cell of stamen for example.Then fertilizability can by ribonuclease inhibitor for example the expression of barstar in tapetal cell recover.
The plant that can handle according to the present invention or plant cultivars (obtaining by Plant Biotechnology rule such as gene engineering) are the plant of herbicide tolerant, promptly make the plant that one or more given weed killer herbicides are had tolerance.Described plant also can obtain by genetic transformation or by selecting to contain the plant that gives described herbicide tolerant sudden change.
The herbicide tolerant plant has for example glyphosate (glyphosate) tolerant plants, promptly makes the plant that glyphosate or its esters weed killer herbicide are had tolerance.Can prepare the plant that glyphosate is had tolerance by diverse ways.For example the glyphosate tolerant plant can be by obtaining with coding 5-enol pyruvoyl shikimic acid-3-phosphate synthase (5-enolpyruvylshikimate-3-phosphate synthase) gene-transformed plant (EPSPS).The example of described EPSPS gene have AroA gene (mutant CT7), Agrobacterium (Agrobacterium) bacterium of salmonella typhimurium (Salmonella typhimurium) bacterium the CP4 gene, be encoded to the gene of petunia EPSPS, tomato EPSPS or Eleusine EPSPS.The EPSPS gene also can be the EPSPS of sudden change.The glyphosate tolerant plant also can obtain by the gene of expressing the coding glyphosate oxidoreductase.The glyphosate tolerant plant also can obtain by the gene of expressing the coding glyphosate acetyl transferase.The glyphosate tolerant plant also can obtain by selecting to contain the natural plant that exists said gene to suddenly change.
Other herbicide tolerant plant has the plant that for example weed killer herbicide that suppresses glutamine synthelase is had tolerance, and described weed killer herbicide is bialaphos (bialaphos), careless fourth phosphine (phosphinothricin) or careless ammonium phosphine (glufosinate) for example.Described plant can have the glutamine synthelase mutant of tolerance to obtain by the enzyme of expression detoxifcation weed killer herbicide or to inhibitory action.An effective described enzyme (for example the bar albumen or the pat albumen of streptomycete (Streptomyces) genus) of separating toxenzyme for the careless fourth phosphinothricin acetyl transferase of coding.The plant of expressing external source grass fourth phosphinothricin acetyl transferase also is described.
Other herbicide tolerant plant also can be the plant that the weed killer herbicide that suppresses the two oxidase (HPPD) of medical midbodies of para (ortho)-hydroxybenzoic acetone acid is had tolerance.The two oxidase of medical midbodies of para (ortho)-hydroxybenzoic acetone acid are enzymes that catalysis changes into p-hydroxybenzene pyruvic acid (HPP) reaction of alcapton.Transform to the gene of the naturally occurring anti-HPPD enzyme of plant available code of HPPD inhibitor tolerance or with the gene of the HPPD enzyme of encoding mutant.Also can be to the tolerance of HPPD inhibitor by some transforms and obtain no matter the HPPD inhibitor can form the gene pairs plant of the enzyme of alcapton to the inhibitory action of natural HPPD enzyme with coding.Plant, also can be improved by the gene-transformed plant with the prephenate dehydrogenase (prephenate dehydrogenase) of encoding except that the gene with coding HPPD tolerance enzyme the tolerance of HPPD inhibitor.
Other herbicide tolerant plant is the plant for acetolactate synthase (ALS) inhibitor is had tolerance also.Known ALS inhibitor comprises, for example sulfonylureas, imidazolone, triazolo pyrimidine class (triazolopyrimidines), pyrimidine oxygen (sulphur) benzoates (pyrimidinyoxy (thio) benzoates) and/or Herbicidal sulphonylamino carbonyl triazole quinoline ketone (sulfonylaminocarbonyltriazolinone) weed killer herbicide.The difference sudden change of known ALS enzyme (being also referred to as acetohydroxy acid synthetase, AHAS) makes it have tolerance to different weed killer herbicides and weed killer herbicide group.Production to sulfonylureas tolerant plants and imidazolinone-tolerant plant is described.Other imidazolinone-tolerant plant also is described.Other sulfonylureas tolerant plants and imidazolinone-tolerant plant also for example are being described among the WO 2007/024782.
Other the plant that imidazolone and/or sulfonylureas are had a tolerance can obtain by mutagenesis, the selection under the situation that weed killer herbicide exists in the cell culture or the described mutation breeding that for example soybean, rice, beet, lettuce or sunflower are carried out.
Also the plant that can handle according to the present invention or plant cultivars (obtaining by Plant Biotechnology rule such as gene engineering) are the genetically modified plants with insect tolerance, the plant that promptly invasion and attack of some targeted insect is had resistance.Described plant can obtain by genetic transformation or by the plant of selecting to contain the sudden change that can give described insect-resistant.
" genetically modified plants with insect-resistant " used herein comprise and contain at least a genetically modified any plant, and described transgenosis contains the coded sequence of the following albumen of encoding:
1) insecticidal crystal protein of bacillus thuringiensis,Bt (Bacillus thuringiensis) or its desinsection part, people such as Crickmore for example, Microbiology and MolecularBiology Reviews (1998), 62,807-813 is listed, people such as Crickmore (2005) to the thuringiensis bacillus toxin nomenclature upgraded (online: insecticidal crystal protein http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/), perhaps its desinsection part, for example protein-based Cry1Ab of Cry, Cry1Ac, Cry1F, Cry2Ab, the protein of Cry3Aa or Cry3Bb or its desinsection part; Perhaps
2) crystalline protein of bacillus thuringiensis,Bt or its part, this part is in another other crystalline protein or its part of bacillus thuringiensis,Bt---for example the binary toxin of being made up of Cry34 and Cry35 crystalline protein---has insecticidal activity under the situation of existence; Perhaps
3) contain the hybrid insecticidal proteins of the different insecticidal crystal proteins part of bacillus thuringiensis,Bt, as above-mentioned 1) hybrid albumen or above-mentioned 2) hybrid albumen, the Cry1A.105 albumen that makes by the corn of MON98034 strain system for example; Perhaps
4) any one albumen above-mentioned 1)-3), some of them, a particularly 1-10 amino acid obtained by another aminoacid replacement to higher insecticidal activity of targeted insect kind and/or expansion influence the scope of targeted insect kind and/or owing in clone or conversion process, introduce the change of coding DNA, for example Cry3Bb1 albumen in MON863 or the MON88017 corn or the Cry3A albumen in the MIR604 corn;
5) the desinsection secretory protein of bacillus thuringiensis,Bt or Bacillus cercus (Bacillus cereus) or its desinsection part, for example list in the Vegetative Insecticidal Proteins (VIP) of following network address: http://www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt/vip.html, for example albumen of VIP3Aa protide; Perhaps
6) secretory protein of bacillus thuringiensis,Bt or Bacillus cercus, this albumen is at another secretory protein of bacillus thuringiensis,Bt or Bacillus cercus---for example the binary toxin of being made up of VIP1A and VIP2A albumen---has insecticidal activity under the situation of existence; Perhaps
7) contain the hybrid insecticidal proteins of the different secretory proteins part of bacillus thuringiensis,Bt or Bacillus cercus, for example above-mentioned 1) hybrid albumen or above-mentioned 2) hybrid albumen; Perhaps
8) any one albumen above-mentioned 1)-3), some of them, a particularly 1-10 amino acid is obtained the scope of higher insecticidal activity of targeted insect kind and/or targeted insect kind that expansion influences and/or owing to introduces the change (therebetween still encoding insecticidal proteins) of coding DNA, for example the VIP3Aa albumen in the COT102 corn in clone or conversion process by another aminoacid replacement.
Certainly, insect tolerance genetically modified plants used herein also comprise any plant of the combination of the gene that contains coding above-mentioned 1-8 class any one albumen.In one embodiment, the insect tolerant plants comprises the transgenosis more than any one albumen of the above-mentioned 1-8 class of a kind of coding, thus when the different albumen that uses at the different target caste scope of targeted insect kind that expansion influences; Thereby the perhaps generation of insect-resistant in the delay plant by using different albumen, described albumen has insecticidal activity to the same target caste but has the different modes of action, for example is bonded to the different receptor binding sites of insect.
Also the plant that can handle according to the present invention or plant cultivars (obtaining by Plant Biotechnology rule such as gene engineering) have tolerance to abiotic stress.Described plant can obtain by genetic transformation or by the plant of selecting to contain the sudden change that can give described stress resistance.Useful especially stress tolerant plants comprises:
A. contain and to reduce the genetically modified plant that polyadenous glycosides diphosphonic acid-ribose in plant cell or the plant aggregates into enzyme (PARP) expression of gene and/or its activity.
B. contain the expression of the PARG encoding gene that can reduce plant or plant cell that increases stress tolerance and/or the genetically modified plant of its activity.
C. contain the genetically modified plant that the plant function enzyme to the salvage route of NADH that improves stress tolerance is encoded, described plant function enzyme comprises nicotinamidase, nicotinate phosphoribosyl transferase, NAMN adenine transferase, NADH synzyme or nicotinamide phosphoribosyl transferase.
Have the above-mentioned plant of mentioning feature the non-limit of example list in the Table A.
Table A
| Sequence number | Action target or one or more principles that showed | Crop phenotype/following material is produced tolerance |
| A-1 | Acetolactate synthase (ALS) | Sulfonylureas, imidazolone, triazolo pyrimidine class, pyrimidine radicals oxybenzoic acid ester class, phthalide-type (Phtalides) |
| A-2 | Acetyl-CoA carboxylase (ACCase) | Aryloxy group phenoxy group alkanecarboxylic acid class, cyclohexyl diketone |
| A-3 | The two oxidase (HPPD) of medical midbodies of para (ortho)-hydroxybenzoic acetone acid | Isoxazole is isoxaflutole (isoxaflutol) or isoxachlorotole (isoxachlortol) for example, and three ketones is mesotrione (mesotrione) or sulphur humulone (sulcotrione) for example |
| A-4 | Grass fourth phosphinothricin acetyl transferase | Grass fourth phosphine |
| A-5 | The O-methyltransferase | Levels of lignin is changed |
| A-6 | Glutamine synthelase | Grass ammonium phosphine, bialaphos |
| A-7 | Adenylosuccinic acid splits synzyme (ADSL) | The inhibitor that IMP and AMP are synthetic |
| Sequence number | Action target or one or more principles that showed | Crop phenotype/following material is produced tolerance |
| A-8 | Adenylosuccinate synthetase | The adenylosuccinic acid synthetic inhibitor |
| A-9 | Anthranilate synthase | Synthetic and the catabolic inhibitor of tryptophan |
| A-10 | Nitrilase | 3,5-dihalo--4-hydroxyl-phenylcyanide class is Brominal (bromoxynil) and ioxynil (ioxinyl) for example |
| A-11 | 5-enol pyruvoyl-3-phosphoric acid shikimic acid (5-enolpyruvyl-3-phosphoshikimate) synzyme (EPSPS) | Glyphosate or sulphosate (sulfosate) |
| A-12 | Glyphosate oxidoreductase | Glyphosate or sulphosate |
| A-13 | Proporphyrinogen oxidase (PROTOX) | Diphenyl ether, cyclic imide class, phenyl pyrazoles, pyridine derivate, phenopylate, oxadiazole class etc. |
| A-14 | Cytochrome P450 is P450 SU1 for example | Xenobiotic and weed killer herbicide be sulfonylurea for example |
| A-15 | Dimboa biosynthesis (Bx1 gene) | Exserohilum turcicum (Helminthosporium turcicum), corn leaf aphids (Rhopalosiphum maydis), corn stalk rot disease (Diplodia maydia), corn borer (Ostrinia nubilalis), Lepidoptera belong to |
| A-16 | CM III (little basic corn seed peptide (small basic maize peptide)) | Phytopathogen is sickle spore bacterium (fusarium), alternaric bacteria (alternaria), sclerotinite (sclerotina) for example |
| Sequence number | Action target or one or more principles that showed | Crop phenotype/following material is produced tolerance |
| A-17 | Corn-SAFP (zeamatin) | Phytopathogen is sickle spore bacterium, alternaric bacteria, sclerotinite, rhizoctonia (rhizoctonia), cupreum (chaetomium), palpus mould (phycomyces) for example |
| A-18 | The Hm1 gene | Cochliobolus (Cochliobulus) |
| A-19 | The chitin enzyme | Phytopathogen |
| A-20 | The glucan enzyme | Phytopathogen |
| A-21 | The coat protein class | Virus, for example maize dwarf mosaic virus, corn chlorisis stunt virus |
| A-22 | Thuringiensis bacillus toxin class, VIP3, Bacillus cercus endotoxin, luminous bacillus (Photorabdus) and Xenorhabdus toxin (Xenorhabdus toxins) | Lepidoptera, coleoptera (coleoptera), diptera (diptera), nematoda, for example corn borer, Heliothis zea (heliothis zea), armyworm class, for example greedy noctuid (Spodoptera frugiperda) in meadow, pumpkin 12 asterophyllite first (corn rootworms), sesamia genus, black cutworm (black cutworm), Asiatic corn borer (asian corn borer), trunk insects (weevils) |
| A-23 | 3-hydroxy steroid oxidase | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| Sequence number | Action target or one or more principles that showed | Crop phenotype/following material is produced tolerance |
| A-24 | Peroxidase | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| A-25 | Amastatin class, for example leucine amino peptidase inhibitor (LAPI) | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| A-26 | The limonene synzyme | Pumpkin 12 asterophyllite Class As |
| A-27 | The agglutinin class | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| A-28 | Protease inhibitors class, for example cystatin, patatin, virgiferin, CPTI | Trunk insects, pumpkin 12 asterophyllite Class As |
| A-29 | Ribosome inactivating protein | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| Sequence number | Action target or one or more principles that showed | Crop phenotype/following material is produced tolerance |
| A-30 | Corn 5C9 polypeptide | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| A-31 | The HMG-CoA reductase | Lepidoptera, coleoptera, diptera, nematoda, for example corn borer, Heliothis zea, the armyworm class is the greedy noctuid in meadow, pumpkin 12 asterophyllite first, sesamia genus, black cutworm, Asiatic corn borer, trunk insects for example |
| A-32 | The inhibitory action of protein synthesis | Chloracetophenone amine, for example alachlor (alachlor), Acetochlor (acetochlor), dimethenamid (dimethenamid) |
| A-33 | The hormone analogies | 2,4-D, mecopropP (mecoprop-P) |
Also the plant that can handle according to the present invention or plant cultivars (obtaining by Plant Biotechnology rule such as gene engineering) show the change of quantity, quality and/or the bin stability of the product of gathering, and/or the change of the concrete composition characteristic of the product of gathering, for example:
1) genetically modified plants of synthesis modification starch, this modified starch its physico chemical property, especially amylose content or amylose/amylopectin ratios, branch degree, average chain length, side chain distribution, viscosity, gel strength, starch granularity and/or starch grain form, compare with the synthetic starch of wild-type plant cell or plant change has taken place, thereby can be suitable for better specifically using like this
2) synthetic non-starch carbohydrate polymer or syntheticly compare the non-starch carbohydrate polymer of character and do not carry out the genetically modified plants of genetic modification with change with wild-type plant.The plant that example has generation polyfructosan (polyfructose)---especially inulin and levulan type---produces α-1, and the plant of 4-glucan produces α-1,6 branched alpha-1, and the plant of 4-glucan produces the plant of alternan,
3) genetically modified plants of generation hyaluronan.
The useful especially genetically modified plants that can handle according to the present invention are the combination that contains transformation plant or transformation plant, be the plant of the application theme of non-control state (non-regulated status), whether this application proposes to United States Department of Agriculture (USDA) animals and plants sanitary inspection administration (APHIS) in the U.S., no matter apply for authorizing or still undecided.Whenever all can locate easily to obtain this information from APHIS (4700 River Road Riverdale, MD 20737, the U.S.)---for example on its website (URL http://www.aphis.usda.gov/brs/not_reg.html)---.The APHIS application submission date pendent or the non-control state application that APHIS authorizes is the listed submission date among the table B, contains following information among the table B:
Application: the identification number of application (identification number).Find technical description the independent application documents that---for example from the APHIS website---number obtain by this application from APHIS to transformation plant.These descriptions are included this paper in way of reference.
The prolongation (extension of petition) of application: quote prolong request at original application.
Mechanism: the title of submitting the entity of this application to.
The material of institute's control (regulated article): corresponding plants kind.
Transgenosis phenotype: the feature of giving plant by transformation plant.
Transformation plant or conversion system: the individual plant system of the non-control state that requires or the title of many strains system (also being named as monosystem or polyphyly (line or lines) sometimes).
Various files of relevant this application that APHIS file: APHIS announces and the various files that can require to APHIS.
