Isolation and Characterization of Di-(2-ethylhexyl) Phthalate from the Leaves of Combretum micranthum (Altum) Combretaceae

Authors

  • Halilu, M.E. Usmanu Danfodiyo University, Sokoto
  • Yahaya, M. Usmanu Danfodiyo University, Sokoto
  • Dangoggo, S.M Usmanu Danfodiyo University, Sokoto
  • Umar, K.J. Usmanu Danfodiyo University, Sokoto
  • Ibrahim, G. Ahmadu Bello University, Zaria
  • Abdullahi, M. I. Usmanu Danfodiyo University, Sokoto
  • Uba, A. Usmanu Danfodiyo University, Sokoto
  • Baburo, S.I.B. Usmanu Danfodiyo University, Sokoto
  • Garba, M.A. Shehu Idris College of Health Sciences and Technology, Makarfi, Kaduna
  • Yusuf, A. J. Usmanu Danfodiyo University, Sokoto

Keywords:

Combretum micranthum, Di-(2-ethylhexyl) phthalate, preparative TLC, Extraction, Analysis

Abstract

Combretum micranthum is a medicinal plant used in traditional medicine for treatment of wounds, sores, diarrhoea, pain, fever and skin infections. This study was aimed at isolation and characterization of compounds from the leaves of Combretum micranthum. The pulverized leaves of the plant were gradiently extracted with hexane, ethyl acetate and methanol using soxhlet apparatus. The isolation of the compound was done using silica gel gravity column chromatography and preparative thin layer chromatography which yielded yellow compound ‘A’. The characterization of the isolated compound was carried out using 13C-NMR, 1H-NMR and GC-MS. Data obtained from the spectral analyses, suggested the compound to be di-(2-ethylhexyl) phthalate.

Author Biographies

Halilu, M.E., Usmanu Danfodiyo University, Sokoto

Department of Pharmacognosy and Ethnopharmacy, Usmanu Danfodiyo University, Sokoto,
Nigeria.

Yahaya, M., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.

Dangoggo, S.M, Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.

Umar, K.J., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.

Ibrahim, G., Ahmadu Bello University, Zaria

Department of Pharmacognosy and Drug Development, Ahmadu Bello University, Zaria,
Nigeria.

Abdullahi, M. I., Usmanu Danfodiyo University, Sokoto

Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University,
Sokoto, Nigeria.

Uba, A., Usmanu Danfodiyo University, Sokoto

Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University,
Sokoto, Nigeria.

Baburo, S.I.B., Usmanu Danfodiyo University, Sokoto

Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.

Garba, M.A., Shehu Idris College of Health Sciences and Technology, Makarfi, Kaduna

Shehu Idris College of Health Sciences and Technology, Makarfi, Kaduna, Nigeria.

Yusuf, A. J., Usmanu Danfodiyo University, Sokoto

Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University,
Sokoto, Nigeria.

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Published

2016-06-25

How to Cite

Halilu, M.E., Yahaya, M., Dangoggo, S.M, Umar, K.J., Ibrahim, G., Abdullahi, M. I., Uba, A., Baburo, S.I.B., Garba, M.A., & Yusuf, A. J. (2016). Isolation and Characterization of Di-(2-ethylhexyl) Phthalate from the Leaves of Combretum micranthum (Altum) Combretaceae. International Journal of Science for Global Sustainability, 2(2), 6. Retrieved from https://fugus-ijsgs.com.ng/index.php/ijsgs/article/view/251

Issue

Vol. 2 No. 2 (2016): INTERNATIONAL JOURNAL OF SCIENCE FOR GLOBAL SUSTAINABILITY (IJSGS)

Section

Articles

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