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Baccharis tola Phil., B. boliviensis (Wedd.) Cabrera

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Medicinal and Aromatic Plants of South America Vol. 2

Part of the book series: Medicinal and Aromatic Plants of the World ((MAPW,volume 7))

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Abstract

The genus Baccharis, with approximately 500 species, is one of the largest genera of the family Asteraceae. Species of this genus are distributed mainly in the warm temperate and tropical regions of Brazil, Argentina, Colombia, Chile and Mexico. In Argentina, 96 species have been described. Baccharis tola and Baccharis boliviensis are used in traditional medicine, in Argentina. They are popularly known as “tola”, “tolilla”, “lejía” or “romerillo”. The occurrence and identification of flavonoids and terpenoids have been reported from these species. The scientific validation of its medicinal properties as antioxidants, anti-inflammatory and antibiotics/antifungal agents has been done. Some phytotherapeutic formulations for topical applications have been developed with the ethanolic extract of B. tola. Both B. boliviensis and B. tola seem to be promising species for regional development, in these countries, although farther studies are needed in order to elaborate the technology for its sustainable domestication and subsequent cultivation.

figure a

Baccharis tola ex Baccharis incarum (a. and b.) and Baccharis boliviensis (c. and d.). Photos: I Catiana Zampini, during the sample collection. Antofagasta de la Sierra, Catamarca, Argentina

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References

  • Abad MJ, Bermejo P (2007) Baccharis (Compositae): a review update. ARKIVOC 7:76–96

    Google Scholar 

  • Achike FI, Kwan C (2003) Nitric oxide, human disease and the herbal products that affect the nitric oxide signaling pathway. Clin Exp Pharmacol Physiol 30:605–615

    Article  CAS  PubMed  Google Scholar 

  • Alberto MR, Zampini IC, Isla MI (2009) Cyclooxygenase enzyme inhibitory activity of standardized hydroalcoholic extracts of four Asteraceae species from the argentine Puna. Brazilian J Med Biol Res 42(9):776–780

    Article  Google Scholar 

  • Aldunate C, Armesto J, Castro V, Villagrán C (1981) Estudio Etnobotánico en una Comunidad precordillerana de Antofagasta: Toconce. Bol Mus Nac Hist Nat Chile 38:183–223

    Google Scholar 

  • Alzirreca H, Cardozo A (1991) Valor de los alimentos para la ganadería andina. Serie técnica IBTA-CRSP. Convenio Universidad de California, Davis -IBTA La Paz, Bolivia. 35 pp

    Google Scholar 

  • Beck S (1985) Flórula ecológica de Bolivia. Ecol Boliv 6:1–41

    Google Scholar 

  • Borgnia M, Maggi A, Arriaga M, Aued B, Vilá B, Cassini MH (2006) Caracterización de la vegetación en la Reserva de Biosfera Laguna Blanca (Catamarca, Argentina). Ecol Austral 16:29–45

    Google Scholar 

  • Cabrera AL (1978) Flora de la Provincia de Jujuy. Colección Científica del INTA. Buenos Aires, Argentina. Parte X – Compositae, 231 pp

    Google Scholar 

  • Calle A, Yupanqui J, Flores Y, Almanza G (2012) Flavonoides de Baccharis boliviensis. Rev Boliv Quím 20:155–160

    Google Scholar 

  • Cantero JC, Nuñez CO, Bernardello G, Amuchástegui A, Mulko J, Brandolin P, Palchetti MV, Iparraguirre J, Virginil N, Ariza Espinar L (2019) Las plantas de importancia económica en Argentina. First Edition. Ed. UniRío Editora. Universidad Nacional de Río Cuarto, Córdoba, Argentina, 937 pp. https://botanicaargentina.org.ar/wp-content/uploads/2019/06/978-987-688-332-0-baja-resoluci%C3%B3n.pdf. (Last access, January 2020)

  • Carilla J, Grau A, Cuello S (2018) Vegetación de la Puna argentina. Serie Conservación de la Naturaleza 24: La Puna argentina: naturaleza y cultura 143–156

    Google Scholar 

  • Carrizo L (2011) Evaluación “in vitro” de la actividad antifúngica de extractos provenientes de especies del género Baccharis. Thesis. Universidad Nacional de Tucumán. Tucumán, Argentina. 116 pp