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| B-1 | 07-253-01p | Just reach earlier | Corn | The MIR-162 corn | |||||
| B-2 | 07-180-01p | Good fortune Raleigh gene (Florigene) company | Carnation | Pattern changes | IFD-1989Φ- 1& IFD-199Φ7- 9 | ||||
| B-3 | 07-152-01p | The pioneer | Corn | Glyphosate ﹠ imidazolinone-tolerant | HT-98140 | ||||
| B-4 | 07-108-01p | Just reach earlier | Cotton | The Lepidoptera resistance | COT67B | ||||
| B-5 | 06-354-01p | The pioneer | Soybean | High oleic acid | DP-3Φ5423- 1 | ||||
| B-6 | 06-332-01p | The Baeyer crop science | Cotton | Glyphosate tolerant | GHB614 | ||||
| B-7 | 06-298-01p | Meng Shan | Corn | The European corn borer resistance | MON?89034 | ||||
| B-8 | 06-271-01p | The pioneer | Soybean | Glyphosate ﹠ acetolactate synthase tolerance | 356043 | On October 5th, 2007 | 06-271-01p_ pea | ||
| B-9 | 05-280-01p | Just reach earlier | Corn | The warm tolerance α-Dian Fenmei | 3272 | ||||
| B-10 | 04-337-01p | The University of Florida | Papaya papaw | The PRSV resistance | X17-2 |
| B-11 | 04-110-01p | Meng Shan is Forage Genetics | Clover | Glyphosate tolerant | J101、J163 | On March 23rd, 2007; On June 27th, 2005; On February 3rd, 2005; On November 24th, 2004 | 04-110-01p_ pea | 04-110-01p_ com | |
| B-12 | 03-104-01p | Meng Shan | Creeping bentgrass | Glyphosate tolerant | ASR368 | Area under one's jurisdiction and shape | 03-104-01p_ |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| Scotts | Attitude; On October 12nd, 2005; On April 11st, 2005; On November 18th, 2004; On September 24th, 2004; On January 5th, 2004 | Ra﹠CBG white paper (White Paper) | |||||||
| B-13 | 06-234-01p | 98-329-01p | The Baeyer crop science | Rice | Grass fourth phosphine tolerance | LLRICE601 | On December 4th, 2006; On September 8th, 2006; | 06-234-01p_ pea | 06-234-01p_ com |
| B-14 | 06-178-01p | Meng Shan | Soybean | Glyphosate tolerant | MON?89788 | On August 2nd, 2007; On February 5th, 2007; | 06-178-01p_ pea | 06-178-01p_ com | |
| B-15 | 04-362-01p | Just reach earlier | Corn | Be protected from the infringement of pumpkin 12 asterophyllite first | MIR604 | On March 23rd, 2007; On February 22nd, 2007; On January 10th, 2007; | 04-362-01p_ pea | 04-362-01p_ com | |
| B-16 | 04-264-01p | Agricultural Research Administration of U.S. farming portion (ARS) | Plum | The plumpox virus resistance | C5 | On July 13rd, 2007; On May 16th, 2006; | 04-264-01p_ pea | 04-264-01p_ com | |
| B-17 | 04-229-01p | Meng Shan | Corn | High-lysine | LY038 | On February 3rd, 2006; On September 27th, 2005; | 04-229-01p_ pea | 04-229-01p_ com | |
| B-18 | 04-125-01p | Meng Shan | Corn | Pumpkin 12 asterophyllite first resistances | 88017 | On January 6th, 2006; | 04-125-01p_ pea | 04-125-01p_ com |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| On August 12nd, 2005; | |||||||||
| B-19 | 04-086-01p | Meng Shan | Cotton | Glyphosate tolerant | MON?88913 | On January 3rd, 2005; On November 24th, 2004; On October 4th, 2004; | 04-086-01p_ pea | 04-086-01p_ com | |
| B-20 | 03-353-01p | The road | Corn | Pumpkin 12 asterophyllite first resistances | 59122 | On August 7th, 2005; On July 1st, 2005; | 03-353-01p_ pea | 03-353-01p_ com | |
| B-21 | 03-323-01p | Meng Shan | Sugar beet | Glyphosate tolerant | H7-1 | On March 17th, 2005; On October 19th, 2004; | 03-323-01p_ pea | 03-323-01p_ com | |
| B-22 | 03-181-01p | 00-136-01p | The road | Corn | Lepidoptera resistance ﹠ grass fourth phosphine tolerance | TC-6275 | On November 1st, 2004; On August 17th, 2004; | 03-181-01p_ pea | 03-181-01p_ com |
| B-23 | 03-155-01p | Just reach earlier | Cotton | The Lepidoptera resistance | COT102 | On July 20th, 2005; On January 28th, 2005; | 03-155-01p_ pea | 03-155-01p_ com | |
| B-24 | 03-036-01p | The Mycogen/ road | Cotton | The Lepidoptera resistance | 281-24-236 | On August 13rd, 2004; On March 9th, 2004; | 03-036-01p_ pea | 03-036-01p_ com | |
| B-25 | 03-036-02p | The Mycogen/ road | Cotton | The Lepidoptera resistance | 3006-210-23 | On August 13rd, 2004; March 9 in 2004 | 03-036-02p_ pea | 03-036-02p_ com |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| Day; | |||||||||
| B-26 | 02-042-01p | An Wante | Cotton | Grass fourth phosphine tolerance | LLCotton25 | 02-042-01p_ com | |||
| B-27 | 01-324-01p | 98-216-01p | Meng Shan | Rape seed | Glyphosate tolerant | RT200 | 01-324-01p_ com | ||
| B-28 | 01-206-01p | 98-278-01p | An Wante | Rape seed | Grass fourth phosphine tolerance ﹠ pollination control (pollinati on control) | MS1&RF1/RF2 | 01-206-01p_ com | ||
| B-29 | 01-206-02p | 97-205-01p | An Wante | Rape seed | Grass fourth phosphine tolerance | Topas?19/2 | 01-206-02p_ com | ||
| B-30 | 01-137-01p | Meng Shan | Corn | Pumpkin 12 asterophyllite first resistances | MON?863 | 01-137-01p_ com | |||
| B-31 | 01-121-01p | Dimension cut (Vector) | Tobacco | Nicotine reduces | Vector?21-41 | 01-121-01p_ com | |||
| B-32 | 00-342-01p | Meng Shan | Cotton | The Lepidoptera resistance | Cotton?Event 15985 | 00-342-01p_ com | |||
| B-33 | 00-136-01p | Mycogenc/o road ﹠ pioneer | Corn | Lepidoptera resistance ﹠ grass fourth phosphine tolerance | Line?1507 | 00-136-01p_ com | |||
| B-34 | 00-011-01p | 97-099-01p | Meng Shan | Corn | Glyphosate tolerant | NK603 | 00-011-01p_ com | ||
| B-35 | 99-173-01p | 97-204-01p | Meng Shan | Potato | The PLRV﹠CPB resistance | RBMT22-82 | 99-173-01p_ com | ||
| B-36 | 98-349-01p | 95-228-01p | Ai Gefu | Corn | Grass fourth phosphine tolerance and male sterile | MS6 | 98-349-01p_ com | ||
| B-37 | 98-335-01p | Sa Sika river university | Flax | Tolerance to the sulfonylurea herbicide pedo relict | CDC?triffid | 98-335-01p_ com | |||
| B-38 | 98-329-01p | Ai Gefu | Rice | Grass fourth phosphine tolerance | LLRICE06、 LLRICE62 | 98-329-01p_ com |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| B-39 | 98-278-01p | Ai Gefu | Rape seed | Grass fourth phosphine tolerance ﹠ pollination control | MS8&RF3 | 98-278-01p_ com | |||
| B-40 | 98-238-01p | Ai Gefu | Soybean | Grass fourth phosphine tolerance | GU262 | 98-238-01p_ com | |||
| B-41 | 98-216-01p | Meng Shan | Rape seed | Glyphosate tolerant | RT73 | 98-216-01p_ com | |||
| B-42 | 98-173-01p | The seed Meng Shan of Novartis | Beet | Glyphosate tolerant | GTSB77 | 98-173-01p_ com | |||
| B-43 | 98-014-01p | 96-068-01p | Ai Gefu | Soybean | Grass fourth phosphine tolerance | A5547-127 | 98-014-01p_ com | ||
| B-44 | 98-342-01p | The pioneer | Corn | Male sterile ﹠ grass fourth phosphine tolerance | 676、678、680 | 97-342-01p_ com | |||
| B-45 | 98-339-01p | Meng Shan | Potato | The CPB﹠PVY resistance | RBMT15-101、 SEMT15-02、 SEMT15-15 | 97-339-01p_ com | |||
| B-46 | 97-336-01p | Ai Gefu | Beet | Grass fourth phosphine tolerance | T-120-7 | 97-336-01p_ com | |||
| B-47 | 97-287-01p | Meng Shan | Tomato | The Lepidoptera resistance | 5345 | 97-287-01p_ com | |||
| B-48 | 97-265-01p | Ai Gefu | Corn | Grass fourth phosphine tolerance ﹠ Lepidoptera resistance | CBH-351 | 97-265-01p_ com | |||
| B-49 | 97-205-01p | Ai Gefu | Rape seed | Grass fourth phosphine tolerance | T45 | 97-205-01p_ com | |||
| B-50 | 97-204-01p | Meng Shan | Potato | The CPB﹠PLRV resistance | RBMT21-129& RBMT21-350 | 97-204-01p_ com | |||
| B-51 | 97-148-01p | (Bejo) for a long time | Witloof (Cichorium intybus) | Male sterile | RM3-3、 RM3-4、RM3-6 | 97-148-01p_ com | |||
| B-52 | 97-099-01p | Meng Shan | Corn | Glyphosate tolerant | GA21 | 97-099-01p_ com |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| B-53 | 97-013-01p | Ka Erjing (Calgene) | Cotton | Brominal tolerance ﹠ Lepidoptera resistance | Events 31807&31808 | 97-013-01p_ com | |||
| B-54 | 97-008-01p | Du Pont | Soybean | Oil component (Oil profile) changes | G94-1、 G94-19、 G-168 | 97-008-01p_ com | |||
| B-55 | 96-317-01p | Meng Shan | Corn | Cao Ganlinnaishouxing ﹠ECB resistance | MPN802 | 96-317-01p_ com | |||
| B-56 | 96-291-01p | Enlightening card (Dekalb) | Corn | The European corn borer resistance | DBT418 | 96-291-01p_ com | |||
| B-57 | 96-248-01p | 92-196-01p | Ka Erjing | Tomato | The fruit maturation cyclomorphosis | Increase by 1 FLAVRSAVR system | 96-248-01p_ com | ||
| B-58 | 96-068-01p | Ai Gefu | Soybean | Grass fourth phosphine tolerance | W62、W98、 A2704-12、 A2704-21、 A5547-35 | 96-068-01p_ com | |||
| B-59 | 96-051-01p | Cornell University | Papaya papaw | The PRSV resistance | 55-1、63-1 | 96-051-01p_ com | |||
| B-60 | 96-017-01p | 95-093-01p | Meng Shan | Corn | The European corn borer resistance | MON809& MON810 | 96-017-01p_ com | ||
| B-61 | 95-352-01p _com | Refined scholar brother (Asgrow) | Pumpkin | CMV, ZYMV, WMV2 resistance | CZW-3 | 95-352-01p_ com | |||
| B-62 | 95-338-01p | Meng Shan | Potato | The CPB resistance | SBT02-5& SBT02-7、 ATBT04-6& ATBT04-27、 ATBT04-30、 ATBT04-31、 ATBT04-36 | 95-338-01p_ com | |||
| B-63 | 95-324-01p | Agritope | Tomato | The fruit maturation cyclomorphosis | 35?1N | 95-324-01p_ com | |||
| B-64 | 95-256-01p | Du Pont | Cotton | The sulfonylureas tolerance | 19-51a | 95-256-01p_ |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| com | |||||||||
| B-65 | 95-228-01p | Plant Genetic Systems | Corn | Male sterile | MS3 | 95-228-01p_ com | |||
| B-66 | 95-195-01p | Nuo Siluboken (Northrup King) | Corn | The European corn borer resistance | Bt11 | 95-195-01p_ com | |||
| B-67 | 95-179-01p | 92-196-01p | Ka Erjing | Tomato | The fruit maturation cyclomorphosis | Increase by 2 FLAVRSAVR systems | 95-179-01p_ com | ||
| B-68 | 95-145-01p | The enlightening card | Corn | Grass fourth phosphine tolerance | B16 | 95-145-01p_ com | |||
| B-69 | 95-093-01p | Meng Shan | Corn | The Lepidoptera resistance | MON?80100 | 95-093-01p_ com | |||
| B-70 | 95-053-01p | Meng Shan | Tomato | The fruit maturation cyclomorphosis | 8338 | 95-053-01p_ com | |||
| B-71 | 95-045-01p | Meng Shan | Cotton | Glyphosate tolerant | 1445、1698 | 95-045-01p_ com | |||
| B-72 | 95-030-01p | 92-196-01p | Ka Erjing | Tomato | The fruit maturation cyclomorphosis | Increase by 20 FLAVRSAVR systems | 95-030-01p_ com | ||
| B-73 | 94-357-01p | Ai Gefu | Corn | Grass fourth phosphine tolerance | T14、T25 | 94-357-01p_ com | |||
| B-74 | 94-319-01p | Sheba seed (Ciba Seeds) | Corn | The Lepidoptera resistance | Event?176 | 94-319-01p_ com | |||
| B-75 | 94-308-01p | Meng Shan | Cotton | The Lepidoptera resistance | 531、757、 1076 | 94-308-01p_ com | |||
| B-76 | 94-290-01p | Jie Likang U.S. skin holder (Petoseed) | Tomato | Fruit polygalacturonase content reduces | B、Da、F | 94-290-01p_ com | |||
| B-77 | 94-257-01p | Meng Shan | Potato | The coleoptera resistance | BT6、BT10、 | March nineteen ninety-five | 94-257-01p_ | 94-257-01p_ |
| Application | The original applying number * * * that prolongs | Mechanism | The material of institute's control | The transgenosis phenotype | Transformation plant or conversion system | The FR day for announcing | Preliminary inquiry * * * * or risk assessment | Final examination ﹠ decision | |
| BT12、BT16、 BT17、BT18、 BT23 | 10 days | ea | com | ||||||
| B-78 | 94-230-01p | 92-196-01p | Ka Erjing | Tomato | The fruit maturation cyclomorphosis | Increase by 9 FLAVRSAVR systems | 94-230-01p_ com | ||
| B-79 | 94-228-01p | DNA?Plant Tech | Tomato | The fruit maturation cyclomorphosis | 1345-4 | January 24 nineteen ninety-five | 94-228-01p_ ea | 94-228-01p_ com | |
| B-80 | 94-227-01p | 92-196-01p | Ka Erjing | Tomato | The fruit maturation cyclomorphosis | Line?N73 1436-111 | On October 3rd, 1994 | 94-227-01p_ com | |
| B-81 | 94-090-01p | Ka Erjing | Rape seed | Oil component changes | pCGN3828-21 2/86-18&23 | 94-090-01p_ com | |||
| B-82 | 93-258-01p | Meng Shan | Soybean | Glyphosate tolerant | 40-3-2 | 93-258-01p_ com | |||
| B-83 | 93-196-01p | Ka Erjing | Cotton | The Brominal tolerance | BXN | On February 22nd, 1994 | 93-196-01p_ com | ||
| B-84 | 92-204-01p | Upjohn | Pumpkin | The WMV2﹠ZYMV resistance | ZW20 | On December 13rd, 1994 | 92-204-01p_ ea | 92-204-01p_ com | |
| B-85 | 92-196-01p | Ka Erjing | Tomato | The fruit maturation cyclomorphosis | FLAVRSAVR | On October 19th, 1992 | 92-196-01p_ com |
The useful especially genetically modified plants that can handle according to the present invention are for listing in the plant among the table B with its trade (brand) name.
