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Biosynthesis of Natural Products in Plants by Fungal Endophytes with an Emphasis on Swainsonine

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Phytochemicals – Biosynthesis, Function and Application

Part of the book series: Recent Advances in Phytochemistry ((RAPT,volume 44))

Abstract

Plant natural products are frequently used as chemotaxonomic markers which are indicative of select members of a family, genus, and/or species. However, the erratic occurrence of some natural products raises questions about their biosynthetic origin and significance as chemotaxonomic markers. Recent research has shown that fungal endophytes associated with plants are a rich source of natural products. The objective of this review is to highlight natural products found in plants that are reported to be derived from fungal endophytes and, when appropriate, briefly comment on the plant-endophyte interaction. We will summarize current knowledge on alkaloids synthesized by Clavicipitaceae endophytes, then on other diverse secondary metabolites including taxol and camptothecin. Specifically, we will highlight the role that fungal endophytes play in the synthesis of the indolizidine alkaloid swainsonine and the interaction between host and endophyte.

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Authors and Affiliations

  1. Poisonous Plant Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 1150 E 1400 N, 84341, Logan, UT, United States

    Daniel Cook, Dale R. Gardner, James A. Pfister & Daniel Grum

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  1. Daniel Cook
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  2. Dale R. Gardner
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  3. James A. Pfister
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  4. Daniel Grum
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Correspondence to Daniel Cook .

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  1. Department of Botany, The University of British Columbia, Vancouver, British Columbia, Canada

    Reinhard Jetter

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Cook, D., Gardner, D., Pfister, J., Grum, D. (2014). Biosynthesis of Natural Products in Plants by Fungal Endophytes with an Emphasis on Swainsonine. In: Jetter, R. (eds) Phytochemicals – Biosynthesis, Function and Application. Recent Advances in Phytochemistry, vol 44. Springer, Cham. https://doi.org/10.1007/978-3-319-04045-5_2

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