    Google Scholar 

  • Carrizo SL, Zampini C, Isla MI, van Gelderen A (2010) Evaluation “in vitro” of antifungal activity of Baccharis extracts on yeasts. BIOCELL 34(2)-ISSN 0327–9545 (print). ISSN 1667–5746 (electronic)

    Google Scholar 

  • Carrizo SL, Zampini IC, Sayago JE, Simirgiotis MJ, Bórquez J, Cuello AS, Isla MA (2020) Antifungal activity of phytotherapeutic preparation of Baccharis species from argentine Puna against clinically relevant fungi. J Ethnopharmacol 251(6):112553

    Article  CAS  PubMed  Google Scholar 

  • Castro M, Villagrán C, Arroyo M (1982) Estudio Etnobotánico en la precordillera y altiplano de Los Andes del norte de Chile (18–19 °S). In: Veloso A, Bustos E (ed) El Hombre y los Ecosistemas de Montañas. Tomo II. Ed. UNESCO, Santiago, Chile. pp 33–199

    Google Scholar 

  • Cazés Camarero PL (2000) Nombres vulgares de Asteraceae del herbario del Museo “Juan A. Domínguez” (Facultad de Farmacia y Bioquímica. UBA). Dominguezia 16(1):32

    Google Scholar 

  • Cazón A, de Viana M, Gianello J (2000) Identificación de un compuesto alelopático de Baccharis boliviensis (Asteraceae) y su efecto en la germinación de Trichocereus pasacana (Cactaceae). Rev Biol Trop 48(1):47–51

    Google Scholar 

  • Cazón A, de Viana M, Gianello JC (2002). Efecto fitotóxico de aleloquímicos de Baccharis boliviensis. Ecol Austral 12:73–78

    Google Scholar 

  • Cuello S (2006) Guía ilustrada de la Flora de Antofagasta de la Sierra, Catamarca. Ed. Facultad de Ciencias Naturales-Universidad Nacional de Tucumán, Tucumán, Argentina. 165 pp

    Google Scholar 

  • De Lucca M (1987) Diccionario Práctico Aymara-Español, Español-Aymara. Ed. Los Amigos del Libro, La Paz, Bolivia, 288 pp

    Google Scholar 

  • De Lucca M, Zalles J (1992) Flora medicinal boliviana. Diccionario enciclopédico. Ed. Los Amigos del Libro, La Paz, Bolivia, 498 pp

    Google Scholar 

  • Erazo S, Negrete R, Zaldívar M, Backhouse N, Delporte C, Silva I, Belmonte E, López-Pérez JL, San Feliciano A (2002) Methyl psilalate: a new antimicrobial metabolite from Psila boliviensis. Planta Med 68:66–67

    Article  CAS  PubMed  Google Scholar 

  • Faini FA, Castillo M, Torres MR (1982) Flavonoids of Baccharis incarum. J Nat Prod 45:501–502

    Article  CAS  Google Scholar 

  • Feresin GE, Tapia A, Bustos DA (2000) Antibacterial activity of some medicinal plants from San Juan, Argentina. Fitoterapia 71:429–432

    Article  CAS  PubMed  Google Scholar 

  • Galafassi G (1997) Actividad recolectora en pastores de altura (Laguna Blanca, Catamarca). Sup Antropol 32(1–2):397–426

    Google Scholar 

  • Givovich A, San Martín A, Castillo M (1986) Neo-clerodane diterpenoids from Baccharis incarum. Phytochemistry 25:2829–2831

    Article  CAS  Google Scholar 

  • Gonzaga Verdi L, Costa Brighente IM, Pizzolatti MG (2005) Gênero Baccharis (Asteraceae): Aspectos químicos, econômicos e biológicos. Quim Nova 28(1):85–94

    Article  Google Scholar 

  • González J, Sagua H, Araya J, Loyola A, Morales G, Pereira J, Estrada M (1990) In vitro activity of natural products against the trypomastigote form of Trypanosoma cruzi. Phytother Res 4:1–5

    Article  Google Scholar 

  • Haber A (1992) Pastores y pasturas. Recursos forrajeros en Antofagasta de la Sierra (Catamarca), en relación a la ocupación formativa. Shincal 2:15–23

    Google Scholar 

  • Herrera SY, Zampini IC, D’Almeida R, Boguetti H, Isla MI (2007) Supercritical fluid extraction of antioxidants compounds from Baccharis incarum: comparison with conventional extraction methods. Bol Latinoam Caribe Plant Med Aromat 6(5):250–252