Table B
| Sequence number | Trade (brand) name | Example | Describe |
| B-86 | Roundup?Ready _ | Beet (Beta vulgaris) (sugar beet) | H7-1 strain system |
| B-87 | InVigor _ | Cabbage type rape (Argentinian rape | Rape by genetic modification is: Φ expresses and gives weed killer herbicide grass ammonium phosphine |
| Sequence number | Trade (brand) name | Example | Describe |
| (Argentine Canola)) | The gene of (glufosinate ammonium) tolerance; Φ is on the basis at the male sterile (MS) and the fertility restorer (RF) of genetic modification, introduces the novel hybrid breeding system of rape; Φ expresses the gene to antibiotic resistance. | ||
| B-88 | Liberty Link _ | Cabbage type rape (Argentinian rape) | Has careless fourth phosphine tolerance |
| B-89 | Roundup Ready _ | Cabbage type rape (rape) | MON89249-2 (GT200) strain system |
| B-90 | Clearfield _ | Rape | Non-transgenic (Non-GMO), (imazamox) has tolerance to imazamox |
| B-91 | Optimum TMGAT TM | Soybean (Glycine max L.) | Glyphosate and ALS weed killer herbicide had tolerance |
| B-92 | Roundup Ready _ | Soybean | MON-Φ 4 Φ 32-6 (GTS 40-3-2) |
| B-93 | Roundup RReady2Yield TM | Soybean | MON-89788-1 (MON89788) strain system |
| B-94 | STS _ | Soybean | Has the sulfonylurea tolerance |
| B-95 | YIELD GARD _ | Soybean | |
| B-96 | AFD _ | Upland cotton (Gossypium hirsutum L.) (cotton) | Be to comprise for example AFD5062LL, AFD5064F, AFD5065B2F including for example Bollgard in _, Bollgard II, Roundup Ready, Roundup Ready Flex, and LibertyLink _The AFD seed of several variants of technology is effective. |
| B-97 | Bollgard?II _ | Upland cotton (cotton) | MON 15985 strains system: Cry2 (A) b1; Cry1A (c) |
| B-98 | Bollgard _ | Upland cotton (cotton) | MON531/757/1076 strain system: Cry1Ac |
| Sequence number | Trade (brand) name | Example | Describe |
| B-99 | FiberMax _ | Upland cotton (cotton) | Improved fiber quality |
| B-100 | Liberty?Link _ | Upland cotton (cotton) | Grass fourth phosphine tolerance |
| B-101 | Nucotn?33B | Upland cotton (cotton) | Bt toxin in the Delta Pine system: Cry1Ac |
| B-102 | Nucotn?33B | Upland cotton (cotton) | Bt toxin in the Delta Pine system: Cry1Ac |
| B-103 | Nucotn _ | Upland cotton (cotton) | Bt toxin in the Delta Pine system |
| B-104 | PhytoGen TM | Upland cotton (cotton) | Comprise and contain for example variant of Roundup Ready Flex, Widestrike |
| B-105 | Roundup?Ready?Flex _ | Upland cotton (cotton) | MON88913 strain system |
| B-106 | Roundup?Ready _ | Upland cotton (cotton) | MON1445/1698 strain system |
| B-107 | Widestrike TM | Upland cotton (cotton) | Cry1F and Cry1Ac |
| B-108 | YIELD?GARD _ | Upland cotton (cotton) | |
| B-109 | Roundup?Ready _ | Lucerne (Medicago sativa) (clover) | MON-Φ Φ 1 Φ 1-8, MON-Φ Φ 163-7 (J101, J163) strain system |
| B-110 | Clearfield _ | Rice (Oryza sativa) | Non-transgenic has tolerance to imazamox |
| B-111 | Atlantic?and?Superior NewLeaf | Potato (Solanum tuberosum L.) | ATBT04-6、ATBT04-27、ATBT04-30、ATBT04-31、 ATBT04-36、SPBT02-5、SPBT02-7 |
| B-112 | NewLeaf _ | Potato | For example contain strain system: RBMT15-101, SEMT15-02, SEMT15-15 |
| Sequence number | Trade (brand) name | Example | Describe |
| B-113 | NewLeaf _plus | Potato | For example contain strain system: RBMT21-129, RBMT21-350, RBMT22-082 |
| B-114 | Protecta _ | Potato | |
| B-115 | Russet?Burbank?NewLeaf _ | Potato | For example contain strain system: BT6, BT10, BT12, BT16, BT17, BT18, BT23 |
| B-116 | Clearfield _ | Sunflower | Non-transgenic has tolerance to imazamox |
| B-117 | Roundup?Ready _ | Wheat (Triticum aestivum) | MON71800 strain system |
| B-118 | Clearfield _ | Wheat | Non-transgenic has tolerance to imazamox |
| B-119 | Agrisure?3000GT | Corn (Zea mays L.) | CB/LL/RW/GT: by the synthetic Cry3A gene pairs glyphosate of GA21 strain system, Bt11 strain system, modification and the tolerance that careless fourth phosphine has |
| B-120 | Agrisure?CB/LL | Corn | Bt11 strain system adds the careless fourth phosphine tolerance of giving by GA21 strain system |
| B-86 | Agrisure?CB/LL/RW | Corn | Bt11 strain system, the synthetic Cry3A gene of modifying are by the tolerance of GA21 strain system to careless fourth phosphine |
| B-87 | Agrisure?CB/RW | Corn | The Cry3A of Bt11 strain system, Cry1Ab+MIR604 strain system, modification |
| B-88 | Agrisure?GT | Corn | Tolerance to glyphosate |
| B-89 | Agrisure?GT/CB/LL | Corn | By GA21 strain system, Bt11 strain is the tolerance to glyphosate and careless fourth phosphine |
| Sequence number | Trade (brand) name | Example | Describe |
| B-90 | Agrisure?GT/RW | Corn | To the tolerance of glyphosate, the synthetic Cry3A gene of modification |
| B-91 | Agristire?RW | Corn | MIR604 strain system, the synthetic Cry3A gene of modification |
| B-92 | Agrisure _(series) | Corn | BT11 strain system, Cry1Ab |
| B-93 | BiteGard _ | Corn | Cry1A (b) gene |
| B-94 | Bt-Xtra _ | Corn | The Cry1Ac gene |
| B-95 | Clearfield _ | Corn | Non-transgenic has tolerance to imazamox |
| B-96 | Herculex?I | Corn | TC1507 strain system, Cry1F |
| B-97 | Herculex?RW | Corn | DAS-59122-7 strain system, Cry34/35Ab1 |
| B-98 | Herculex?Xtra | Corn | TC1507 strain system+DAS 59122-7 strain system: Cry1F+ Cry34/35Ab1 (polymerization Bt corn (Bt corn stack)) |
| B-99 | Herculex?Xtra | Corn | TC1507 strain system+DAS 59122-7 strain system+NK603:Cry1F+ Cry 34/35Ab1 (polymerization Bt corn) |
| B-100 | Herculex _(series) | Corn | Insect had resistance |
| B-101 | IMI _ | Corn | Imidazolone had tolerance |
| B-102 | KnockOut _ | Corn | SYN-EV 176-9 strain system: cry1A (b) gene |
| B-103 | Mavera _ | Corn | High-lysine |
| B-104 | Na?tureGard _ | Corn | Cry1A (b) gene |
| B-105 | Roundup?Ready _ | Corn | GA21 strain system, NK603 strain system |
| Sequence number | Trade (brand) name | Example | Describe |
| B-106 | Roundup?Ready _?2 | Corn | For example the NK603 strain is |
| B-107 | SmartStax | Corn | Eight gene pyramidings of YieldGard VT Triple Pro, Herculex XTRA |
| B-108 | StarLink _ | Corn | The Cry9c gene |
| B-109 | STS _ | Corn | Sulfonylurea had tolerance |
| B-110 | YIELD?GARD _ | Corn | MON810 strain system, Cry1Ab |
| B-111 | YieldGard?Plus | Corn | Cry1Ab+Cry3Bb1 (polymerization Bt corn) |
| B-112 | YieldGard?Rootworm | Corn | MON863 strain system, Cry3Bb1 |
| B-113 | YieldGard?Rootworm?Ready?2 | Corn | MON810 strain system+NK603 strain system, Cry1Ab |
| B-114 | YieldGard?VT?Pro | Corn | MON89034 strain system/Cry 1A.105+Cry 2Ab2 |
| B-115 | YieldGard?VT?Rootworm | Corn | MON88017 strain system/Cry3Bb1 |
| B-116 | YieldGard?VT?Triple | Corn | MON88017 strain system/Cry3Bb1+Mon810 strain system, Cry1Ab |
| B-117 | YieldGard?VT?Triple?Pro | Corn | MON88017 strain system/Cry3Bb+MON89034 strain system/Cry1A.105+Cry2Ab2 |
| B-118 | YieldMaker TM | Corn | Comprise Roundup Ready 2 technology, YieldGard VT, YieldGard Corn Borer, YieldGard Rootworm and YieldGard Plus |
The useful especially genetically modified plants that can handle according to the present invention are the plant that contains the combination of transformation plant or transformation plant, these genetically modified plants be listed in the database of various countries for example or regional management organization (for example referring to
Http:// gmoinfo.jrc.it/gmp-browse.aspxWith http://www.agbios.com/dbase.php).
Other special genetically modified plant comprises the plant that contains agronomy neutrality or beneficial gene, described gene such as table among the C listed strain system description.
Table C
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-1 | ASR 368 | Creeping bentgrass (Agrosis stolonifera) | The 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of the modification by inserting coding Agrobacterium tumefaciems (Agrobacterium tumefacien) gene obtains glyphosate tolerant. |
| C-2 | H7-1 | Beet (sugar beet) | Produce glyphosate herbicidal tolerance sugar beet by 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) gene that inserts coding Agrobacterium tumefaciems CP4 bacterial strain. |
| C-3 | T120-7 | Beet (sugar beet) | Introduce the PPT transacetylase (PAT) of coding green color-producing streptomycete (Streptomyces viridochromogene)---a kind of aerobic soil bacteria---gene.PPT can suppress glutamine synthelase usually, causes the mortality accumulation of ammonia.Acetylizad PPT inactivation. |
| C-4 | GTSB77 | Beet (sugar beet) | Produce glyphosate herbicidal tolerance sugar beet by 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) gene that inserts coding Agrobacterium tumefaciems CP4 bacterial strain. |
| C-5 | 23-18-17,23-198 | Cabbage type rape (Argentinian rape) | Produce the rape of high laurate (12: 0) and myristinate (14: 0) content by inserting coding california laurel (California bay laurel) (California bay (Umbellularia the californica)) thioesterase of gene. |
| C-6 | 45A37,46A40 | Cabbage type rape (Argentinian rape) | Produce the rape of high oleic acid and low linolenic content by the backcross combination of (back-crossing) of the routine that high oleic acid content fatty acid desaturase is had optionally mutagenesis and introduce low content linolenic acid feature. |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-7 | 46A12,46A16 | Cabbage type rape (Argentinian rape) | Realize high oleic acid content feature mutagenesis and to the combination of the conventional breeding of registered rape variety. |
| C-8 | GT200 | Cabbage type rape (Argentinian rape) | The gene of the 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) by inserting coding Agrobacterium tumefaciems CP4 bacterial strain and the oxidasic gene of glyphosate of coding human pallid bacillus (Ochrobactrum anthropi) are produced glyphosate herbicidal tolerance rape. |
| C-9 | GT73, RT73 | Cabbage type rape (Argentinian rape) | Produce the rape of glyphosate tolerant weed killer herbicide by the oxidasic gene of glyphosate of 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) gene that inserts coding Agrobacterium tumefaciems CP4 bacterial strain and the human pallid bacillus of encoding. |
| C-10 | HCN10 | Cabbage type rape (Argentinian rape) | Introduce the PPT transacetylase (PAT) of the gene of coding green color-producing streptomycete---a kind of aerobic soil bacteria---.PPT can suppress glutamine synthelase usually, causes the mortality accumulation of ammonia.Acetylizad PPT inactivation. |
| C-11 | Topas 19/2 (HCN92) | Cabbage type rape (Argentinian rape) | Introduce the PPT transacetylase (PAT) of the gene of coding green color-producing streptomycete---a kind of aerobic soil bacteria---.PPT can suppress glutamine synthelase usually, causes the mortality accumulation of ammonia.Acetylizad PPT inactivation. |
| C-12 | MS1, RF1=＞PGS1 | Cabbage type rape (Argentinian rape) | The pollination hierarchy of control of male sterile, fertility restorer, demonstration grass ammonium phosphine herbicide tolerant.The RF system that the barster gene of the contained MS of the barnase gene of bacillus amyloliquefaciens (Bacillus amyloliquefaciens) system, bacterium of the same race is contained and two be c. |
| C-13 | MS1, RF2=＞PGS2 | Cabbage type rape (Argentinian rape) | The pollination hierarchy of control of male sterile, fertility restorer, demonstration grass ammonium phosphine herbicide tolerant.Separate |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| The RF system that the barster gene of the contained MS of the barnase gene of bacillus amyloliquefaciens system, bacterium of the same race is contained and two be c. | |||
| C-14 | MS8 * RF3 | Cabbage type rape (Argentinian rape) | The pollination hierarchy of control of male sterile, fertility restorer, demonstration grass ammonium phosphine herbicide tolerant.The MS system that the barnase gene of bacillus amyloliquefaciens is contained, the contained RF of the barster gene of bacterium of the same race is and is two is c. |
| C-15 | NS738, NS1471, NS1473 | Cabbage type rape (Argentinian rape) | The selection of the altered somaclonal variation body of the acetolactate synthase after the mutagenesis (ALS).Initial selection two is that (P1 P2) locates to modify at different unlinked geneses site (unlinked loci).NS738 only contains the P2 sudden change. |
| C-16 | OXY-235 | Cabbage type rape (Argentinian rape) | Form tolerance by the nitrilase gene (oxy) of introducing Friedlander (Klebsiella pneumoniae) to weed killer herbicide Brominal and ioxynil. |
| C-17 | MS8 | Cabbage type rape (Argentinian rape) | Feature: glufosinate tolerant, male sterile gene: bar, barnase |
| C-18 | PHY14, PHY35 | Cabbage type rape (Argentinian rape) | Male sterile forms by the barnase ribonuclease gene that inserts bacillus amyloliquefaciens; Fertility restorer forms by the ribonuclease inhibitor that inserts barstar; The PPT resistance forms by the PPT-transacetylase (PAT) of streptomyces hygroscopicus (Streptomyces hygroscopicus). |
| C-19 | PHY36 | Cabbage type rape (Argentinian rape) | Male sterile forms by the barnase ribonuclease gene that inserts bacillus amyloliquefaciens; Fertility restorer forms by the ribonuclease inhibitor that inserts barstar; The PPT resistance forms by the PPT-transacetylase (PAT) of streptomyces hygroscopicus. |
| C-20 | RF1, (B93-101) | Cabbage type rape (Argentinian rape) | Gene: bar, barstar, neomycin phosphotransferase II (npt II); |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| Feature: fertility restorer, glufosinate tolerant, kanamycin (Kanamycin) resistance | |||
| C-21 | RF2, (B94-101) | Cabbage type rape (Argentinian rape) | Gene: bar, barstar, neomycin phosphotransferase II (nptII); Feature: fertility restorer, glufosinate tolerant, kalamycin resistance |
| C-22 | RF3, ACS-BN Φ Φ 3-6 | Cabbage type rape (Argentinian rape) | Feature: fertility restorer, glufosinate tolerant; Gene: bar, barstar |
| C-23 | MS1 (B91-4) | Cabbage type rape (Argentinian rape) | Feature: glufosinate tolerant, kalamycin resistance, male sterile; Gene: bar, barnase, neomycin phosphotransferase II (nptII) |
| C-24 | T45 (HCN28) | Cabbage type rape (Argentinian rape) | The introducing of the PPT transacetylase (PAT) of coding green color-producing streptomycete---a kind of aerobic soil bacteria---gene.PPT can suppress glutamine synthelase usually, causes the mortality accumulation of ammonia.Acetylizad PPT inactivation. |
| C-25 | HCR-1 | Turnip (Polish rape (polish canola)) | From the transgenosis cabbage type rape is the feature of introducing careless ammonium phosphine herbicide tolerant among the T45.This feature is by careless fourth phosphinothricin acetyl transferase (PAT) mediation of the gene of coding green color-producing streptomycete. |
| C-26 | ZSR500/502 | Turnip (Polish rape) | The 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) that introduce to modify and the gene of achromobacter (Achromobacter sp), this achromobacter can be degraded to aminomethyl phosphonic acids (aminomethylphosphonic acid) (AMPA) and by carrying out interspecific cross and degrade acetaldehyde acid with GT73 with glyphosate by conversion. |
| C-27 | 55-1/63-1 | Papaya papaw (Carica papaya) | The papaya papaw of PRSV (PRSV) resistance that the coat protein (CP) of the marmor upsilon group sequence by inserting this plant of coding is produced. |
| C-28 | RM3-3, RM3-4, | Witloof | Male sterile is by the ribose nuclear of the barstar of insertion bacillus amyloliquefaciens |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| RM3-6 | Phytase gene and forming; The PPT resistance forms by the bar gene of streptomyces hygroscopicus, this streptomyces hygroscopicus coding PAT enzyme. | ||
| C-29 | A, B | Muskmelon (Cucumis melo) | By the gene of introducing coding S-adenosylmethionine (SAM) hydrolase, thereby reduced the accumulation of S-adenosylmethionine and reduced the synthetic of ethene. |
| C-30 | CZW-3 | Custard squash (Cucurbita pepo) | Cucumber mosaic virus (cucumber mosiac virus) (CMV), little zucchini yellow mosaic virus (zucchini yellows mosaic virus) (ZYMV) and watermelon mosaic virus (watermelon mosaic virus) (MWV) coat protein (CP) of 2 type resistance pumpkins (custard squash) by each described plant virus sequence of will encoding insert host genome and produce. |
| C-31 | ZW20 | Custard squash | Little zucchini yellow mosaic virus (ZYMV) and watermelon mosaic virus (MWV) 2 type resistance pumpkins (custard squash) insert host genome by the coat protein (CP) of the marmor upsilon group sequence of each described plant of will encoding and produce. |
| C-32 | 66 | Carnation (Dianthus caryophyllus) | Truncation copy (truncated copy) the production capacity delay senility in next life of carnation amino-cyclopropane cyclase (ACC) synzyme by inserting encoding gene and the carnation of sulfonylurea herbicide tolerance, so that suppress the unmodified expression of gene of endogenous, the unmodified gene of this endogenous is re |
| C-33 | 4,11,15,16 | Carnation | By inserting the carnation of two kinds of anthocyan (anthocyain) biosynthesis gene production capacity in next life change color and sulfonylurea herbicide tolerance, the expression of anthocyan biosynthesis gene causes purple/aubergine painted.Need by introducing the tolerance of chlorine sulphur grand (chlorsulfuro) formation sulfonylurea herbicide. |
| C-34 | 11363 | Carnation | Feature: painted; Gene als (genes als), flavanonol reductase (dihydroflavonol |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| Reductase) (dfr), flavonoids 3 ', 5 ' hydroxylase (F3 ' 5 ' H) | |||
