Table 1.
NMR spectroscopic data (CD3OD) of xinghaiamine Aa
Figure 1.
Production of a family of compounds with unique UV spectra by S. xinghaiensis. 1a
, HPLC profile of fermentation crude extract produced by S. xinghaiensis. The elution was monitored at 254 nm at a flow rate of 0.85 ml/min. 1b, UV absorption of the compound family. Compound E was named as xinghaiamine A.
Figure 2.
Proposed chemical structure of xinghaiamine A.
Figure 3.
Selected 1H-1H COSY (bold lines) and HMBC (red arrows) correlations of xinghaiamine A.
Table 2.
Antimicrobial activities of xinghaiamine A (MIC, µM) against the test strains.
Table 3.
In vitro cytotoxicity of xinghaiamine A (IC50 µM) against four human cancer cell lines.