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Minthostachys verticillata (Griseb.) Epling

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Medicinal and Aromatic Plants of South America Vol. 2

Part of the book series: Medicinal and Aromatic Plants of the World ((MAPW,volume 7))

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Abstract

The objective of this review is to provide an overall description of the taxonomy, morphology, uses, active principles and future prospects of the endemic Argentinean aromatic plant, locally known as “peperina” (Minthostachys verticillata). This species is an important plant that has been frequently enjoyed and used by the people of central Argentina. It was perhaps the initial interest of the indigenous population and settlers paid to this remarkable plant that led to uses and applications in many commercial products. Due to over-collection from the wild by a population increasingly interested in natural plant products, to date “peperina” has become a threatened species. This work seeks to generate and reignite interest in the use and conservation of this important medicinal and aromatic shrub from Argentina.

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References

  • ANMAT (Administración Nacional de Medicamentos, Alimentos y Tecnología Médica) (2015) Ministerio de Salud, Argentina. Dispos. 8357/2015

    Google Scholar 

  • ANMAT (Administración Nacional de Medicamentos, Alimentos y Tecnología Médica) (2019) Código Alimentario Argentino. Ministerio de Salud. Argentina

    Google Scholar 

  • Arias Toledo B (2009) Diversidad de usos, prácticas de recolección y diferencias según género y edad en el uso de plantas medicinales en Córdoba, Argentina. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 8(5):389–401

    Google Scholar 

  • Bandoni AL, López MA, Juárez MA, Elechosa MA, van Baren C, Di Leo Lira P (2002). Seasonal variations in the composition of the essential oil of peperina (Minthostachys mollis (Kunth) Griseb.) from a local population of the province of Córdoba, Argentina. Essenze Derivati Agrumari 72(1):11–14

    Google Scholar 

  • Barboza GE, Bonzani N, Filippa EM, Luján MC, Morero R, Bugatti M, Decolatti N, Ariza Espinar L (2001) Atlas histo-morfológico de plantas de interés medicinal de uso corriente en Argentina. Editorial de la Universidad Nacional de Córdoba, Córdoba, Argentina, 212 pp

    Google Scholar 

  • Barboza GE, Cantero JJ, Nunez C, Pacciaroni A, Ariza Espinar L (2009) Medicinal plants: a general review and a phytochemical and ethnopharmacological screening of the native Argentine Flora. Kurtziana 34(1–2):7–365

    Google Scholar 

  • Cariddi LN, Moser M, Zygadlo JA, Sabini IL, Maldonado A (2007a) Pure compounds isolated of essential oil of Minthostachys verticillata (Griseb.) Epling like polyclonal activators in vitro. Bol Latinoam Caribe Plant Med Aromáticas 6(5):236–237

    Google Scholar 

  • Cariddi LN, Panero A, Demo MS, Grosso M, Zygadlo J, Sabini LI, Maldonado AM (2007b) Inhibition of immediate-type allergic reaction by Minthostachys verticillata (Griseb.) Epling essential oil. J Essent Oil Res 19:190–196

    Article  CAS  Google Scholar 

  • Cariddi L, Moser M, Andrada M, Demo M, Zygadlo J, Sabini L, Maldonado A (2009) The effect of Minthostachys verticillata essential oil on the immune response of patients allergic to dust mites. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 8(3):224–233

    CAS  Google Scholar 

  • Cariddi L, Escobar F, Moser M, Panero A, Alaniz F, Zygadlo J, Sabini L, Maldonado A (2011) Monoterpenes isolated from Minthostachys verticillata (Griseb.) Epling essential oil modulates immediate-type hypersensitivity responses in vitro and in vivo. Planta Med 77(15):1687–1694

    Article  CAS  Google Scholar 

  • Chebel AD, Koroch AR, Juliani HR, Juliani HR Jr, Trippi VS (1998) Micropropagation of Minthostachys mollis (H.B.K) Griseb. and essential oil composition of clonally propagated plants. In Vitro Plant Cell Dev Biol 34:249–251

    Article  CAS  Google Scholar 

  • Croteau RB, Davis EM, Ringer K, Wildung MR (2005) Menthol biosynthesis and molecular genetics. Naturwissenschaften 92:562–577