| C-35 | 959A, 988A, 1226A, 1351A, 1363A, 1400A | Carnation | Introduce two kinds and can produce the painted anthocyan biosynthesis gene of purple/aubergine; Introduce the variant that forms acetolactate synthase (ALS). |
| C-36 | 123.2. (40619) | Carnation | Feature: painted; Gene als, flavanonol reductase (dfr), flavonoids 3 ', 5 ' hydroxylase (F3 ' 5 ' H) |
| C-37 | 123.8.8 (40685) | Carnation | |
| C-38 | 11 (7442) | Carnation | |
| C-39 | A2704-12, A2704-21, A5547-35 | Soybean | The modification grass fourth phosphinothricin acetyl transferase (PAT) of the gene by inserting coding soil bacteria green color-producing streptomycete is produced careless ammonium phosphine herbicide tolerant soybean. |
| C-40 | A5547-127 | Soybean | The modification grass fourth phosphinothricin acetyl transferase (PAT) of the gene by inserting coding soil bacteria green color-producing streptomycete is produced careless ammonium phosphine herbicide tolerant soybean. |
| C-41 | G94-1, G94-19, G168 | Soybean | The soybean that the another copy of the fatty acid desaturase (GmFad2-1) of the gene by introducing the coding soybean is produced high oleic acid content, this insertion causes " silence " of endogenous host gene. |
| C-42 | GTS 40-3-2 | Soybean | The 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of the modification of the gene by inserting coding soil bacteria Agrobacterium is produced glyphosate tolerant soybean variant. |
| C-43 | GU262 | Soybean | The careless fourth phosphinothricin acetyl transferase (PAT) of the modification of the gene by inserting coding soil bacteria green color-producing streptomycete is produced careless ammonium phosphine herbicide tolerant soybean. |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-44 | MON89788 | Soybean | The 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of the modification of aroA (epsps) gene by inserting coding Agrobacterium CP4 is produced the glyphosate tolerant soybean. |
| C-45 | OT96-15 | Soybean | Include the soybean that the naturally occurring new feature that can form the fan 1 type gene mutation body of low linolenic content is produced low linolenic content in by the conventional hybridization breeding. |
| C-46 | W62, W98 | Soybean | The careless fourth phosphinothricin acetyl transferase (PAT) of the modification of the gene by inserting coding soil bacteria streptomyces hygroscopicus is produced careless ammonium phosphine herbicide tolerant soybean. |
| C-47 | 15985 | Upland cotton (cotton) | Conversion by DP50B parent variant obtains insect resistant cotton, this DP50B parent variant contains strain and is 531 (expressing the Cry1Ac protein), and strain is 531 to have the plasmid DNA of the purifying of the cry2Ab gene that contains bacillus thuringiensis,Bt Kustak subspecies (subsp.kurstaki). |
| C-48 | 19-51A | Upland cotton (cotton) | Introduce the variant that forms acetolactate synthase (ALS). |
| C-49 | 281-24-236 | Upland cotton (cotton) | Produce insect resistant cotton by the cry 1F gene that inserts bacillus thuringiensis,Bt mutation aizawai.The PAT of the gene of coding green color-producing streptomycete is introduced into as selected marker. |
| C-50 | 3006-210-23 | Upland cotton (cotton) | Produce insect resistant cotton by the cry1Ac gene of introducing bacillus thuringiensis,Bt Kustak subspecies.The PAT of the gene of coding green color-producing streptomycete is introduced into as selected marker. |
| C-51 | 31807/31808 | Upland cotton (cotton) | Produce insect-resistant and Buctril Industrial tolerance cotton by the cry1Ac gene that inserts bacillus thuringiensis,Bt with the nitrilase of the gene of coding Klebsiella Pneumoniae. |
| C-52 | BXN | Upland cotton (cotton) | The nitrilase of the gene by inserting the coding Klebsiella Pneumoniae is produced Buctril Industrial tolerance cotton. |
| C-53 | COT102 | Upland cotton (cotton) | Produce insect resistant cotton by vip3A (a) gene that inserts bacillus thuringiensis,Bt AB88.Compile |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| The APH4 of the gene of sign indicating number Escherichia coli (E.coli) is introduced into as selected marker. | |||
| C-54 | DAS-21 Φ 23-5 * DAS-24236-5 | Upland cotton (cotton) | WideStrike TM, a kind of multiple (stacked) insect resistant cotton, by the parent be 3006-210-23 (the OECD identifier: DAS-21 Φ 23-5) and 281-24-236 (the OECD identifier: conventional hybridization breeding DAS-24236-5) obtains. |
| C-55 | DAS-21 Φ 23-5 * DAS-24236-5 * MON88913 | Upland cotton (cotton) | (the OECD identifier: DAS-21 Φ 23-5 * DAS-24236-5) (the OECD identifier: conventional hybridization breeding MON-Φ 1445-2) obtains with the MON88913 that is called RoundupReady Flex by the WideStrike cotton for multiple insect-resistant and glyphosate tolerant cotton. |
| C-56 | DAS-21 Φ 23-5 * DAS-24236-5 * MON-Φ 1445-2 | Upland cotton (cotton) | WideStrike TM/ Roundup Ready_ cotton, a kind of multiple insect-resistant and glyphosate tolerant cotton, (the OECD identifier: DAS-21 Φ 23-5 * DAS-24236-5) (the OECD identifier: conventional hybridization breeding MON-Φ 1445-2) obtains with MON1445 by the WideStrike cotton. |
| C-57 | LLCotton25 | Upland cotton (cotton) | The careless fourth phosphinothricin acetyl transferase (PAT) of the modification of the gene by inserting coding soil bacteria streptomyces hygroscopicus is produced careless ammonium phosphine herbicide tolerant cotton. |
| C-58 | LLCotton25 * MON15985 | Upland cotton (cotton) | ACS-GH Φ Φ 1-3) multiple herbicide tolerant and insect resistant cotton have been incorporated LLCotton25 (OECD identifier: to the tolerance of careless ammonium phosphine weed killer herbicide and MON1598 (OECD identifier: MON-15985-7) to the tolerance of insect into. |
| C-59 | MON1445/1698 | Upland cotton (cotton) | The natural glyphosate tolerant form of the 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) by inserting agrobacterium strains CP4 is produced glyphosate herbicidal tolerance cotton. |
| C-60 | MON15985 * | Upland cotton (cotton) | Multiple insect-resistant and glyphosate tolerant cotton are MON88913 (OECD sign by the parent |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| MON88913 | Symbol: (OECD identifier: conventional hybridization breeding MON-15985-7) and obtaining MON-88913-8) with 15985. | ||
| C-61 | MON-15985-7 * MON-Φ 1445-2 | Upland cotton (cotton) | Multiple insect-resistant and herbicide tolerant cotton are that (the OECD identifier: MON-15985-7) (the OECD identifier: conventional hybridization breeding MON-Φ 1445-2) obtains MON15985 with MON1445 by the parent. |
| C-62 | MON531/757/1076 | Upland cotton (cotton) | Produce insect resistant cotton by the cry1Ac gene that inserts bacillus thuringiensis,Bt Kustak subspecies HD-73 (B.t.k.). |
| C-63 | MON88913 | Upland cotton (cotton) | Two genes of the 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) by inserting coding Agrobacterium CP4 bacterial strain are produced glyphosate herbicidal tolerance cotton. |
| C-64 | MON-Φ Φ 531-6 * MON-Φ 1445-2 | Upland cotton (cotton) | Multiple insect-resistant and herbicide tolerant cotton are that (the OECD identifier: MON-Φ Φ 531-6) (the OECD identifier: conventional hybridization breeding MON-Φ 1445-2) obtains MON531 with MON1445 by the parent. |
| C-65 | T304-40 | Upland cotton (cotton) | Give the gene element of phenotype insect-resistant and careless ammonium phosphine herbicide tolerant :-cry1: coding gives cry gene order-bar of the bacillus thuringiensis,Bt of insect-resistant feature: coding phosphino-(phosphinoth) sequence. |
| C-66 | GHB714 | Upland cotton (cotton) | Give the gene element of phenotype insect-resistant and careless ammonium phosphine herbicide tolerant :-cry2: coding gives cry gene order-bar of the bacillus thuringiensis,Bt of insect-resistant feature: coding phosphino-sequence. |
| C-67 | GHB119 | Upland cotton (cotton) | Give the gene element of phenotype insect-resistant and careless ammonium phosphine herbicide tolerant: |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| -cry2: coding gives cry gene order-bar of the bacillus thuringiensis,Bt of insect-resistant feature: coding phosphino-sequence. | |||
| C-68 | T303-3 | Upland cotton (cotton) | -cry1: coding gives the cry gene order-bar of bacillus thuringiensis,Bt of insect-resistant feature: coding gives gene (bar) sequence of careless fourth phosphinothricin acetyl transferase of the streptomyces hygroscopicus of Herbicid resistant feature. |
| C-69 | GHB614 | Upland cotton (cotton) | 2mepsps: coding gives the 2mepsps sequence of the corn of glyphosate herbicidal resistance feature. |
| C-70 | X81359 | Sunflower (Helianthus annuus) | By selecting naturally occurring mutant that imidazolone is had tolerance. |
| C-71 | RH44 | Lens culinaris (Lens culinaris) | Select acetohydroxy acid synthetase (AHAS), be also referred to as the mutant variant that acetolactate synthase (ALS) or acetolactic acid pyruvate split synzyme (acetolactate pyruvate-lyase). |
| C-72 | FP967 | Flax (Linum usitatissimum L.) (linseed) | The variant form of acetolactate synthase (ALS) obtains from chlorine sulphur grand (chlorsulfuron) the tolerance system of arabidopsis (A.thaliana), and is used to transform flax. |
| C-73 | 5345 | Tomato (Lycopersicon esculentum) | Has resistance by the cry1Ac gene pairs lepidoptera pest of introducing bacillus thuringiensis,Bt Kustak subspecies. |
| C-74 | 8338 | Tomato | Introduce the gene order of the 1-amino-cyclopropane-1-carboxylic acid deaminase (ACCd) of coding metabolism fruit maturation hormone precursor. |
| C-75 | 1345-4 | Tomato | Other copy production of truncation gene by inserting coding 1-amino-cyclopropane-1-carboxylic acid (ACC) synzyme delays ripe tomato, the accumulation that this can cause the downward modulation of endogenous ACC synzyme and reduce ethene. |
| C-76 | 35 1N | Tomato | Introduce the base of the S-adenosylmethionine hydrolase of coding metabolism fruit maturation hormone ethene precursor |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| Because of sequence. | |||
| C-77 | B, Da, F | Tomato | Reduce endogenous PG gene expression and produce at the truncation variant of the polygalacturonase (PG) of justice (in the sense) or antisense (anti-sense) direction encoding gene and to postpone softening tomato by being inserted as, thereby reduced the degraded of pectin. |
| C-78 | FLAVR SAVR | Tomato | Reduce endogenous PG gene expression and produce at other copy of the polygalacturonase (PG) of antisense orientation encoding gene and to postpone softening tomato by being inserted as, thereby reduced the degraded of pectin. |
| C-79 | J101, J163 | Lucerne (clover) | The gene of the 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) by introducing coding Agrobacterium CP4 bacterial strain is produced glyphosate herbicidal tolerance clover (alfalfa). |
| C-80 | C/F/93/08-02 | Tobacco (Nicotiana tabacum L) | Has herbicide tolerant by the nitrilase gene of introducing Klebsiella Pneumoniae to Brominal and ioxynil. |
| C-81 | Vector 21-41 | Tobacco | Reduce nicotine content by the another copy of introducing tobacco QPRT (QTPase) at antisense orientation.The NPT II of coding bacillus coli gene is introduced into as the selected marker that identification transforms. |
| C-82 | CL121, CL141, CFX51 | Rice | By (induce) the tolerance of inducting with ethylmethane sulfonate (EMS) (ethyl methanesulfonate) mutagenesis acetolactate synthase (ALS) to imidazolidinone weedicide Imazethapyr (imazethapyr). |
| C-83 | IMINTA-1, IMINTA-4 | Rice | By inducting to the tolerance of imidazolidinone weedicide with sodium azide mutagenesis acetolactate synthase (ALS). |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-84 | LLRICE06, LLRICE62 | Rice | Produce careless ammonium phosphine herbicide tolerant rice by the modification transacetylase (PAT) of introducing coding soil bacteria streptomyces hygroscopicus gene. |
| C-85 | LLRICE601 | Rice | Produce careless ammonium phosphine herbicide tolerant rice by the modification transacetylase (PAT) of introducing coding soil bacteria streptomyces hygroscopicus gene. |
| C-86 | PWC16 | Rice | By inducting to the tolerance of imidazolidinone weedicide Imazethapyr with ethylmethane sulfonate (EMS) mutagenesis acetolactate synthase (ALS). |
| C-87 | ATBT04-6, ATBT04-27, ATBT04-30, ATBT04-31, ATBT04-36, SPBT02-5, SPBT02-7 | Potato | Produce the potato of colorado potato beetle (colorado potato beetle) resistance by the cry3A gene that inserts bacillus thuringiensis,Bt (Kustak subspecies). |
| C-88 | BT6, BT10, BT12, BT16, BT17, BT18, BT23 | Potato | Produce the potato of colorado potato beetle resistance by the cry3A gene that inserts bacillus thuringiensis,Bt (Kustak subspecies). |
| C-89 | RBMT15-101, SEMT15-02, SEMT15-15 | Potato | Produce the potato of colorado potato beetle and marmor upsilon group (PVY) resistance by the coat protein of the cry3A gene of insertion bacillus thuringiensis,Bt (Kustak subspecies) and the PVY gene of encoding. |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-90 | RBMT21-129, RBMT21-350, RBMT22-082 | Potato | The replicase of cry3A gene by inserting bacillus thuringiensis,Bt (Kustak subspecies) and the gene of coding PLRV is produced (PLRV) potato of resistance of colorado potato beetle and corium solani (potato leafroll virus). |
| C-91 | AM02-1003, AM01-1005 AM02-1012 AM02-1017 AM99-1089 and AM99-2003 | Potato | A) contain the gene of potato gbss code area (coding region) at the relative antisense orientation of precursor, polyadenylic acidization (polyadenylation) the sequence side by potato gbss precursor and Agrobacterium nopaline (nopaline) synthase gene place joins. |
| C-92 | EH92-527-1 | Potato | In the potato strain is among the EH92-527-1, contains the gene of potato gbss (particle mating type amylosynthease) precursor---in fragment with respect to the potato gbss code area of the antisense orientation of the polyadenylic acid sequences of precursor and Agrobacterium tumefaciens (Agrobacterium tu). |
| C-93 | AP205CL | Wheat | Select acetohydroxy acid synthetase (AHAS), be also referred to as the mutant variant that acetolactate synthase (ALS) or acetolactic acid pyruvate split synzyme. |
| C-94 | AP602CL | Wheat | Select acetohydroxy acid synthetase (AHAS), be also referred to as the mutant variant that acetolactate synthase (ALS) or acetolactic acid pyruvate split synzyme. |
| C-95 | BW255-2, BW238-3 | Wheat | Select acetohydroxy acid synthetase (AHAS), be also referred to as the mutant variant that acetolactate synthase (ALS) or acetolactic acid pyruvate split synzyme. |
| C-96 | MON71800 | Wheat | The modification 5-enol pyruvoyl of the gene by inserting coding soil bacteria agrobacterium strains CP4 is big |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| Oxalic acid-3-phosphate synthase (EPSPS) is produced glyphosate tolerant wheat variant. | |||
| C-97 | SWP965001 | Wheat | Select acetohydroxy acid synthetase (AHAS), be also referred to as the mutant variant that acetolactate synthase (ALS) or acetolactic acid pyruvate split synzyme. |
| C-98 | DW2, DW6, DW12 | Wheat | |
| C-99 | BW7 | Wheat | The imidazolidinone weedicide tolerance. |
| C-10 O | Teal 11A | Wheat | Select acetohydroxy acid synthetase (AHAS), be also referred to as the mutant variant that acetolactate synthase (ALS) or acetolactic acid pyruvate split synzyme. |
| C-10 1 | 176 | Corn | Produce the insect-resistant corn by the cry1Ab gene that inserts bacillus thuringiensis,Bt Kustak subspecies.This gene modification provides the resistance to European corn borer (ECB) invasion and attack. |
| C-10 2 | 3751IR | Corn | Be chosen in the somatocyte allosome-changing of cultivating the embryo on the medium that contains imidazolone. |
| C-1O 3 | 676,678,680 | Corn | Gene by inserting the adenine methylase DNA that encodes respectively and Escherichia coli and green color-producing streptomycete the gene of careless fourth phosphinothricin acetyl transferase (PAT) come production male sterile and careless ammonium phosphine herbicide tolerant corn. |
| C-10 4 | ACS-ZM Φ Φ 3-2 * MON-Φ Φ 81 Φ-6 | Corn | The hybrid corn of multiple insect-resistant and herbicide tolerant by the parent be T25 (the OECD identifier: ACS-ZM Φ Φ 3-2) and MON810 (the OECD identifier: conventional hybridization breeding MON-Φ Φ 81 Φ-6) obtains. |
| C-10 5 | B16 (DLL25) | Corn | The gene of the careless fourth phosphinothricin acetyl transferase (PAT) by inserting the coding streptomyces hygroscopicus is produced careless ammonium phosphine herbicide tolerant corn. |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-10 6 | BT11 (X4334CBR, X4734CBR) | Corn | Produce insect-resistant and herbicide tolerant corn by the cry1Ab gene that inserts bacillus thuringiensis,Bt Kustak subspecies with the careless fourth phosphinothricin acetyl transferase (PAT) of the gene of coding green color-producing streptomycete. |
| C-10 7 | CBH-351 | Corn | The gene of Cry9C albumen by inserting coding bacillus thuringiensis,Bt many nests subspecies (subsp tolworthi) and the careless fourth phosphinothricin acetyl transferase (PAT) of streptomyces hygroscopicus is produced insect-resistant and careless ammonium phosphine herbicide tolerant corn. |
| C-10 8 | DAS-06275-8 | Corn | Produce lepidopterous insects resistance and careless ammonium phosphine herbicide tolerant corn by the cry1F gene of insertion coding bacillus thuringiensis,Bt mutation aizawai and the careless fourth phosphinothricin acetyl transferase (PAT) of streptomyces hygroscopicus. |