    Google Scholar 

  • Lira J (1945) Diccionario Kechuwa-Español. Publicación 369, Instituto de Historia, Lingüística y Folklore, Ed. Universidad Nacional de Tucumán, Tucumán, Argentina. pp 748

    Google Scholar 

  • Mahady G (2005) Medicinal Plants for the Prevention and Treatment of Bacterial Infections. Curr Pharm Design 11(19):2405–2427

    Google Scholar 

  • Morales G, Mancilla A, Gallardo O, Trujillo R, Loyola L, Breton JL (1990) Diterpenoids and flavonoids from Baccharis boliviensis. Bol Soc Chil Quim 35:257–263

    CAS  Google Scholar 

  • Muñoz Pizarro C (1973) Chile: Plantas en Extinción. Ed. Universitaria. Santiago, Chile. 344 pp

    Google Scholar 

  • Murillo A (1861) Memoria sobre las plantas medicinales de Chile y uso que de ellas se hace en el país del país. Ed. Imprenta del Ferrocarril, Santiago, Chile. pp 583–645

    Google Scholar 

  • Nuño G, Zampini I, Ordóñez R, Alberto M, Arias M, Isla MI (2012) Antioxidant/antibacterial activities of a topical phytopharmaceutical formulation containing a standardized extract of Baccharis incarum, an extremophile plant species from argentine Puna. Phytother Res 26:1759–1767

    Article  PubMed  Google Scholar 

  • Pérez García F, Marín E, Adzet T, Cañigueral S (2001) Activity of plant extracts on the respiratory burst and the stress protein synthesis. Phytomed 8:31–38

    Article  Google Scholar 

  • Pérez F, Marin E, Adzet T (1995) The antiinflammatory effect of several composite from South America. Extracts in rats. Phytother Res 9:145–146

    Article  Google Scholar 

  • Rojo L, Benítez J, López J, Rojas M, Díaz P, Ordóñez J, Pastene E (2009) Antioxidant capacity and polyphenolic content of twelve traditionally used herbal medicinal infusions from the south American Andes. Bol Latinoam Caribe Plant Med Aromát 8(6):498–508

    CAS  Google Scholar 

  • Romagnoli M, Gómez-Cabrera MC, Perrelli MG, Biasi F, Pallardo FV, Sastre J, Poli G, Viña J (2010) Xanthine oxidase-induced oxidative stress causes activation of NF-κB and inflammation in the liver of type I diabetic rats. Free Rad Biol Med 49:171–177

    Article  CAS  PubMed  Google Scholar 

  • San Martín AS, Rovirosa J, Becker R, Castillo M (1980) Diterpenoids from Baccharis tola. Phytochemistry 19:1985–1987

    Article  Google Scholar 

  • San Martín AS, Rovirosa J, Castillo M (1983) Diterpenoids from Baccharis tola. Phytochemistry 22:1461–1463

    Article  Google Scholar 

  • San Martín A, Givovich A, Castillo M (1985) Neo-clerodane diterpenoids from Baccharis incarum. Phytochemistry 25:264–266

    Article  Google Scholar 

  • Simirgiotis MJ, Quispe C, Bórquez J, Mocan A, Sepúlveda B (2016) High resolution metabolite fingerprinting of the resin of Baccharis tola Phil. From the Atacama Desert and its antioxidant capacities. Ind Crop Prod 94:368–375

    Article  CAS  Google Scholar 

  • The Plant List (2020) Version 1.1. Published on the Internet: www.theplantlist.org. (Last access, January 2020)

  • Torres Carro R, Isla MI, Ríos JL, Giner RM, Alberto MR (2015) Anti-inflammatory properties of hydroalcoholic extracts of argentine Puna plants. Food Res Int 67:230–237

    Article  Google Scholar 

  • Torres Carro R, Isla MI, Thomas Valdes S, Jiménez Aspee F, Schmeda-Hirschmann G, Alberto MR (2017) Inhibition of pro-inflammatory enzymes by medicinal plants from the Argentinean highlands (Puna). J Ethnopharmacol 205:57–68

    Article  CAS  PubMed  Google Scholar 

  • Torres-Carro R, Yamile A, Rojas-Márquez JD, Stempin CC, Zampini IC, Isla MI, Alberto MR (2019) Argentinean Puna plants with in vitro antioxidant and anti-Inflammatory activities as a potential nutraceutical. J Food Sci 84(12):3352–3363

