Abstract
This evergreen aromatic tree is indigenous to southwest China, and Vietnam. It had been used in China and Japan for a long time, but was not known to Indians and Persians, and was introduced to Europe in the sixteenth century. In TCM it is described as stomachic and stimulant, and used to dispel cold, regulate the flow of Qi and to relieve pain. In European medicine also, it is described as aromatic, stimulant and carminative. It is best used in the form of infusion. An herbal tea or infusion is used to treat colic pain in infants in many cultures. Anise oil is also applied to the abdomen of children to relieve colicky pains, to joints in rheumatism, and around the ear in cases of earache. Three neurotropic sesquiterpenoids, veranisatins A–C, were isolated from star anise . Volatiles, secoprezizaane-type sesquiterpenes, phenylpropanoids, phenylpropanoid glucoside, phytoquinoids, lignans, flavonoids, and illiciumflavane acid have been reported from the fruits. Substantial antibacterial activity of supercritical CO2 and ethanol extracts of fruits against clinical drug-resistant isolates, including A. baumannii, P. aeruginosa, and MRSA strains was reported. Anise oil exhibited in vitro virucidal activity against HSV-2, aciclovir-sensitive HSV-1 and an aciclovir-resistant clinical HSV-1 isolate as well as an aciclovir-resistant strain. Methanol fruit extract prolonged phenobarbitone-induced sleeping time, reduced locomotor activity, and produced alteration in general behavior pattern, and anxiolytic effects without significantly altering motor coordination.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bhadra S, Mukherjee PK, Kumar NS, Bandyopadhyay A. Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits. Fitoterapia. 2011;82:342–6.
Biessels GJ, Vermeij FH, Leijten FS. Epileptic seizure after a cup of tea: intoxication with Japanese star anise. Ned Tijdschr Geneeskd. 2002;146:808–11 (Dutch).
Chouksey D, Upmanyu N, Pawar RS. Central nervous system activity of Illicium verum fruit extracts. Asian Pac J Trop Med. 2013;6:869–75.
De M, De AK, Sen P, Banerjee AB. Antimicrobial properties of star anise (Illicium verum Hook. f.). Phytother Res. 2002;16:94–5.
Garzo Fernández C, Gómez Pintado P, Barrasa Blanco A, et al. Cases of neurological symptoms associated with star anise consumption used as a carminative. An Esp Pediatr. 2002;57:290–4 (Spanish).
Gil Campos M, Pérez Navero JL, Ibarra De La Rosa I. Convulsive status secondary to star anise poisoning in a neonate. An Esp Pediatr. 2002;57:366–8 (Spanish).
Huang Y, Zhao J, Zhou L, et al. Antifungal activity of the essential oil of Illicium verum fruit and its main component trans-anethole. Molecules. 2010;15:7558–69.
Ize-Ludlow D, Ragone S, Bernstein JN, et al. Chemical composition of Chinese star anise (Illicium verum) and neurotoxicity in infants. JAMA. 2004;291:562–3.
Ize-Ludlow D, Ragone S, Bruck IS, et al. Neurotoxicities in infants seen with the consumption of star anise tea. Pediatrics. 2004;114:e653–6.
Johanns ES, van der Kolk LE, van Gemert HM, et al. An epidemic of epileptic seizures after consumption of herbal tea. Ned Tijdschr Geneeskd. 2002;146:813–6 (Dutch).
Joshi VC, Srinivas PV, Khan IA. Rapid and easy identification of Illicium verum Hook. f. and its adulterant Illicium anisatum Linn. by fluorescent microscopy and gas chromatography. J AOAC Int. 2005;88:703–6.
Kakemoto E, Okuyama E, Nagata K, Ozoe Y. Interaction of anisatin with rat brain gamma-aminobutyric acid A receptors: allosteric modulation by competitive antagonists. Biochem Pharmacol. 1999;58:617–21.