| C-10 9 | DAS-59122-7 | Corn | Produce corn by the cry34Ab1 and the cry35Ab1 gene that insert bacillus thuringiensis strains Ps149B1 with pumpkin 12 asterophyllite first resistances.The PAT of the gene of coding green color-producing streptomycete is introduced into as selected marker. |
| C-11 0 | DAS-59122-7 * NK603 | Corn | By the parent be DAS-59122-7 (the OECD unique identifier: DAS-59122-7) and NK603 (the OECD unique identifier: multiple insect-resistant and herbicide tolerant corn are produced in conventional hybridization breeding MON-Φ Φ 6 Φ 3-6).The corn of pumpkin 12 asterophyllite first resistances is obtained by DA. |
| C-11 1 | DAS-59122-7 * TC1507 * NK603 | Corn | By the parent be DAS-59122-7 (the OECD unique identifier: DAS-59122-7) and TC1507 (the OECD unique identifier: DAS-Φ 15 Φ 7-1) (the OECD unique identifier: multiple insect-resistant and herbicide tolerant are produced in conventional hybridization breeding MON-Φ Φ 6 Φ 3-6) with NK603 |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| The property corn. | |||
| C-11 2 | DAS-Φ 15 Φ 7-1 * MON-Φ Φ 6 Φ 3-6 | Corn | DAS-Φ 15 Φ 7-1) and NK603 (OECD identifier: conventional hybridization breeding MON-Φ Φ 6 Φ 3-6) and obtaining multiple insect-resistant and herbicide tolerant hybrid corn are by parent's (OECD identifier: that is 1507. |
| C-11 3 | DBT418 | Corn | The gene of the careless fourth phosphinothricin acetyl transferase (PAT) by inserting coding bacillus thuringiensis,Bt Kustak subspecies Cry1AC albumen and streptomyces hygroscopicus is cultivated has insect-resistant and careless ammonium phosphine herbicide tolerant corn. |
| C-11 4 | DK404SR | Corn | Be chosen in the somatocyte allosome-changing of cultivating embryo's the acetyl-CoA carboxylase with modification (ACCase) on the medium that is rich in sethoxydim (sethoxydim). |
| C-11 5 | EXP1910IT | Corn | By inducting to the tolerance of imidazolidinone weedicide Imazethapyr (imazethapyr) with ethylmethane sulfonate (EMS) mutagenesis acetolactate synthase (ALS). |
| C-11 6 | GA21 | Corn | Introduce the 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of modification by particle bombardment (particle bombardment)---contained a kind of enzyme in shikimic acid (shikimate) biochemical pathway of producing aromatic amino acid. |
| C-11 7 | IT | Corn | External selection by somatocyte allosome-changing obtains the tolerance to the imidazolidinone weedicide Imazethapyr. |
| C-11 8 | LY038 | Corn | Make amino acid composition change, especially improve by the cordapA gene of introducing coding dihydrodipicolinic acid synthase (dihydrodipicolinase synthase) corynebacterium glutamicum (Corynebacterium glutamicum) (cDHDPS) |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| Lysine content. | |||
| C-11 9 | MIR604 | Corn | Produce pumpkin 12 asterophyllite first resistance corns by being converted of modification cry3A gene.Colibacillary phosphomannose isomerase (phosphomannose isomerase) gene is used as selected marker. |
| C-12 0 | MON80100 | Corn | Produce the corn of insect-resistant by the cry1Ab gene that inserts bacillus thuringiensis,Bt Kustak subspecies.This gene modification provides the resistance to European corn borer (ECB) invasion and attack. |
| C-12 1 | MON802 | Corn | The gene of the Cry1Ab albumen by inserting the coding bacillus thuringiensis,Bt and 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of agrobacterium strains CP4 is produced insect-resistant and glyphosate herbicidal tolerance corn. |
| C-12 2 | MON809 | Corn | By introducing synthetic gene cry1Ab European corn borer (corn borer) had resistance.Bacterium variant by introduced plant enzyme 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) has glyphosate resistance. |
| C-12 3 | MON810 | Corn | The cry1Ab gene of the truncation form by inserting bacillus thuringiensis,Bt Kustak subspecies HD-1 is produced the corn of insect-resistant.This gene modification provides the resistance to European corn borer (ECB) invasion and attack. |
| C-12 4 | MON810 * MON88017 | Corn | MON-Φ Φ 81 Φ-6) and MON88017 (OECD identifier: conventional hybridization breeding MON-88 Φ 17-3) and obtaining the corn of multiple insect-resistant and glyphosate tolerant is a MON810 (OECD identifier: by the parent.European corn borer (ECB) resistance by ... and obtain. |
| C-12 | MON832 | Corn | Introduce the 5-enol pyruvoyl shikimic acid of glyphosate oxidase (GOX) and modification by particle bombardment |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| 5 | -3-phosphate synthase (EPSPS), described EPSPS are contained a kind of enzyme in shikimic acid (shikimate) biochemical pathway of producing aromatic amino acid. | ||
| C-12 6 | MON863 | Corn | Produce by the cry3Bb1 gene that inserts bacillus thuringiensis,Bt subspecies kumamotoensis and to have pumpkin 12 asterophyllite first resistance corns. |
| C-12 7 | MON88017 | Corn | Produce pumpkin 12 asterophyllite first resistance corns by the cry3Bb1 gene that inserts bacillus thuringiensis,Bt subspecies kumamotoensis bacterial strain EG4691.Obtain glyphosate tolerant by 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of introducing coding Agrobacterium gene. |
| C-12 8 | MON-Φ Φ 6 Φ 3-6 * MON-Φ Φ 81 Φ-6 | Corn | MON-Φ Φ 6 Φ 3-6) and MON810 (OECD identifier: conventional hybridization breeding MON-Φ Φ 81 Φ-6) and obtaining the hybrid corn of multiple insect-resistant and glyphosate tolerant is a NK603 (OECD identifier: by the parent. |
| C-12 9 | MON-Φ Φ 81 Φ-6 * LY038 | Corn | MON-Φ Φ 81 Φ-6) and LY038 (OECD identifier: conventional hybridization breeding REN-Φ Φ Φ 38-3) and obtaining the corn of the lysine content of multiple insect-resistant and raising is a MON810 (OECD identifier: by the parent. |
| C-13 0 | MON-Φ Φ 863-5 * MON-Φ Φ 6 Φ 3-6 | Corn | MON-Φ Φ 863-5) and NK603 (OECD identifier: conventional hybridization breeding MON-Φ Φ 6 Φ 3-6) and obtaining the hybrid corn of multiple insect-resistant and glyphosate tolerant is a MON863 (OECD identifier: by the parent. |
| C-13 1 | MON-Φ Φ 863-5 * MON-Φ Φ 81 Φ-6 | Corn | MON-Φ Φ 863-5) and MON810 (OECD identifier: conventional hybridization breeding MON-Φ Φ 81 Φ-6) and obtaining the hybrid corn of multiple insect-resistant is a MON863 (OECD identifier: by the parent. |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-13 2 | MON-Φ Φ 863-5 * MON-Φ Φ 81 Φ-6 * MON-Φ Φ, 6 Φ 3-6 | Corn | The hybrid corn of multiple insect-resistant and herbicide tolerant is by multiple hybrid MON-Φ Φ 863-5 * MON-Φ Φ 81 Φ-6 and NK603 (OECD identifier: conventional hybridization breeding MON-Φ Φ 6 Φ 3-6) and obtaining. |
| C-13 3 | MON-Φ Φ Φ 21-9 * MON-Φ Φ 81 Φ-6 | Corn | MON-Φ Φ Φ 21-9) and MON810 (OECD identifier: conventional hybridization breeding MON-Φ Φ 81 Φ-6) and obtaining the hybrid corn of multiple insect-resistant and herbicide tolerant is a GA21 (OECD identifier: by the parent. |
| C-13 4 | MS3 | Corn | Male sterile forms by the expression of the barnase ribonuclease gene of bacillus amyloliquefaciens; The PPT resistance forms by PPT-transacetylase (PAT). |
| C-13 5 | MS6 | Corn | Male sterile forms by the expression of the barnase ribonuclease gene of bacillus amyloliquefaciens; The PPT resistance forms by PPT-transacetylase (PAT). |
| C-13 6 | NK603 | Corn | By the 5-enol pyruvoyl shikimic acid-3-phosphate synthase (EPSPS) of particle bombardment introducing modification, described EPSPS is contained a kind of enzyme in shikimic acid (shikimate) biochemical pathway of producing aromatic amino acid. |
| C-13 7 | SYN-BT Φ 11-1 * MON-Φ Φ Φ 21-9 | Corn | By the parent be BT11 (the OECD unique identifier: SYN-BT Φ 11-1) and GA21 (the OECD unique identifier: multiple insect-resistant and herbicide tolerant corn are produced in conventional hybridization breeding MON-Φ Φ Φ 21-9). |
| C-13 8 | T14, T25 | Corn | The careless fourth phosphine N-acetyl-transferase (PAT) of the gene by inserting coding aerobic actinomycetes (actinomycete) green color-producing streptomycete is produced careless ammonium phosphine herbicide tolerant corn. |
| C-13 | TC1507 | Corn | By cry 1F gene and the green look strepto-that produces of coding that inserts bacillus thuringiensis,Bt mutation aizawai |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| 9 | The careless fourth phosphine N-acetyl-transferase of bacterium gene is produced insect-resistant and careless ammonium phosphine herbicide tolerant corn. | ||
| C-14 0 | TC1507 * DAS-59122-7 | Corn | By the parent be TC1507 (the OECD unique identifier: DAS-Φ 15 Φ 7-1) and DAS-59122-7 (the OECD unique identifier: multiple insect-resistant and herbicide tolerant hybrid corn are produced in conventional hybridization breeding DAS-59122-7).The lepidopterous insects resistance by ... and obtain. |
| C-14 1 | SYTGA21 | Corn | The glyphosate herbicidal tolerance |
| C-14 2 | SYTGA21+Bt11 | Corn | The corn borer prevention effect glyphosate herbicidal tolerance of Cry1Ab |
| C-14 3 | MON810+SYTGA21 | Corn | The corn borer resistance glyphosate herbicidal tolerance of Cry1Ab |
| C-14 4 | MON89034 | Corn | Comprehensive description of the gene element among the MON 89034 is provided in the table 1, has comprised its approx. dimension, source and function.The general introduction of the gene element that inserts among the table 1.MON 89034.B1-left margin (B1-Left Border) *: the 239bp DNA zone that is different from B Left Bord |
| C-14 5 | MON89034 * MON88017 | Corn |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-14 6 | MON89034 * NK603 | Corn | |
| C-14 7 | DP-Φ 9814 Φ-6 | Corn | The adjustment element (regulatory element) of gene expression and the modification in corn acetolactate synthase (zm-hra) gene by inserting glyphosate-N-acetyl-transferase (gat4621) gene and modification and the necessary milpa usually of 98140 corns. |
| C-14 8 | 3243M | Corn | Adjust sequence: the precursor sequence that comes from corn.The function of these sequences is to be used to control the insect-resistant expression of gene.The insect-resistant gene: the function that comes from these sequences of cry1Ab gene of bacillus thuringiensis,Bt is to be used for ... |
| C-14 9 | DP-444 BG/RR | Upland cotton (cotton) | Bollgard/RoundupReady from US 2003213029-A1 |
| C-15 0 | VSN-BTCRW | Corn | Bt toxin pumpkin 12 asterophyllite first |
| C-15 1 | HCL201CRW2RR× LH324 | Corn | Bt toxin pumpkin 12 asterophyllite first |
| C-15 2 | LH324 | Corn | From US 7223908 B1 |
| Sequence number | Strain system | Crop | One or more features behind the genetic modification |
| C-15 3 | VSN-RRBt | Corn | RoundupReady Bt toxin |
| C-15 4 | FR1064LL× FR2108 | Corn | List of references: Gerdes, J.T., Behr, C.F., Coors, J.G., and Tracy W.F.1993.Compilation of North American Maize Breeding Germplasm.W.F.Tracy.J.G.Coors, and J.L.Geadelmann, eds.Crop Science Society of America, Madison, WI and US 6407320 B1 |
| C-15 5 | VSN-Bt | Corn | The Bt toxin |
The invention provides the composition that contains bond of the present invention on the other hand.Preferred sterilization and/or Pesticidal combination contain agricultural and go up acceptable additive, solvent, carrier, surfactant or filler.
According to the present invention, natural or synthetic, the organic or inorganic compound of term " carrier " expression, the reactive compound A of formula (I) and compd B combine with this compound or associate and make it be easier to use, and particularly impose on plant parts.Therefore the preferred inertia of this carrier and should be at least that agricultural goes up acceptable.This carrier can be solid or liquid.
Suitable solid carrier is as follows:
Ammonium salt for example, with natural rock powder such as kaolin, clay, talcum, chalk, quartz, attapulgite, montmorillonite or diatomite and the synthetic rock powder such as silica, aluminium oxide and the silicate of polymolecularity, petroleum paraffin, solid fertilizer, water, alcohols---preferred butanols, organic solvent, mineral oil and vegetable oil, and their derivative;
Suitable granular solids carrier has: for example pulverize and the natural rock of classification, for example calcite, marble, float stone, sepiolite, dolomite and synthetic inorganic and organic dust particle; With the particle of organic material for example paper, wood chip, coconut husk, corn stalk and tobacco rods;
The gaseous diluent of liquefaction or carrier are meant and are the liquid of gaseous state, for example aerosol spray such as halogenated hydrocarbons and butane, propane, nitrogen and carbonic acid gas at normal temperatures and pressures.
The adhesive that can use in preparation has for example carboxymethyl cellulose, natural and synthetic powder, particle or latex shaped polymer, and as gum Arabic, polyvinyl alcohol, polyvinyl acetate and natural phospholipid such as cephalin and lecithin, and synthetic phospholipid.Other additive can be mineral oil or the vegetable oil and the wax class of optional modification.
Suitable filler has, water for example, polarity and nonpolar organic chemistry liquid, wherein organic chemistry liquid is from for example aromatics and non-aromatic hydrocarbons (paraffinic for example, alkyl benzene, Fluhyzon, chlorobenzene), (if suitable, it also can replace for alcohols and polyalcohols, etherificate and/or esterification), ketone (acetone for example, cyclohexanone), ester class (comprising fats and oils) and ether or polyethers, unsubstituted and substituted amine, amide-type, lactams (for example N-alkyl pyrrolidine ketone) and lactone, sulfone class and sulfoxide class (for example dimethyl sulfoxide (DMSO)) classification.
If used filler is a water, also can use-case such as organic solvent make secondary solvent.The suitable liquid solvent mainly contains: aromatic species, for example dimethylbenzene, toluene or Fluhyzon, chlorinated aromatics and chlorination aliphatic hydrocarbon be chlorobenzene, vinyl chloride or carrene for example, aliphatic hydrocarbon is cyclohexane or paraffinic, for example petroleum distillate, mineral oil and vegetable oil for example, alcohols is butanols or ethylene glycol and ethers and ester class for example, ketone is acetone, MEK, methyl iso-butyl ketone (MIBK) or cyclohexanone for example, and intensive polar solvent is dimethyl sulfoxide (DMSO) for example, and water.
The present composition also can contain other component.Particularly, said composition also can contain surfactant.Surfactant can be emulsifier, dispersant or wetting agent or the described surfactant mixtures of ionic or nonionic.That can mention has a for example polyacrylate; lignosulfonates; benzene sulfonate (phenosulphonic acid salt) or naphthalene sulfonate; oxirane and fatty alcohol or with fatty acid or with the condensation polymer of fatty amine; the phenol (particularly alkylphenol or aryl phenol) that replaces; phosphate (sulphosuccinic acidester) salt; taurine derivatives (particularly alkyltaurate); polyoxyethylenated alcohol class or phenol phosphide; the polyalcohols fatty acid ester; and contain sulphate; the derivative of the The compounds of this invention of sulfonate and phosphate official energy, for example alkylaryl polyglycol ether class; alkylsulfonate; alkyl sulfate; arylsulphonate; protein hydrolyzate; lignin sulfite waste liquor and methylcellulose.When reactive compound and/or inert carrier when being water-soluble and, must there be at least a surfactant usually when used carrier agent (vector agent) during for water.The surface-active contents that preferably can contain 5 weight %-40 weight % compositions.
Suitable emulsifier and/or blowing agent have: for example nonionic and ionic emulsifying agent, for example polyoxyethylene fatty acid ester, polyoxyethylene aliphatic alcohol ether class.Suitable dispersant is nonionic and/or ionic species, and it is for example from containing pure POE and/or POP ether, acid and/or POP or POE ester, alkylaryl and/or POP or POE ether, fat and/or POP-POE adduct, POP and/or POE polyol derivative, POE and/or POP/ sorbitan or sugared adduct, alkyl or aryl sulphate, sulfonate and phosphate or corresponding PO ether adduct class.In addition, suitable oligomer or polymer, for example based on vinyl monomer, acrylic acid, independent EO and/or PO or its with for example (gather) combining of alcohols or (gathering) amine.Also can use lignin and sulfonic acid thereof.Cellulose, aromatic series and/or aliphatic sulfonic acid and and the formaldehyde adducts thereof of simple cellulose (simple cellulose) and modification.Suitable dispersant is for example lignin sulfite waste liquor and methylcellulose.
Operable colouring agent for example has inorganic pigment such as iron oxide, titanium oxide, the ferrous orchid of cyanogen (ferrocyan blue), with organic pigment such as alizarin dyes, azo dyes and metal phthalocyanine dyestuff, and trace element is as iron, manganese, boron, copper, cobalt, molybdenum and zinc salt.
Randomly, can comprise that also other adds component, for example protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent, stabilizing agent, chelating agent.More widely, described reactive compound routinely preparation technique combine with any solid or liquid additive.
Usually, composition of the present invention can contain 0.05-99 weight %, preferred 1-70 weight %, the reactive compound of 10-50 weight % most preferably.
