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Heracleum persicum: chemical composition, biological activities and potential uses in poultry nutrition

Published online by Cambridge University Press:  29 April 2019

L. CHANGXING ,
D. DONGFANG ,
Z. LIXUE ,
M. SAEED ,
M. ALAGAWANY ,
M.R. FARAG ,
M. CHENLING  and
L. JIANHUA
L. CHANGXING
Affiliation:
Department of Human Anatomy, Medical College of Qinghai University, 810000 Xining, China
D. DONGFANG
Affiliation:
Department of Human Anatomy, Medical College of Qinghai University, 810000 Xining, China
Z. LIXUE
Affiliation:
Department of Physiology, Medical College of Northwest Minzu University, 730000 Lanzhou, Gansu, China
M. SAEED
Affiliation:
Department of Animal Nutrition, Cholistan University of Veterinary and Animal Sciences, Bahawalpur 63100, Pakistan
M. ALAGAWANY*
Affiliation:
Poultry Department, Faculty of Agriculture, Zagazig University, 44511 Zagazig, Egypt
M.R. FARAG
Affiliation:
Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt
M. CHENLING*
Affiliation:
Department of Respiratory, Fourth People's Hospital of Qinghai Province, 810000 Xining, China
L. JIANHUA*
Affiliation:
Department of Human Anatomy, Medical College of Qinghai University, 810000 Xining, China
*
Corresponding authors: dr.mahmoud.alagwany@gmail.com; 2170507919@qq.com, qhljh001@163.com
Corresponding authors: dr.mahmoud.alagwany@gmail.com; 2170507919@qq.com, qhljh001@163.com
Corresponding authors: dr.mahmoud.alagwany@gmail.com; 2170507919@qq.com, qhljh001@163.com
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Abstract

Heracleum persicum (golpar) is an endemic medicinal plant that is commonly known as hogweed or Persian hogweed. It contains flavonoids and furanocoumarins that probably could stimulate both cell- and antibody-mediated immune responses. Besides, golpar has a substantial immunostimulatory effect on beta-lymphocytes and macrophages that played important role in antibody synthesis. Its extract at a supplementation level of 1-2.5 ml/l in drinking water showed a remarkable increase in the total immunoglobulins (Ig) (70%), immunoglobulin G (IgG) (100%) and immunoglobulin M (IgM) (94%) titres and an increase in antibody titre against Newcastle disease virus (96%) in broilers. In addition, supplementation positively affected the feed intake (9.4%), weight gain (14.7%) and food conversion ratio (FCR) (8.7%) in broilers. Moreover, in several studies, it has potential as an antifungal, antidiabetic, hypocholesterolaemic and growth enhancer agent; which endorsed its extensive contents of phytochemicals (terpenoids, triterpenes, furanocoumarins, volatile substances, flavonoids and alkaloids). It has a positive effect on the levels of glutathione (GSH), peroxidation lipids (MDA), the total antioxidant capacity of plasma or ferric reducing ability of plasma (FRAP) and glutathione s-transferase (GST), in addition to modulatory effects on liver enzymes including alanine transferase (ALT) and aspartate transferase (AST). After reviewing the published literature, it was apparent that golpar has multidimensional biological effects. Nevertheless, little research is available on the effects of golpar on productive performance and other health-related parameters in avian species. Hence, this review encourages veterinarians and poultry researcher to undertake further work to demonstrate the promising beneficial effects of golpar at effective levels to potentially replace the synthetic antibiotic growth promoters in commercial poultry diets.

Keywords

Golpar (Heracleum persicum)herbfeed supplementpoultry
Type
Review
Information
World's Poultry Science Journal , Volume 75 , Issue 2 , June 2019 , pp. 207 - 218
Copyright
Copyright © World's Poultry Science Association 2019 

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