    Google Scholar 

  • Vidaurre PJ, Paniagua N, Moraes RM (2006). Etnobotánica en los Andes de Bolivia. In: Moraes M, Øllgaard B, Kvis LP, Borchsenius F, Balslev H: Botánica Económica de los Andes Centrales. Universidad Mayor de San Andrés, La Paz, Bolivia. pp 224–238

    Google Scholar 

  • Villagrán C, Romo M, Castro V (2003) Etnobotánica del sur de los Andes de la primera región de Chile: un enlace entre las culturas altiplánicas y las de quebradas altas del Loa superior. Chungara, Rev Antrop Chil 35(1):73–124

    Google Scholar 

  • Wickens G (1993) Vegetation and Ethnobotany of the Atacama Desert and adjacent Andes in northern Chile. Opera Bot 121:291–307

    Google Scholar 

  • Zampini IC, Vera N, Bardón A, Isla MI (2006) Antioxidant potential of Baccharis incarum: isolation of bioactive metabolites. Mol Med Chem 11:56–57

    Google Scholar 

  • Zampini IC, Vera N, Bardón A, Isla MI (2007) Antioxidant and antimicrobial flavonoid isolated from Baccharis incarum. Bol Latinoam Caribe Plant Med Aromát 6(5):292–294

    Google Scholar 

  • Zampini IC, Meson Gana J, Ordóñez RM, Sayago JE, Nieva Moreno MI, Isla MI (2008) Antioxidant and xanthine oxidase inhibitory activities of plant species from the argentine Puna (Antofagasta, Catamarca). Recent Progress in Med Plants 21:95–110

    Google Scholar 

  • Zampini IC, Isla MI, Schmeda-Hirschmann G (2009a) Antimicrobial and antioxidant compounds from the infusion and methanolic extract of Baccharis incarum (Wedd.) Perkins. J Chil Chem Soc 54(4):289–293

    Article  Google Scholar 

  • Zampini IC, Cuello S, Alberto MR, Ordóñez RM, D Almeida R, Solórzano E, Isla MI (2009b) Antimicrobial activity of selected plants from “the argentine Puna” against sensitive and multiresistant bacteria. J Ethnopharmacol 124(3):499–505

    Article  CAS  PubMed  Google Scholar 

  • Zdero CC, Bohlmann H, King RM, Robinson H (1986) Diterpene glycosides and other constituents from argentinian Baccharis species. Phytochemistry 25(12):2841–2855

    Article  CAS  Google Scholar 

  • Zdero CC, Bohlmann H, Solomon J, King RM, Robinson H (1989) Ent-clerodanes and other constituents from bolivian Baccharis species. Phytochemistry 28(2):531–542

    Article  CAS  Google Scholar 

Download references

Acknowledgments

The authors acknowledge the cooperation of the inhabitants of the studied areas and the financial support from the SCAIT-Universidad Nacional de Tucumán (PIUNT2018 G-637), the Agencia Nacional de Promoción Científica y Técnica (ANPCyT, PICT 2014- 3136 and PICT 2017- 4436) and the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET, PUE 2018- 0011).

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Authors and Affiliations

  1. Instituto de Bioprospección y Fisiología Vegetal (INBIOFIV, CONICET- Facultad de Ciencias Naturales e Instituto Miguel Lillo-Universidad Nacional de Tucumán), San Miguel de Tucumán, Argentina

    María Inés Isla, Mariana Leal, Silvana L. Carrizo & Iris C. Zampini

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  1. María Inés Isla
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  2. Mariana Leal
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  3. Silvana L. Carrizo
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  4. Iris C. Zampini
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Correspondence to María Inés Isla .

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  1. Faculty of Agr. & Food Sc., Széchenyi István University, Mosonmagyaróvár, Hungary

    Ákos Máthé

  2. Facultad de Farmacia y Bioquímica, Farmacognosia, Universidad de Buenos Aires, Buenos Aires, Argentina

    Arnaldo Bandoni

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Isla, M.I., Leal, M., Carrizo, S.L., Zampini, I.C. (2021). Baccharis tola Phil., B. boliviensis (Wedd.) Cabrera. In: Máthé, Á., Bandoni, A. (eds) Medicinal and Aromatic Plants of South America Vol. 2. Medicinal and Aromatic Plants of the World, vol 7. Springer, Cham. https://doi.org/10.1007/978-3-030-62818-5_6

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