Bond of the present invention or composition can its dosage form or type of service prepared therefrom use, aerosol for example, microcapsule formulations, cold mist agent (cold fogging concentrate), thermal fog, fine granule, granula subtilis, the seed dressing suspending agent, ready to use solution, pulvis, missible oil, oil-in-water emulsion, water-in-oil emulsion, big granula, fine granule, the oil-dispersing property pulvis, oil suspending agent, finish, foaming agent (froths), paste, plant clothing agent (seed), colloidal suspending agent (suspending agent), suspended emulsion, aqueous solvent, suspending agent, soluble powder, granule, water-soluble granular formulation or tablet, the seed dressing water solube powder, wetting powder, natural and the synthetic material of dipping reactive compound, in the polymeric material with the seed involucrum in microcapsule formulations, and cold mist of ULV and hot mist preparation, Compressed Gas, foaming agent, stylus, the dry seeds inorganic agent, handle the solution of seed, the liquid of ultra low volume (ULV), the suspension of ultra low volume (ULV), water-dispersible granules or tablet, wet-mixing kind water dispersant.
Described preparation is by---for example conventional filler and solvent or thinner, emulsifier, dispersant and/or adhesive or fixative, wetting agent, waterproofing agent---mixes with a kind of known way being prepared with reactive compound or active agent combinations and conventional additives, if suitable, add drier and UV stabilizing agent, colouring agent, pigment, defoamer, preservative, secondary thickener (secondary thicknener), adhesive, gibberellin and water and other processing aid.
Described composition not only comprises the composition that promptly is applied to plant or seed, and comprises dense commercial composite, and described seed is for example sprayed by suitable equipment or dusting device is handled, and described composition must dilute before being applied to crop.
The control of the phytopathogenic fungi of plant and/or microorganism and/or insect is mainly by carrying out with crop protection agents processing soil and plant shoot position behind the destruction seedling.Owing to consider that crop protection agents is to environment and the healthy issuable influence of human and animal, so make great efforts to reduce the amount of the reactive compound of using.
Active agent combinations of the present invention can its commercial preparation and by the type of service that mixes with other the active compound use of described formulation preparation, and described other reactive compound is insecticide, attractant, bactericidal agent, bactericide, miticide, nematocide, fungicide, growth regulatory substance, weed killer herbicide, safener, fertilizer or semiochemical for example.
With active agent combinations of the present invention the processing of plant and plant parts is directly carried out with conventional treatment method or undertaken by acting on its environment, habitat or storage areas, described conventional treatment method is for example irrigated (perfusion), drip irrigation, sprinkling, vaporization (vaporizing), atomizing (atomizing), broadcasts sowing, dusts, foams, is coated with (spreading-on), is reached as dressing seed with dry seeds inorganic agent, seed dressing solution, seed dressing water-soluble powder, wet-mixing kind water-soluble powder; Or by crust, under the situation of propagating materials, especially under the situation of seed, also can be by dry treatment, wet process, liquid handling, one or more layers dressing.In addition, also can use this reactive compound, or active agent preparations or reactive compound itself are injected soil by the ultra low volume method.
The purposes that processing method of the present invention also provides compound (A) and (B) used with while, independent or continuous mode.
Conventional active compound doses/the rate of application that uses of processing method of the present invention is usually and advantageously
-handle for leaf: 0.1-10,000g/ha, preferred 10-1,000g/ha, more preferably 25-300g/ha; Under perfusion or drip irrigation situation about using, especially when the use inert substance for example rock wool or or during perlite, dosage even also can reduce.
-for seed treatment: every double centner seed 2-200g, preferred every double centner seed 3-150g;
-for soil treatment: 0.1-10,000g/ha, preferred 1-5,000g/ha.
The pointed dosage of this paper only provides with the form of the example of the inventive method.Those skilled in the art will know that how to change application dosage, particularly the kind according to processed plant or crop changes.
In certain section time range, resist insect and/or phytopathogenic fungi and/or microorganism and/or insect for the plant after the protection processing, can use bond of the present invention.The time range span that protective effect comes into force is generally 1-28 days, preferably handled behind the plant 1-14 days with bond or treatment of plant propagation material after be up to 200 days.
Processing method of the present invention also can be used for handling propagating materials for example stem tuber or rhizome, and seed, seedling or sprigging and plant or plant transplanting.This processing method also can be used for handling root.Processing method of the present invention also can be used for handling the plant shoot position, and position, described ground is for example about trunk, stem or stem, leaf, flower and the fruit of plant.
Another aspect of the present invention is that the plant resource of natural life circulation or the method for animal sources natural materials or their form processing are taken from protection; This method comprises compound (A) and (B) bond is applied to described plant resource or zoogenous natural materials or their form processing with the synergistic effect amount.
Embodiment preferred is taken from the natural materials of plant resource of natural life circulation or the method for their form processing for protection, this method comprises compound (A) and (B) bond are applied to the natural materials of described plant resource or their form processing with the synergistic effect amount.
Another preferred embodiment is taken from the fruit of natural life circulation for protection---preferred the operatic circle, drupe, berry and citrus fruit, or the method for their form processing; This method comprises compound (A) and (B) bond is applied to the natural materials of described plant resource or their form processing with the synergistic effect amount.
The present invention includes with compound (A) and compound (B) while methods for the treatment of seed.The present invention also comprises with compound (A) and selected compounds (B) difference methods for the treatment of seed.
The present invention also comprises the seed of having used compound (A) and compound (B) to handle simultaneously.The present invention also comprises the seed of having used compound (A) and compound (B) to handle respectively.For a kind of seed in back, active ingredient can be applied in the different layers.These layers can be chosen wantonly by other layer separation that can comprise or not comprise active ingredient.
Bond of the present invention and/or composition are particularly suitable for handling seed.The major part that causes by insect and/or phytopathogenic fungi and/or microorganism to cultivated species destroy by seed that infects lay up period and sowing go into during seed after underground and the plant germination and germinate after seed take place.Since just the root of growing plant and bud is responsive especially and even a spot of destruction all can cause the withered of whole strain plant, therefore should the stage especially crucial.Therefore people are to by using suitable medicament protection seed and germination plant to have sizable interest.
By handle plant seed pest control and/or phytopathogenic fungi and/or microorganism for people long-term known to and be the theme of updating.But, in the processing of seed, have many problems, and can not always solve satisfactorily.Therefore, be worth the method for exploitation protection seed and germination plant, this method makes needn't be after planting or use plant protection product behind the plant germination in addition.Also be worth optimizing the amount of institute's applying active substances, the destruction that does not make plant originally experience the reactive compound of using so that protect the invasion and attack of seed and germination plant opposing insect and/or phytopathogenic fungi and/or microorganism as far as possible best.Particularly, for the minimal consumption with plant protection product reaches the best protection of seed and germination plant, methods for the treatment of seed also should be considered sterilization and/or the insecticidal properties that genetically modified plants are intrinsic.
Therefore the invention particularly relates to the method that protection seed and germination plant avoid the invasion and attack of insect and/or phytopathogenic fungi and/or microorganism, wherein said seed is with bond of the present invention/compositions-treated mistake.The invention still further relates to bond/composition of the present invention in addition and be used to handle seed avoids insect and/or phytopathogenic fungi and/or microorganism with protection seed and germination plant purposes.And the present invention relates to protecting it to avoid the seed that insect and/or phytopathogenic fungi and/or microorganism use bond/compositions-treated of the present invention to cross.
An advantage of the invention is because the distinctive internal absorption characteristic of bond/composition of the present invention; handle with this bond/composition and not only to protect seed itself to avoid insect and/or phytopathogenic fungi and/or microorganism encroach, and the plant of being unearthed after the protection rudiment.Can save at seeding time or thereafter in this way and soon cultivated species directly be handled.
Another advantage is for comparing with single reactive compound respectively, the antifungal of bond/composition of the present invention and/or kill the collaborative increase of insect active, this activity surpass single two reactive compounds using activity add and.Can optimize the amount of the reactive compound of using in this way.
What also can be looked at as advantage is, mixture of the present invention also can be used for particularly transgenic seed, thereby can express protein at insect and phytopathogenic fungi and/or microorganism by the plant of this seed germination.By using the described seed of chemicals treatment of the present invention; some insect and/or phytopathogenic fungi and/or microorganism can be prevented and treated by for example expressing insecticidal proteins; and surprisingly in addition be to use medicament of the present invention; synergistic activity increases, and this synergistic activity has further improved the protective effect validity that avoids the insect invasion and attack.
Medicament of the present invention is suitable for protecting the seed of all types plant variety, described type be used in agricultural, the greenhouse, in the forestry, bar excute a law in, all kinds described in the gardening or the vineyard.Particularly, this relates to the seed of cereal (for example wheat, barley, rye, triticale, grain, oat, rice), corn, cotton, soybean, potato, sunflower, Kidney bean, coffee, beet (for example sugar beet, beet and fodder beet), peanut, rape, rape seed, opium poppy, olive, coconut, cocoa, sugarcane or tobacco.Bond/composition of the present invention also is suitable for handling seed (for example tomato, cucumber, onion and lettuce), lawn, meadow and the ornamental plants of foregoing fruit plant and vegetables.Particularly importantly to the processing of wheat, barley, rye, triticale, oat, corn, rice, soybean, cotton, rape, the blue seed that rues.
As previously mentioned, with the processing particular importance of bond/composition of the present invention to transgenic seed.This relates to the plant seed that contains at least a heterologous gene usually, and described heterologous gene control has the polypeptide expression of specific insecticidal properties.The heterologous gene of transgenic seed can derive from microorganism for example bacillus, rhizobium (Rhizobium), pseudomonad (Pseudomonas), Serratia (Serratia), trichoderma (Trichoderma), Clavibacter, glomus (Glomus) or Gliocladium (Gliocladium).The present invention is particularly suitable for handling the transgenic seed that contains at least a heterologous gene, and described heterologous gene derives from Bacillus, and described gene outcome has been showed the activity to European corn borer and/or corn root leaf A (western corn rootworm).Particularly preferably be the heterologous gene that derives from bacillus thuringiensis,Bt.
In the context of the present invention, bond/composition of the present invention is applied to seed with itself or suitable formulation.Preferably under stable the state that is without prejudice during being enough to seed is being handled, handle seed.To the processing of seed usually gather and sow between any time carry out.The conventional seed that uses is for separating and removed the seed of spadix, shell, stem, pod, fine hair or pulp from plant.That use is gathered, purify and be dried to the seed that moisture is lower than 15% w/w.Perhaps also can use the seed of dry back with water treatment and then drying.
Usually must be noted that during seed treatment that the amount that is applied to the bond/composition of the present invention of seed and/or other additive is selected in the mode that can not damage the germination of seed and can not destroy the plant that emerges.Especially note when using, can showing the reactive compound of phytotoxic effect with certain amount.
Bond/composition of the present invention can not contain other component and not diluted and directly use.Usually preferably bond/composition of the present invention is applied to seed with the form of dosage forms.The dosage forms of seed treatment and method are known and for example be described in the following document for those skilled in the art: US 4,272,417 A, US 4,245,432 A, US4,808,430 A, US 5,876,739 A, US 2003/0176428 A1, WO 2002/080675A1, WO 2002/028186 A2.
Spendable active agent combinations of the present invention and composition can change into conventional seed pelleting formulation example such as solution, emulsion, suspending agent, pulvis, foaming agent, slurries or other seed coating material and ULV preparation.
Described preparation prepares by in a known way reactive compound or active agent combinations being mixed with conventional additives, for example conventional filler of described conventional additives and solvent or thinner, colouring agent, wetting agent, dispersant, emulsifier, defoamer, preservative, secondary thickener, adhesive, gibberellin and optional water.
The suitable colouring agent that can be present in the coating agent for seed of the present invention comprises that all routines are used for this purpose colouring agent.Both the pigment that is slightly soluble in water can be used, also water-soluble dyestuff can be used.The example that can mention comprises that known name is called the colouring agent of rhodamine B, C.I. pigment red 122 and C.I. solvent red 1.
Can be present in suitable wetting agent in the seed pelleting preparation of the present invention comprises and promotes wetting and be usually used in the used material of active agrochemicals.Can preferably use Fluhyzon-sulfonate, for example diisopropyl or diisobutyl naphthalene-sulfonate.
The suitable dispersant and/or the emulsifier that can be present in the seed pelleting preparation of the present invention comprise all non-ionic, anionic and cationic dispersants commonly used in the active agrochemicals of summarizing above.
The suitable defoamer that can be present in the seed pelleting preparation of the present invention is included in all foam inhibitory substances commonly used in the active agrochemicals.Can preferably use silicone antifoam agent and dolomol.
The suitable preservatives that can be present in the seed pelleting preparation of the present invention comprises all substances that can use for this purpose in agrochemical composition.In the mode of example, that can mention has dichlorophen and a phenmethylol hemiformal.
The suitable secondary thickener that can be present in the seed pelleting preparation of the present invention comprises all substances that can use for this purpose in agrochemical composition.Preferred suitable clay that cellulose derivatives, acrylic acid derivative, xanthans, modification are arranged and polymolecularity silica.
The suitable bonding that can be present in the seed pelleting preparation of the present invention is included in spendable all conventional adhesives in the seed pelleting.That preferably mentions has polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and a tylose.
The suitable gibberellin that can be present in the seed pelleting preparation of the present invention comprises preferred gibberellin A1, A3 (=gibberellic acid), A4 and A7, preferred especially gibberellin A 3 (=gibberellic acid).The gibberellin of formula (II) is known, the nomenclature of gibberellin can find in the following document of mentioning (referring to Wegler " Chemie der Pflanzenschutz-andSch_dlingsbek_mpfungsmittel ", the 2nd volume, Springer Verlag, Berlin-Heidelberg-New York, 1970, the 401-412 pages or leaves).
The present invention comprises all mixing apparatus that can conventional be used for dressing with the seed pelleting preparation or by the suitable mixing apparatus that adds water preparation processing prepared therefrom seed.The concrete grammar that adopts during dressing comprises to be introduced seed blender, is evenly distributed on the seed adding its concrete requirement and mix until preparation after coating agent for seed itself or the water in advance dilution.Randomly, then carry out drying process.
Active agent combinations with good plant compatibility and favourable homeothermal animal toxicity is suitable for preventing and treating noxious animal, particularly in agricultural, in the forest, in the protection of storing product and material and the insects, spider shape guiding principle animal and the nematoda that in hygiene department, run into.It preferably is used for blade face and soil treatment with the crop production compositions form.