    Article  CAS  Google Scholar 

  • Dade MM, Fioravanti DE, Schinella CR, Tournier HA (2009) Total antioxidant capacity and polyphenol content of 21 aqueous extracts obtained from native plants of Traslasierra valley (Argentina). Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 8(6):529–539

    CAS  Google Scholar 

  • Damiani N, Gende LB, Maggi MD, Palacios S, Marcangeli JA, Eguaras MJ (2011) Repellent and acaricidal effects of botanical extracts on Varroa destructor. Parasitol Res 108:79–86

    Article  Google Scholar 

  • Escobar FM, Cariddi LN, Sabini MC, Reinoso E, Sutil SB, Torres CV, Zanon SM, Sabini LI (2012) Lack of cytotoxic and genotoxic effects of Minthostachys verticillata essential oil: studies in vitro and in vivo. Food Chem Toxicol 50(9):3062–3067

    Article  CAS  Google Scholar 

  • Escobar FM, Sabini MC, Cariddi LN, Sabini LI, Manas F, Cristofolini A, Bagnis G, Gallucci MN, Cavaglieri LR (2015) Safety assessment of essential oil from Minthostachys verticillata (Griseb.) Epling (peperina): 90-days oral subchronic toxicity study in rats. Regul Toxicol Pharmacol 71:1–7

    Article  CAS  Google Scholar 

  • Glinos E, Condat E, Mulieri P, Ashworth L (2019) Essential dependence on wild pollination service: a medicinal plant under threat Minthostachys verticillata (Lamiaceae). Arthropod Plant Interact 13(6):865–874

    Article  Google Scholar 

  • INTA (Instituto Nacional de Tecnología Agropecuaria) (2009) Manual de recolección sustentable de plantas aromáticas nativas de la región central y noroeste de la Argentina. Ed. INTA, Buenos Aires, Argentina, 48 pp

    Google Scholar 

  • Juliani HR, Biurrun FN, Koroch AR, De Carli AG, Zygadlo JA (2007) The production of native and exotic herbs, medicinal and aromatic plants in Argentina. In: Janick J, Whipkey A (eds) Issues in new crops and new uses. Ed. Am Soc Hortic Sci (ASHS) Press, Alexandria, USA, pp 316–321

    Google Scholar 

  • Koroch AR, Zygadlo JA, Juliani HR (2007) Bioactivity of essential oils and their components. In: Berger RG (ed) Flavours and Fragrances. Chemistry, bioprocessing and sustainability. Springer, Berlin-Heidelberg, Germany, pp 87–115

    Chapter  Google Scholar 

  • Lang G, Buchbauer G (2012) A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. Flavour Fragr J 27:13–39

    Article  CAS  Google Scholar 

  • Martínez G (2015) Las Plantas en la Medicina Tradicional de las Sierras de Córdoba. Editorial Detodoslosmares. Capilla del Monte. Córdoba. Argentina, 210 pp

    Google Scholar 

  • Martínez GJ, Planchuelo AM, Fuentes E, Ojeda M (2006) A numeric index to establish conservation priorities for medicinal plants in the Paravachasca Valley, Córdoba, Argentina. Biodivers Conserv 15:2457–2475

    Article  Google Scholar 

  • Mora FD, Araque M, Rojas LB, Ramírez R, Silva B, Usubillaga A (2009) Chemical composition and in vitro antibacterial activity of the essential oil of Minthostachys mollis (Kunth) Griseb. Vaught from the Venezuelan Andes. Nat Prod Commun 4(7):997–1000

    CAS  PubMed  Google Scholar 

  • NTP (National Toxicology Program) (2001) Technical report on the toxicology and carcinogenesis studies of Pulegone in: F344/N rats and B6c3f1 mice (gavage studies). National Institutes of Health. NTP TR 563/NIH Publication No. 11-5905. Research Triangle Park, North Carolina, USA, 202 pp

    Google Scholar 

  • Ocaño SF (2017) Generación de una Población de “Peperina” Minthostachys verticillata (Griseb.) Epling, Mejorada por Sanidad, Rendimiento y Calidad de Aceites Esenciales. Thesis. Universidad Nacional de Córdoba. Escuela para Graduados. Facultad de Ciencias Agropecuarias. Córdoba, Argentina, 132 pp

