Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
2009, Haemophilia
Experimental and Therapeutic Medicine
Current practices in haemophilic patients undergoing orthopedic surgery ‑ a systematic review2020 •
2022 •
2005 •
2009 •
Seminars in Hematology
Controversies and Challenges in Elective Orthopedic Surgery in Patients With Hemophilia and Inhibitors2008 •
2009 •
IP Innovative Publication Pvt. Ltd.
Inadvertent surgeries for patients with haemophilia -Emergent need for creating awarenessIntroduction: Majority of patients with hemophilia (PwH) has musculoskeletal (MSK) abnormalities and a large proportion of surgeries done in PwH are for MSK related complications. Often PwH have their initial presentation to orthopedicians with joint swelling even prior to bleeding from any other sites. Yet, haemophilia is an under-recognized entity among orthopedicians. Materials & Methods: This is a retrospective analysis of institutional haemophilia registry data of patients who has been operated for different MSK related abnormalities with special focus on those patients inadvertently operated by orthopedic surgeons without a prior diagnosis of haemophilia. Pre-operative evaluation and circumstances which led to the predicament of those patients were reviewed. All patients subsequently underwent a full coagulation work up including factor assay and inhibitor screen on suspecting a bleeding diathesis. Results: Out of a total 212 patients in the registry, 32 (15%) patients required surgical intervention and 16 (50%) of them were for MSK complications. Eleven (69%) patients underwent elective procedures with prior work up and five 5 (31%) patients underwent orthopaedic procedures inadvertently without a prior diagnosis of haemophilia. All the 5 patients (Haemophilia A-3 and Haemophilia B-2) achieved haemostasis with replacement therapy with varied surgical outcomes. Conclusions: Hemophilic arthropathy must be considered as a differential diagnosis in mono-articular arthritis. Careful elicitation of history and appropriate preoperative screening with prothrombin time (PT) and activated partial thromboplastin time (aPTT) is the antecedent to make a definitive diagnosis in a patient with suspected increased risk of bleeding.
2008 •
Although most surgical and invasive procedures can be performed safely in patients with haemophilia, the optimal level and duration of replacement therapy required to prevent bleeding complications have not been established conclusively. For providing more insight into optimal therapy during invasive procedures, a literature review of surgical procedures in patients with haemophilia was conducted. Concomitantly, current practice was surveyed in 26 European Haemophilia Comprehensive Care Centres, representing 15 different countries. The review identified 110 original papers published between 1965 and 2007. Of these, only two studies were randomized controlled trials. Target levels and the duration of replacement therapy in the published studies were as follows. For major orthopaedic surgery: preoperative targets were 80-90%; postoperative targets showed a high degree of variation, with trough levels ranging from 20% to 80%, duration 10-14 days; for liver biopsy, 70-100%, 1-7 days; to...
Revista Argentina De Cardiologia
Células embrionarias para regeneración miocárdica2009 •
Revista Historia de la Educación Colombiana
Universidad: del capital humano a un modelo de empresa en la educación superiorJournal of Waste Management
Contribution of Recycling of Municipal Solid Waste to the Social Inclusion in Brazil2004 •
Psychiatric Bulletin
Psychiatrists' and nurses' views of mental health nurse supplementary prescribing: a survey2008 •
1986 •
Advances in Intelligent Systems and Computing
Breast MRI Tumour Segmentation Using Modified Automatic Seeded Region Growing Based on Particle Swarm Optimization Image Clustering2013 •
Cogitare Enfermagem
Enfermeiras No Rito De Passagem De Getúlio Dos Santos (1929)2013 •
Revue ouverte d’ingénierie des systèmes d’information
Produire et socialiser la connaissance : la visualisation des données au CIEU2020 •
Journal of Experimental Biology
Calcium-regulated fusion of yolk granules is important for yolk degradation during early embryogenesis of Rhodnius prolixus Stahl2007 •
Accounting Education
Drivers of Teaching Effectiveness: Views from Accounting Educator Exemplars in Australia2014 •
Revista Kairós : Gerontologia
Relação entre a espiritualidade/religiosidade e a funcionalidade de idosos: uma revisão sistemática2019 •
2022 •
Handbook of Topological Fixed Point Theory
Fixed Point Theory of Multivalued Weighted MapsNeurourology and Urodynamics
Prognostic indicators of poor short‐term outcome of physiotherapy intervention in women with stress urinary incontinence2009 •
Frontiers in Cellular and Infection Microbiology
Life and Death of mRNA Molecules in Entamoeba histolytica2018 •
Grantee Submission
Discrepancies in Parent and Teacher Ratings of Low-Income Preschooler's Social Skills2016 •
Accounts of Chemical Research
Dichlorosilylene: A High Temperature Transient Species to an Indispensable Building Block2012 •
Interscience management review
Effective Time Management Skills for Today’s Young Professionals:- A Brief Note2008 •