Active agent combinations of the present invention is to conventional sensitivity and the resistance species and all effective to all or single developmental stage of insect.Above-mentioned insect comprises:
Isopoda (Isopoda), for example, comb beach louse (Oniscus asellus), pillworm (Armadillidium vulgare), ball pillworm (Porcellio scaber).Doubly sufficient order (Diplopoda), for example, Blaniulus guttulatus.Lip foot order (Chilopoda), for example, DIWUGONG belongs to (Geophilus carpophagus), Scutigera spp..Comprehensive order (Symphyla), for example, kahikatea worm (Scutigerella immaculata).Thysanoptera (Thysanura), for example, silverfish (Lepisma saccharina).Collembola (Collembola), for example, arms Onychiurus arcticus (Onychiurus armatus).Orthoptera (Orthoptera), for example, tame Xi (Acheta domesticus), Gryllotalpa spp (Gryllotalpa spp.), migratory locusts belong to (Locusta migratoriamigratorioides), black locust belongs to (Melanoplus spp.), desert locust (Schistocercagregaria).Blattaria (Blattaria), for example oriental cockroach (Blatta orientalis), American cockroach (Periplaneta americana), leucophaea maderae (Leucophaeamaderae), blatta germanica (Blattela germanica).Dermaptera (Dermaptera), for example, European earwig (Forficula auricularia).Isoptera (Isoptera), for example, Reticulitermes (Reticulitermes spp.).Anoplura (Phthiraptera), for example pediculus humanus corporis (Pediculus humanus corporis), Haematopinus (Haematopinus spp.), Linognathus (Linognathus spp.), Trichodectes (Trichodectes spp.), Damalinia (Damalinia spp.).Thrips (Thysanoptera), for example, greenhouse bar hedge thrips (Hercinothrips femoralis), onion thrips (Thrips tabaci), palm thrips (Thrips palmi), Frankliniella occidentalis (Frankliniella occidentalis).Heteroptera (Heteroptera), for example, Eurygasterspp belongs to (Eurygaster spp.), Dysdercusintermedius, square butt stinkbug (Piesma quadrata), bed bug (Cimexlectularius), phodnius prolixus (Rhodnius prolixus), Triatoma (Triatomaspp.).Homoptera (Homoptera), for example, aleyrodid (Aleurodes brassicae), Bemisia tabaci (Bemisia tabaci), greenhouse whitefly (Trialeurodes vaporariorum), cotten aphid (Aphis gossypii), cabbage aphid (Brevicoryne brassicae), the tea Fischer conceals knurl aphid (Cryptomyzus ribis), black bean aphid (Aphis fabae), apple aphid (Aphispomi), wooly aphis (Eriosoma lanigerum), mealy plum aphid (Hyalopterusarundinis), grape phylloxera (Phylloxera vastatrix), Pemphigus spp., English grain aphid belongs to (Macrosiphum avenae), tumor aphid genus (Myzus spp.), phorodon aphid (Phorodon humuli), rhopalosiphum padi (Rhopalosiphum padi), Empoasca flavescens (Empoasca spp.), Euscelis bilobatus, rice leafhopper (Nephotettixcincticeps), Lecanium corni, olive helmet a red-spotted lizard (Saissetia oleae), small brown rice planthopper (Laodelphax striatellus), brown planthopper (Nilaparvata lugens), California red scale (Aonidiella aurantii), ivy Aspidiotus (Aspidiotus hederae), mealybug belongs to (Pseudococcus spp.), Psylla spp (Psylla spp.).Lepidoptera, for example, Pectinophora gossypiella (Pectinophora gossypiella), loose looper (Bupaluspiniarius), winter geometrid moth (Cheimatobia brumata), the thin moth of apple (Lithocolletisblancardella), apple ermine moth (Hyponomeuta padella), diamond-back moth (Plutellaxylostella), malacosoma neustria (Malacosoma neustria), pornography and drug moth (Euproctis chrysorrhoea), Euproctis (Lymantria spp.), cotton lyonetid (Bucculatrix thurberiella), tangerine lyonetid (Phyllocnistis citrella), Agrotis (Agrotis spp.), root eating insect belongs to (Euxoa spp.), the dirty Noctua (Feltiaspp.) of cutting, earias insulana (Earias insulana), Heliothis (Heliothis spp.), tomato moth (Mamestra brassicae), small noctuid (Panolis flammea), Spodoptera (Spodoptera spp.), cabbage looper (Trichoplusia ni), codling moth (Carpocapsa pomonella), Pieris spp (Pieris spp.), straw borer spp (Chilo spp.), corn borer (Pyrausta nubilalis), Anagasta kuehniella (Ephestia kuehniella), greater wax moth (Galleria mellonella), curtain rain moth (Tineola bisselliella), bag rain moth (Tinea pellionella), brownly knit moth (Hofmannophila pseudospretella), the yellow volume of flax moth (Cacoecia podana), Capua reticulana, spruce bunworm (Choristoneura fumiferana), grape codling moth (Clysia ambiguella) (Clysia ambiguella), tea long paper moth (Homona magnanima), the green volume of oak moth (Tortrix viridana), Cnaphalocerus spp., Oulema oryzae (Oulemaoryzae).Coleoptera (Coleoptera), for example, furniture death watch beetle (Anobium punctatum), lesser grain borer (Rhizopertha dominica), dislike bar bean weevil (Bruchidius obtectus), acanthoscelides obtectus (Acanthoscelides obtectus), North America house longhorn beetle (Hylotrupesbajulus), willow firefly chrysomelid (Agelasticaalni), colorado potato beetle (Leptinotarsadecemlineata), horseradish ape chrysomelid (Phaedon cochleariae), chrysomelid genus (Diabrotica spp.), rape golden head flea beetle (Psylliodes chrysocephala), mexican bean ladybird (Epilachna varivstis), Atomaria spp., saw-toothed grain beetle (Oryzaephilus surinamensis), flower resembles genus (Anthonomus spp.), grain weevil belongs to (Sitophilus spp.), black grape ear image (Otiorrhynchus sulcatus), the banana rhizome resembles (Cosmopolites sordidus), wild cabbage pod weevil (Ceuthorrhynchusassimilis), alfalfa leaf resembles (Hypera postica), khapra beetle belongs to (Dermestes spp.), the spot khapra beetle belongs to (Trogoderma spp.), Anthrenus (Anthrenus spp.), moth-eaten belong to (the Attagenus spp.) of fur, moth-eaten belong to (the Lyctus spp.) of powder, pollen beetle (Meligethes aeneus), Ptinus (Ptinus spp.), golden spider beetle (Niptushololeucus), globose spider beetle (Gibbium psylloides), Tribolium (Triboliumspp.), yellow mealworm (Tenebrio molitor), click beetle belongs to (Agriotes spp.), wide chest Agriotes spp (Conoderus spp.), the west melolonthid in May (Melolonthamelolontha), the potato melolonthid (Amphimallon solstitialis), the brown New Zealand rib wing melolonthid (Costelytra zealandica), rice root weevil (Lissorhoptrusoryzophilus).Hymenoptera (Hymenoptera), for example, pine sawfoy belongs to (Diprionspp.), real tenthredinidae (Hoplocampa spp.), the hair ant belongs to (Lasius spp.), MonomoriumMayr (Monomorium pharaonis), Vespa (Vespa spp.).Diptera (Diptera), for example, Aedes (Aedes spp.), Anopheles (Anopheles spp.), Culex (Culexspp.), Drosophila melanogaster (Drosophila melanogaster), Musca (Musca spp.), Fannia (Fannia spp.), calliphora erythrocephala (Calliphora erythrocephala), Lucilia (Lucilia spp.), Carysomyia (Chrysomyia spp.), Cuterebra (Cuterebraspp.), Gasterophilus (Gastrophilus spp.), Hyppobosca spp., Genus Stomoxys (Stomoxys spp.), Oestrus (Oestrus spp.), Hypoderma (Hypoderma spp.), Gadfly (Tabanus spp.), Tannia spp., garden march fly (Bibio hortulanus), Oscinella frit (Oscinella frit), grass Hylemyia (Phorbia spp.), lamb's-quarters spring fly (Pegomyia hyoscyami), Mediterranean Ceratitis spp (Ceratitis capitata), the big trypetid of olive (Dacus oleae), Europe daddy-longlegs (Tipula paludosa), Hylemyia (Hylemyia spp.), liriomyza bryoniae belongs to (Liriomyza spp.).Siphonaptera (Siphonaptera), for example, Xanthopsyllacheopis (Xenopsylla cheopis), Ceratophyllus (Ceratophyllusspp.).Arachnids (Arachnida), for example, Middle East gold scorpion (Scorpio maurus), latrodectus mactans (Latrodectus mactans), Acarus siro (Acarus siro), Argasspp., Ornithodoros (Ornithodoros spp.), Dermanyssus gallinae (Dermanyssusgallinae), Eriophyes ribis, the tangerine rust mite (Phyllocoptruta oleivora) that rues, Boophilus (Boophilus spp.), Rh (Rhipicephalus spp.), Amblyomma (Amblyomma spp.), Hyalomma (Hyalomma spp.), hard tick belongs to (Ixodesspp.), Psoroptes (Psoroptes spp.), Chorioptes (Chorioptes spp.), itch mite belongs to (Sarcoptes spp.), tarsonemid belongs to (Tarsonemus spp.), Bryobia praetiosa (Bryobia praetiosa), Panonychus citri belongs to (Panonychus spp.), Tetranychus (Tetranychus spp.), half tarsonemid belongs to (Hemitarsonemus spp.), short whisker Acarapis (Brevipalpus spp.).
The plant nematode class comprises, for example, Pratylenchidae belongs to (Pratylenchus spp.), similar similes thorne (Radopholus similis), fuller's teasel stem eelworm (Ditylenchusdipsaci), the nematode (Tylenchulus semipenetrans) of partly puncturing, Heterodera (Heterodera spp.), ball Heterodera (Globodera spp.), Meloidogyne (Meloidogyne spp.), Aphelenchoides (Aphelenchoides spp.), minute hand Turbatrix (Longidorus spp.), Xiphinema (Xiphinema spp.), burr Turbatrix (Trichodorus spp.), umbrella Aphelenchoides (Bursaphelenchus spp.).
In can plant or crop pest by the inventive method control, that can mention has:
The powdery mildew disease, for example
Bu Shi Erysiphe (Blumeria) disease that causes by grass family Bu Shi powdery mildew (Blumeria graminis) for example,
Podosphaera (Podosphaera) disease that causes by white cross hair list softgel shell (Podosphaera leucotricha) for example,
For example the single softgel shell that is caused by garden balsam list softgel shell (Sphaerotheca fuliginea) belongs to (Sphaerotheca) disease,
Uncinula (Uncinula) disease that causes by grape snag shell (Uncinula necator) for example.
The rust disease for example
Glue Rust (Gymnosporangium) disease that causes by Gymnosporangium sabinae for example,
For example the hunchbacked spore rust that is caused by coffee camel spore rest fungus (Hemileia vastatrix) belongs to (Hemileia) disease,
Layer rest fungus (Phakopsora) disease that causes by yam bean layer rest fungus (Phakopsora pachyrhizi) and mountain horseleech layer bacterium (Phakopsora meibomiae) for example,
Handle rest fungus (Puccinia) disease that causes by Puccinia recondita (Puccinia recondite) and wheat leaf rust (Puccinia triticina) for example,
Uromyces (Uromyces) disease that causes by wart top uromyce (Uromyces appendiculatus) for example,
Oomycetes disease disease for example
For example coil dish downy mildew (Bremia) disease that downy mildew (Bremia lactucae) causes by lettuce,
Downy mildew (Peronospora) disease that causes by pea downy mildew (Peronospora pisi) and Cruciferae downy mildew (Peronospora brassicae) for example,
Epidemic disease mould (Phytophthora) disease that causes by phytophthora infestans (Phytophthora infestans) for example,
For example give birth to axle downy mildew (Plasmopara) disease that axle downy mildew (Plasmopara viticola) causes by grape,
False downy mildew (Pseudoperonospora) disease that causes by the false downy mildew of the false downy mildew of grass (Pseudoperonospora humuli) and Cuba (Pseudoperonospora cubensis) for example,
Rotten mould (Pythium) disease that causes by ultimate corruption mould (Pythium ultimum) for example,
Leaf spot, leaf spot blight and leaf blight disease for example,
Alternaria (Alternaria) disease that causes by early blight chain lattice spore (Alternaria solani) for example,
For example You Chard dish is given birth to Cercospora (Cercospora) disease that tail spore (Cercospora beticola) causes,
The Cladiosporium disease that causes by Cladiosporium cucumerinum for example,
For example the cochliobolus that is caused by standing grain cochliobolus (Cochliobolus sativus) belongs to (Cochliobolus) disease,
(conidial form: moral this mould (Drechslera), Syn: the long spore mould (Helminthosporium) of wriggling);
Colletotrichum (Colletotrichum) disease that causes by bean anthrax bacteria (Colletotrichum lindemuthianum) for example,
The Cycloconium disease that causes by Cycloconium oleaginum for example,
For example by seat shell (Diaporthe citri) between citrus cause between the seat shell belong to (Diaporthe) disease,
Elsinoe (Elsinoe) disease that causes by citrus Elsinochrome (Elsinoe fawcettii) for example,
For example the long spore of dish that is caused by the happy long spore of colour disk (Gloeosporium laeticolor) belongs to (Gloeosporium) disease,
For example belong to (Glomerella) disease by enclosing the small cluster shell that small cluster shell (Glomerella cingulata) causes,
Ball seat Pseudomonas (Guignardia) disease that causes by grape Guignardia (Guignardia bidwelli) for example,
Leptosphaeria (Leptosphaeria) disease that causes by Pyricularia oryzae (Leptosphaeria maculans) for example,
The Magnaporthe disease that causes by Magnaporthe grisea for example,
Mycosphaerella (Mycosphaerella) disease that causes by standing grain green-ball chamber bacterium (Mycosphaerelle graminicola) and Fijian ball chamber bacterium (Mycosphaerelle fijiensis) for example,
The Phaeosphaeria disease that causes by Phaeosphaeria nodorum for example,
For example by nuclear cavity Pseudomonas (Pyrenophora) disease that causes of circle nuclear cavity bacteria (Pyrenophora teres),
The Ramularia that causes by Ramularia collo-cygni (Ramularia) disease for example,
Rhynchosporium spp (Rhynchosporium) disease that causes by rye beak spore (Rhynchosporium secalis) for example,
For example the pin spore that is caused by Septoria apii (Septoria apii) belongs to (Septoria) disease,
For example examine nuclear coral Pseudomonas (Typhula) disease that coral bacterium (Thyphula incarnata) causes by the meat spore,
Venturia (Venturia) disease that causes by apple black star bacteria (Venturia inaequalis) for example.
Root and stem disease evil are for example
The corticium that causes by Corticium graminearum (Corticium) disease for example,
The Fusarium disease that causes by sharp sickle spore (Fusarium oxysporum) for example,
Softgel shell bacterium (Gaeumannomyces) disease that causes by take-all (Gaeumannomyces graminis) for example,
Rhizoctonia (Rhizoctonia) disease that causes by Rhizoctonia solani Kuhn (Rhizoctonia solani) for example,
Oculimacula (Tapesia) disease that causes by Oculimacula Tapesia acuformis for example,
Thiclaviopsis (Thielaviopsis) disease that causes by thielaviopsis sp (Thielaviopsis basicola) for example.
Spadix and panicled spike (comprising corncob) disease for example
The Alternaria disease that causes by Alternaria kind (Alternaria spp.) for example,
Aspergillus (Aspergillus) disease that causes by aspergillus flavus (Aspergillus flavus) for example,
Cladosporium (Cladosporium) disease that causes by dendritic branch spore (Cladiosporium cladosporioides) for example,
Claviceps (Claviceps) disease that causes by ergot (Claviceps purpurea) for example,
The Fusarium disease that causes by yellow sickle spore (Fusarium culmorum) for example,
Gibberella (Gibberella) disease that causes by Gibberella zeae (Gibberella zeae) for example,
For example belong to the Monographella disease that (Monographella nivalis) causes by the rotten bright shuttle spore of snow.
Smut and bunt disease are for example
Axle Ustilago (Sphacelotheca) disease that causes by axle Ustilago (Sphacelotheca reiliana) for example,
Tilletia (Tilletia) disease that causes by wheat net fungus tilletia (Tilletia caries) for example,
Urocystis (Urocystis) disease that causes by latent bar smut (Urocystis occulta) for example,
Smut (Ustilago) disease that causes by naked smut (Ustilago nuda) for example.
Fruit rot and mouldy disease are for example
The aspergillus disease that causes by aspergillus flavus for example,
Botrytis (Botrytis) disease that causes by Botrytis cinerea (Botrytis cinerea) for example,
Penicillium (Penicillium) disease that causes by penicillium expansum (Penicillium expansum) and penicillium purpurogenum (Penicillium purpurogenum) for example,
Sclerotinia (Sclerotinia) disease that causes by sclerotinite (Sclerotinia sclerotiorum) for example,
For example the Verticillium dahliae that is caused by black and white Verticillium dahliae (Verticillium alboatrum) belongs to (Verticillium) disease,
Rotten, the mouldy and disease of dampinging off that passes with soil that kind passes,
For example give birth to the Alternaria disease that chain lattice spores (Alternaria brassicicola) cause by rape,
Aphanomyces (Aphanomyces) disease that causes by root-rot silk capsule mould (Aphanomyces euteiches) for example,
The Ascochyta that causes by Ascochyta lentis (Ascochyta) disease for example,
The aspergillus disease that causes by aspergillus flavus for example,
The Cladosporium disease that causes by draft branch spore (Cladosporium herbarum) for example,
For example the cochliobolus that is caused by the standing grain cochliobolus belongs to disease,
(conidium: this is mould for moral, bipolaris (Bipolaris) Syn: the long spore of wriggling is mould);
The colletotrichum disease that causes by pepper anthracnose bacterium (Colletotrichum coccodes) for example,
The Fusarium disease that causes by yellow sickle spore for example,
The Gibberella disease that causes by Gibberella zeae for example,
The Macrophomina disease that causes by charcoal rot for example,
For example belong to the Monographella disease that causes by the rotten bright shuttle spore of snow,
The Penicillium disease that causes by penicillium expansum for example,
Phoma disease (Phoma) disease that causes by root timber rot (Phoma lingam) for example,
Phomopsis (Phomopsis) disease that causes by soybean pod stalk withered rotten disease (Phomopsis sojae) for example,
For example the phytophthora root rot that is caused by Phytophthora cactorum (Phytophthora cactorum) does harm to,
The nuclear cavity Pseudomonas disease that causes by wheat class nuclear cavity bacteria (Pyrenophora graminea) for example,
The Pyricularia disease that causes by piricularia oryzae (Pyricularia oryzae) for example,
For example by the mould rotten mould disease that causes of ultimate corruption,
For example by the microbial Rhizoctonia disease of miliary damping-off,
Rhizopus (Rhizopus) disease that causes by Rhizopus oryzae (Rhizopus oryzae) for example,
For example the bulbil that is caused by Sclerotium rolfsii (Sclerotium rolfsii) belongs to (Sclerotium) disease,
Septoria (Septoria) disease that causes by septoria musiva bacterium (Septoria nodorum) for example,
For example examine nuclear coral Pseudomonas (Typhula) disease that coral bacterium (Typhula incarnata) causes by the meat spore,
Verticillium Nees (Verticillium) disease that causes by big beautiful Verticillium dahliae (Verticillium dahliae) for example.
Plant ulcer, witches' broom (Broom) and for example die ack the disease disease
For example do Nectria (Nectria) disease that the red shell bacterium of cancer clump (Nectria galligena) causes by a kind of fruit, such as apple, pear, etc.
The leaf blight disease for example
For example the chain sclerotinia sclerotiorum that is caused by drupe chain sclerotinia sclerotiorum (Monilinia laxa) belongs to (Monilinia) disease.
Leaf blotch exanthema or leaf-curl disease (comprising the flower and the deformity of fruit) for example,
Exoascus (Taphrina) disease that causes by peach external capsule bacterium (Taphrina deformans) for example.
The decline disease of woody plant (wooden plant) for example
The Esca disease that causes by Phaemoniella clamydospora and Phaeoacremoniumaleophilum and Fomitiporia mediterranea for example.
The disease of flower and seed for example
The Botrytis disease that causes by Botrytis cinerea for example.
The stem tuber disease for example
For example by the microbial Rhizoctonia disease of miliary damping-off,
The length that causes by the long spore (Helminthosporium solani) of wriggling of the eggplant mould disease of spore of wriggling for example.
The disease that is caused by the bacterium organism for example
Xanthomonas (Xanthomanas) the bacterial classification disease that bacterial blight of rice (Xanthomonas campestris pv.Oryzae) causes,
The pseudomonas syringae pseudomonad bacterial classification disease that pathogenic mutation (Pseudomonas syringaepv.Lachrymans) causes of shedding tears,
Erwinia (Erwinia) the bacterial classification disease that fire blight of pear (Erwinia amylovora) causes.