    Google Scholar 

  • Ojeda MS (2011) La Peperina. Caracterización de poblaciones y avances en la domesticación. Editorial Académica Española. Córdoba, Argentina, 152 pp. ISBN 978-3-8454-8773-1

    Google Scholar 

  • Ojeda MS, Karlin UOT (2015) Plantas Aromáticas y Medicinales. Modelos para su Domesticación, Producción y Usos Sustentables. Editorial Universidad Nacional de Córdoba. Córdoba. Argentina, 183 pp

    Google Scholar 

  • Ojeda M, Coirini R, Cosiansi J, Zapata R, Zygadlo J (2001) Evaluation of variability in natural populations of peperina (Minthostachys mollis (Kunth.) Griseb.), an aromatic species from Argentina. Plant Genetic Resour Newsletter 126:27–30

    Google Scholar 

  • Palacios SM, Bertoni A, Rossi Y, Santander R, Urzúa A (2009) Insecticidal activity of essential oils from native medicinal plants of Central Argentina against the house fly, Musca domestica (L.). Parasitol Res 106:207–212

    Article  Google Scholar 

  • Rodríguez-Vaquero MJ, Vallejo CV, Aredes-Fernaández PA (2014) Biological activity of phenolic compounds from Argentinean herbs infusions. Open Confer Proc J 2014(5):1–7

    Article  Google Scholar 

  • Rossi YA, Canavoso L, Palacios SM (2012) Molecular response of Musca domestica L. to Minthostachys verticillata essential oil, (4R)(+)-pulegone and menthone. Fitoterapia 83:336–342

    Article  CAS  Google Scholar 

  • Scandaliaris M (2017). Caracterización morfo-histológica de las núculas y su valor taxonómico en Lamiaceae nativas de Argentina. Thesis. Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias. Córdoba, Argentina, 218 pp

    Google Scholar 

  • Scandaliaris M, Fuentes E, Lovey RJ (2007) Dos especies de Lamiáceas comercializadas en Córdoba (Argentina) bajo el nombre de “peperina”. Multequina 16:73–81

    Google Scholar 

  • Schmidt-Lebuhn AN (2008a) Revision of the genus Minthostachys (Labiatae). Mem N Y Bot Gard 98:1–78

    Google Scholar 

  • Schmidt-Lebuhn AN (2008b) Ethnobotany, biochemistry and pharmacology of Minthostachys (Lamiaceae). J Ethnopharmacol 118:343–353

    Article  CAS  Google Scholar 

  • The Plant List (2020) In Internet: http://www.theplantlist.org/tpl1.1/record/kew-128642. (Last access, May 2020)

  • van Baren CM, Di Leo Lira P, Elechosa MA, Molina AM, Juárez MA, Martínez A, Perelman S, Bandoni AL (2014) New insights into the chemical biodiversity of Minthostachys mollis in Argentina. Biochem Syst Ecol 57:374–383

    Article  Google Scholar 

  • Xifreda CC, Mallo AC, Fatta NA (2005) La calaminta (Melissa calamintha, Lamiaceae) cultivada como tapizante ornamental. Resúmenes de las VII Jornadas Nacionales de Floricultura. In electronic support. Trevelin, Chubut, Argentina

    Google Scholar 

  • Zygadlo JA, Maestri DM, Lamarque AL, Guzmán CA, Velasco-Negueruela A, Pérez-Alonso MJ, García-Vallejos MC, Grosso NR (1996) Essential oil variability of Minthostachys verticillata. Biochem Syst Ecol 24(4):319–323

    Article  CAS  Google Scholar 

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Acknowledgments

PCB is thankful to CONICET (Argentinean Council of Scientific and Technical Research) and the Office of Science and Technology of the National University of Córdoba (Argentina) (SECYT/UNC). HRJ and PCB are also thankful to the Fulbright Program (funded by the U.S. Department of State).

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Correspondence to H. Rodolfo Juliani .

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Juliani, H.R., Brunetti, P., Koroch, A.R. (2021). Minthostachys verticillata (Griseb.) Epling. In: Máthé, Á., Bandoni, A. (eds) Medicinal and Aromatic Plants of South America Vol. 2. Medicinal and Aromatic Plants of the World, vol 7. Springer, Cham. https://doi.org/10.1007/978-3-030-62818-5_28

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