Koch C, Reichling J, Kehm R, et al. Efficacy of anise oil, dwarf-pine oil and chamomile oil against thymidine-kinase-positive and thymidine-kinase-negative herpesviruses. J Pharm Pharmacol. 2008;60:1545–50.
Koch C, Reichling J, Schneele J, Schnitzler P. Inhibitory effect of essential oils against herpes simplex virus type 2. Phytomedicine. 2008;15:71–8.
Lee SW, Li G, Lee KS, et al. A new phenylpropanoid glucoside from the fruits of Illicium verum. Arch Pharm Res. 2003;26:591–3.
Madden GR, Schmitz KH, Fullerton K. A case of infantile star anise toxicity. Pediatr Emerg Care. 2012;28:284–5.
Matsui T, Ito C, Itoigawa M, et al. Anti-inflammatory activity of phenylpropanoids and phytoquinoids from Illicium species in RBL-2H3 cells. Planta Med. 2007;73:662–5.
Minodier P, Pommier P, Moulène E, et al. Star anise poisoning in infants. Arch Pediatr. 2003;10:619–21 (French).
Miyagawa M, Satou T, Yukimune C, et al. Anxiolytic-like effect of Illicium verum fruit oil, trans-anethole and related compounds in mice. Phytother Res. 2014;28:1710–2.
Nakamura T, Okuyama E, Yamazaki M. Neurotropic components from star anise (Illicium verum Hook. fil.). Chem Pharm Bull (Tokyo). 1996;44:1908–14.
Okuyama E, Nakamura T, Yamazaki M. Convulsants from star anise (Illicium verum Hook. f.). Chem Pharm Bull (Tokyo). 1993;41:1670–1.
Park SH, Sung YY, Nho KJ, Kim HK. Protective activity ethanol extract of the fruits of Illicium verum against atherogenesis in apolipoprotein E knockout mice. BMC Complement Altern Med. 2015;15:232.
Song WY, Ma YB, Bai X, et al. Two new compounds and anti-HIV active constituents from Illicium verum. Planta Med. 2007;73:372–5.
Sung YY, Yang WK, Lee AY, et al. Topical application of an ethanol extract prepared from Illicium verum suppresses atopic dermatitis in NC/Nga mice. J Ethnopharmacol. 2012;144:151–9.
Sy LK, Brown GD. Novel phenylpropanoids and lignans from Illicium verum. J Nat Prod. 1998;61:987–92.
Wang GW, Hu WT, Huang BK, Qin LP. Illicium verum: a review on its botany, traditional use, chemistry and pharmacology. J Ethnopharmacol. 2011;136:10–20.
Wu LD, Xiong CL, Chen ZZ, et al. A new flavane acid from the fruits of Illicium verum. Nat Prod Res. 2016;30:1585–90.
Yadav AS, Bhatnagar D. Chemopreventive effect of star anise in N-nitrosodiethylamine initiated and phenobarbital promoted hepato-carcinogenesis. Chem Biol Interact. 2007;169:207–14.
Yadav AS, Bhatnagar D. Inhibition of iron induced lipid peroxidation and antioxidant activity of Indian spices and Acacia in vitro. Plant Foods Hum Nutr. 2010;65:18–24.
Yang JF, Yang CH, Chang HW, et al. Chemical composition and antibacterial activities of Illicium verum against antibiotic-resistant pathogens. J Med Food. 2010;13:1254–62.
Zhou J, Lü G, Zhong X, Wen H. Quantitative determination of anethole in the fruit of Illicium verum from various places of Guangxi province. Zhong Yao Cai. 2005;28:106–7 (Chinese).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Akbar, S. (2020). Illicium verum Hook.f. (Schisandraceae). In: Handbook of 200 Medicinal Plants. Springer, Cham. https://doi.org/10.1007/978-3-030-16807-0_111
Download citation
DOI: https://doi.org/10.1007/978-3-030-16807-0_111
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-16806-3
Online ISBN: 978-3-030-16807-0
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)