The fungal disease of leaf, stem top, pod and seed for example
Wheel line leaf spot (Alternaria leaf spot) (Alternaria spec.atranstenuissima), anthracnose (Anthracnose) (Colletotrichumgloeosporoides dematium var.truncatum), brown spot (Brown spot) (the brown line septoria musiva of soybean (Septoria glycines)), peach leaf shothole disease and leaf blight (Cercospora leaf spot and blight) (Kikuchi tail spore (Cercosporakikuchii)), Choanephora leaf blight (Choanephorainfundibulifera trispora (syn.)), Dactuliophora leafspot (Dactuliophora glycines), downy mildew (Downy Mildew) (northeast downy mildew (Peronospora manshurica)), Drechslera blight (Drechsleraglycini), frogeye leaf spot (Frogeye Leaf spot) (soybean tail spore (Cercosporasojina)), Kidney bean leaf spot (Leptosphaerulina Leaf Spot) (Leptosphaerulina trifolii), phyllosticta leaf spot (Phyllostica LeafSpot) (soybean gives birth to phyllosticta (Phyllosticta sojaecola)), pod and stem fusarium wilt (Pod and Stem blight) (soybean pod stalk withered rotten disease), powdery mildew (Microsphaeradiffusa), Pyrenochaeta Leaf Spot (Pyrenochaeta glycines), Rhizoctonia Aerial, Foliage and Web blight (Rhizoctonia solani Kuhn), rust (yam bean layer rest fungus, mountain horseleech layer bacterium), scab (Scab) (soybean scab circle spore (Sphacelomaglycines)), Stemphylium Leaf blight (handle of crawling mould (Stemphyliumbotryosum)), target (Target Spot) (Corynespora cassicola (Corynespora cassiicola)).
The fungal disease of root and the lower portion of the stem for example
Black root rot (Black Root Rot) (Calonectria crotalariae), charcoal rot (Charcoal Rot) (Macrophomina phaseolina), fusarium wilt (Fusariumblight) or wilt disease (Wilt), root-rot and pod and collar (the sharp sickle spore (Fusariumoxysporum) that rots, straight beak sickle spore (Fusarium or thoceras), half-naked sickle spore (Fusariumsemitectum), scouring rush's sickle spore (Fusarium equiseti)), MycoleptodiscusRoot Rot (Mycoleptodiscus terrestris), Neocosmospora (Neocosmopspora vasinfecta), pod and stem fusarium wilt (seat shell (Diaporthe phaseolorum) between Kidney bean), stem canker disease (StemCanker) (Diaporthe phaseolorum var.caulivora), mould rotten sick (Phytophthora Rot) (big male epidemic disease mould (the Phytophthora megasperma)) of epidemic disease, brown neck rot (Brown Stem Rot) (Phialophora gregata), rotten mould rotten sick (Pythium Rot) (melon and fruit corruption mould (Pythium aphanidermatum), abnormal female corruption mould (Pythium irregulare), pythium debaryanum (Pythium debaryanum), group's knot rotten mould (Pythium myriotylum), ultimate corruption mould (Pythium ultimum)), the rhizoctonia root rot, stem rot (Stem Decay), and damping off (Rhizoctonia solani Kuhn), sclerotinite stem rot (Sclerotinia Stem Decay) (sclerotinite), Sclerotinia SouthernBlight (Sclerotinia rolfsii), intend black root rot (Thielaviopsis RootRot) (thielaviopsis sp (Thielaviopsis basicola)).
The food that other bond of the present invention and composition can also be used to reduce in the plant and the vegetable material of gathering is interior and therefore reduce and the content of the mycotoxin (mycotoxin) in the animal feed.
Especially but not exclusively can given following mycotoxin:
Deoxynivalenol (Deoxynivalenole) (DON), nivalenol (Nivalenole), 15-Ac-DON, 3-Ac-DON, T2 toxin and HT2 toxin, the plain toxin (Fumonisines) of rotten horse, zearalenone (Zearalenone), moniliformin (Moniliformine), fusarine (Fusarine), anguidin (Diaceotoxyscirpenol) (DAS), beauvericin (Beauvericine), enniatin (Enniatine), Fusaroproliferine, Fusarenole, ochratoxin (Ochratoxines), patulin (Patuline), ergot alkaloid (Ergotalkaloides) and aflatoxin (Aflatoxines), they are caused by for example following fungal disease: Fusarium belongs to be planted, fusarium acuminatum (Fusariumacuminatum) for example, fusarium avenaceum (F.avenaceum), F.crookwellense, fusarium culmorum (F.culmorum), Fusarium graminearum (F.graminearum) (Gibberella zeae), art thief sickle-like bacteria (F.equiseti), F.fujikoroi, banana sickle-like bacteria (F.musarum), Fusarium oxysporum (F.oxysporum), proliferation sickle-like bacteria (F.proliferatum), Fusarlum poae (F.poae), F.pseudograminearum, fusarium sambucinum (F.sambucinum), Fusarlum scripi (F.scirpi), fusarium semitectum (F.semitectum), Fusarinm solani (F.solani), Fusarium sporotrichioides (F.sporotrichoides), F.langsethiae, glue fusarium oxysporum (F.subglutinans), fusarium tricinctum (F.tricinctum), fusarium moniliforme (F.verticillioides) and other, and can belong to kind by aspergillus, Penicillium belongs to plants, rye ergot (Claviceps purpurea), Stachybotrys atra (Stachybotrys) genus is planted and other causes.
Fabulous sterilization and/or the insecticidal effect of having showed bond of the present invention or composition in following examples.Though single reactive compound only shows weak sterilization or desinsection drug effect, the drug effect that bond of the present invention or compositions table reveal greater than each compound drug effect simply add and.
If the sterilization of bond of the present invention or composition or desinsection drug effect are greater than the expection drug effect of the bond of two kinds of reactive compounds, the synergistic effect that then always has bactericide or insecticide, the expection drug effect of the bond of described two kinds of reactive compounds can be according to S.R.Colby (" Calculation of the synergistic and antagonistic responsesof herbicide combinations ", Weeds (1967), 15, the 20-22 pages or leaves) calculate by as follows:
If
X is the actual measurement drug effect of the compound (A) of given dose (m g/ha or m ppm),
Y is the actual measurement drug effect of the compound (B) of given dose (n g/ha or n ppm),
E is the compound (A) and compound (B) the actual measurement drug effect together of the given dose of m and n g/ha or m and n ppm,
The Colby formula can as followsly define:
Drug effect is in %.0% drug effect is equivalent to the control group handling, infected fully, and 100% drug effect is represented not observe to infect at all.
Under the sterilization or the situation of insecticidal effect greater than the drug effect of calculating with the Colby formula that actual observation is arrived, bond of the present invention or composition have superadditivity, promptly observe synergistic effect.
Term " synergistic effect " also refers to use " Isoboles; a graphic representationof synergism in pesticides ", Netherlands Journal of PlantPathology, 70 (1964), the defined effect of Tammes method in the 73-80 page or leaf.
The present invention describes by the following example.The present invention is not only limited to described embodiment.
If the sterilization drug effect of bond of the present invention or composition is greater than the expection drug effect of the bond of two kinds of reactive compounds, the synergistic effect that then has bactericide really, the expection drug effect of the bond of described two kinds of reactive compounds can be according to S.R.Colby (" Calculation of thesynergistic and antagonistic responses of herbicidecombinations ", Weeds
15, 20-22) calculate by as follows:
If
X is the drug effect when using reactive compound A with the reactive compound rate of application of m g/ha or m ppm,
Y is the drug effect when using reactive compound B with the reactive compound rate of application of n g/ha or n ppm,
E is the expection drug effect when using reactive compound A and B with the reactive compound rate of application of m and n g/ha or m and n ppm,
Then
The drug effect degree is in %.0% means the drug effect that is equivalent to control group, and 100% drug effect means and do not observe disease.
Under the situation of sterilization drug effect greater than the expection drug effect of calculating with the Colby formula that actual observation is arrived, bond of the present invention or composition have superadditivity, promptly can be observed synergistic effect.
The present invention describes by the following example.
Embodiment A
The black peach aphid test
Solvent: 7 weight portion dimethyl formamides
Emulsifier: 2 weight portion alkylaryl polyglycol ethers
For preparing suitable active agent preparations,, and dope is diluted to desired concn with the water that contains emulsifier with the reactive compound of 1 weight portion and the solvent and the emulsifier of described amount.
Wild cabbage (brassicaoleracea) leaf that will seriously be infected by black peach aphid (myzus persicae) immerses in the active agent preparations of desired concn to be handled.
After a period of time of determining, determine lethality with %.100% means all aphids is killed; 0% means and does not have aphid to be killed.
In this experiment, the application's following bond is compared with individualized compound and is shown synergistic effect:
Table A
The plant destructive insect
The black peach aphid test
| Active component | Concentration/ppm | Drug effect/% after 6 days |
| Different metsulfovax | 500 | 0 |
| Thiophene worm quinoline | 0.8 | 45 |
| Different metsulfovax of the present invention+thiophene worm quinoline (625: 1) | 500+0.8 | obs.* cal.** 95 45 |
*
Obs.The desinsection drug effect of=actual measurement
*
Cal.=use the drug effect of Colby formula calculating
Embodiment B
The chrysomelid test of horseradish ape
Solvent: 7 weight portion dimethyl formamides
Emulsifier: 2 weight portion alkylaryl polyglycol ethers
For preparing suitable active agent preparations,, and dope is diluted to desired concn with the water that contains emulsifier with the reactive compound of 1 weight portion and the solvent and the emulsifier of described amount.
Wild cabbage (brassica oleracea) leaf is immersed handle in the active agent preparations of desired concn and when leaf is still moistening, infect with the larva of horseradish ape chrysomelid (Phaedoncochleariae).
After a period of time of determining, determine lethality with %.100% means all mealworms is killed; 0% means and does not have mealworm to be killed.
In this test, the application's following bond is compared with individualized compound and is shown synergistic effect:
Table B
The plant destructive insect
The chrysomelid test of horseradish ape
| Active component | Concentration/ppm | Drug effect/% after 6 days |
| Different metsulfovax | 500 | 0 |
| Thiophene worm quinoline | 4 | 0 |
| Different metsulfovax of the present invention+thiophene worm quinoline (125: 1) | 500+4 | obs.* cal.** 30 0 |
*
Obs.The desinsection drug effect of=actual measurement
*
Cal.The drug effect that=usefulness Colby formula calculates
Embodiment C
The diamond-back moth test
Solvent: 7 weight portion dimethyl formamides
Emulsifier: 2 weight portion alkylaryl polyglycol ethers
For preparing suitable active agent preparations,, and dope is diluted to desired concn with the water that contains emulsifier with the reactive compound of 1 weight portion and the solvent and the emulsifier of described amount.
Wild cabbage (brassica oleracea) leaf is immersed handle in the active agent preparations of desired concn and when leaf is still moistening, infect with the larva of diamond-back moth (Plutella xylostella).
After a period of time of determining, determine lethality with %.100% means all larvas is killed; 0% means and does not have larva to be killed.
In this test, the application's following bond is compared with individualized compound and is shown synergistic effect:
Table C1
The plant destructive insect
The diamond-back moth test
| Active component | Concentration/ppm | Drug effect/% after 3 days |
| Different metsulfovax | 500 | 0 |
| Thiophene worm quinoline | 20 | 35 |
| Different metsulfovax of the present invention+thiophene worm quinoline (25: 1) | 500+20 | obs.* cal.** 60 35 |
*
Obs.The desinsection drug effect of=actual measurement
*
Cal.The drug effect that=usefulness Colby formula calculates
Table C2
The plant destructive insect
The diamond-back moth test
| ? Active component | Concentration/ppm | Drug effect/% after 6 days |
| Different metsulfovax | 1000 | 20 |
| SSF 126 | 1000 | 15 |
| Different metsulfovax+SSF 126 of the present invention (1: 1) | 1000+1000 | obs.* cal.** 55 32 |
*
Obs.The desinsection drug effect of=actual measurement
*
Cal.The drug effect that=usefulness Colby formula calculates
Embodiment D
Handle rest fungus test (wheat)/preventative
Solvent: 50 weight portion N, dinethylformamide
Emulsifier: 1 weight portion alkylaryl polyglycol ether
For preparing suitable active agent preparations, with the reactive compound of 1 weight portion and the solvent and the emulsifier of described amount, and water is diluted to desired concn with dope.
For carrying out the prophylactic activity test, in the spore suspension of puccinia triticinia (Puccinia triticina) in 0.1% concentration aqueous agar solution, immature plant is inoculated.After sprayed coating becomes dry, spray plant with described rate of application with active agent preparations.Under the relative atmospheric humidity with 100% plant was kept in incubator 24 hours down at 20 ℃.
About 20 ℃ with about 80% relative atmospheric humidity under plant is put into the greenhouse to promote the growth of rust warts.
Inoculate and after 10 days this test is assessed.0% means the drug effect that is equivalent to control group, and 100% drug effect means and do not observe disease.
Table D1
Handle rest fungus test (wheat)/preventative
| The combinations of compounds of invention:The substantial activity of reactive compound | |||||
| With the Colby formula | Mixed proportion | ||||
Embodiment E
Piricularia oryzae test (rice)/preventative
Solvent: 50 weight portion N, dinethylformamide
Emulsifier: 1 weight portion alkylaryl polyglycol ether
For preparing suitable active agent preparations, with the reactive compound of 1 weight portion and the solvent and the emulsifier of described amount, and water is diluted to desired concn with dope.
For carrying out the prophylactic activity test, spray immature plant with described rate of application with active agent preparations.After sprayed coating becomes dry, with the conidial suspension sprinkling plant of piricularia oryzae (Pyricularia oryzae).Subsequently plant is put into 100% relative atmospheric humidity, 25 ℃ greenhouse.
Inoculate and after 10 days this test is assessed.0% means the drug effect that is equivalent to control group, and 100% drug effect means and do not observe disease.
Table E
Piricularia oryzae test (rice)/preventative
| Combinations of compounds of the present invention: | |||||
| Mixed proportion | Rate of application/the ppm of reactive compound | Actual drug effect/% | Desired value with the calculating of Colby formula | ||
| Different metsulfovax+SSF 126 | ?} | 1∶1 | 25+25 | 100 | 79 |
| Different metsulfovax+thiophene fluorine bacterium amine | ?} | 1∶1 | 25+25 | 70 | 44 |
Claims (18)
1. a bond contains
(A) the different metsulfovax of formula (I)
With another kind of insecticidal active compound (B) thiophene worm quinoline, it is characterized in that it is 1: 625 to 625: 1 blending ingredients (A) that described bond contains weight ratio: (B).
2. the bond of claim 1 is a kind of bactericidal activity bond.
3. the bond of claim 1 is a kind of insecticidal activity bond.
4. composition contains among the claim 1-3 each a kind of bond.
5. the composition of claim 4 also contains auxiliary agent, solvent, carrier, surfactant or filler.
6. the method for the phytopathogenic fungi of therapeutic or preventative control plant or crop, this method comprises the fruit that each a kind of microbicide compositions in claim 4 and 5 is applied to seed, plant or plant, perhaps is applied to the soil that plant growing maybe will be grown.
7. the method for claim 6 comprises simultaneously or uses blending ingredients (A) and (B) successively.
8. the method for claim 7, wherein the amount of each bond/composition is 0.1g/ha to 10kg/ha for leaf and soil treatment among the claim 1-5, is 2 to 200g/100kg seeds for seed treatment.
9. the method for claim 6, wherein the amount of each bond/composition is 0.1g/ha to 10kg/ha for leaf and soil treatment among the claim 1-5, is 2 to 200g/100kg seeds for seed treatment.
10. the method for the insect of therapeutic or preventative control plant or crop, this method comprises the fruit that each a kind of insecticides in claim 4 and 5 is applied to seed, plant or plant, perhaps is applied to the soil that plant growing maybe will be grown.
11. the method for claim 10 comprises simultaneously or uses blending ingredients (A) and (B) successively.
12. the method for claim 11, wherein the amount of each bond/composition is 0.1g/ha to 10kg/ha for leaf and soil treatment among the claim 1-5, is 2 to 200g/100kg seeds for seed treatment.
13. the method for claim 10, wherein the amount of each bond/composition is 0.1g/ha to 10kg/ha for leaf and soil treatment among the claim 1-5, is 2 to 200g/100kg seeds for seed treatment.
14. each bond is used to handle the purposes of seed among the claim 1-3.
15. the purposes of claim 14 is used to handle transgenic seed.
16. bud and the leaf of protection seed and/or the plant that grown up to by seed make its method of avoiding insect or fungal damage, this method comprises with each a kind of bond among the claim 1-3 handles unseeded seed.
17. the method for claim 16, wherein said seed is handled with compound (A) when handling with compound (B).
18. the method for claim 16, wherein said seed was handled with compound (A) in the time different with using compound (B) processing.
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| EP2070416A1 (en) * | 2007-12-11 | 2009-06-17 | Bayer CropScience AG | Use of substance combinations for combating animal pests |
| EP2366289A1 (en) * | 2010-03-18 | 2011-09-21 | Basf Se | Synergistic fungicidal mixtures |
| CN103749522B (en) * | 2012-07-30 | 2015-09-09 | 陕西上格之路生物科学有限公司 | The bactericidal composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate-containing and acid amide fungicides |
| AR093996A1 (en) * | 2012-12-18 | 2015-07-01 | Bayer Cropscience Ag | BACTERICIDAL COMBINATIONS AND BINARY FUNGICIDES |
| CN105994317A (en) * | 2016-07-28 | 2016-10-12 | 河北博嘉农业有限公司 | Agricultural sterilizing composition containing isotianil and thifluzamide |
| CN109439606B (en) * | 2018-11-14 | 2022-06-28 | 中国科学院青岛生物能源与过程研究所 | Genetically engineered bacterium for increasing phloroglucinol yield and construction method and application thereof |
| CN114588070A (en) * | 2022-03-03 | 2022-06-07 | 深圳亿汀生物有限公司 | Composition for dynamically adjusting water-oil balance of skin to achieve rapid relief and application thereof |
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