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Therapeutic Potential of Mushroom Bioactive Nutraceuticals

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Biology, Cultivation and Applications of Mushrooms

Abstract

Considerable elucidations and intensive research attempted on the immense nutritional values and effective health augmenting properties of mushrooms are dynamically extending as per present day needs. Mushrooms have been acknowledged as the treasure trove of nutrients including high quality proteins, polysaccharides, triterpenes, polyunsaturated fatty acids, dietary fiber, sterols, secondary metabolites, mineral substances, and vitamins. These constituents play a significant role in significantly preventing and curing various health problems, ailments and dreaded diseases such as immunodeficiency, inflammation, cancer, hyperlipidemia, hypercholesterolemia, obesity, hypertension, fungal, bacterial, and viral infections. The present review article endeavors to provide the information and correlate the health effects with underlying biological mechanisms of mushroom nutraceuticals. It tends to be affirmed that augmentation of a dietary composition by inclusion of mushrooms possesses the potential of being a natural adjuvant for the alleviation of multiple chronic diseases.

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Abbreviations

AP-1:

Activator protein-1

CMP:

Coprinus comatus mycelium polysaccharide

DPPH:

2, 2-diphenyl-1-picrylhydrazyl

HIV :

Human immunodeficiency virus

IL:

Interleukin

MAPK :

Mitogen activated protein kinases

NADH:

Nicotinamide adenine dinucleotide hydrogen

NF-κB:

Nuclear factor kappa light chain enhancer of activated B cells

ROS:

Reactive oxygen species

TNF:

Tumor necrosis factor

TLR:

Toll like receptor

TRP:

Tyrosinase related protein

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Acknowledgements

We are grateful to the Head, Department of Botany (UGC-SAP II DRS II), University of Jammu, Jammu and Kashmir, for providing the laboratory facilities. The first author gratefully acknowledges the financial support from Council of Scientific and Industrial Research (CSIR), New Delhi.

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© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Altaf, U., Hashmi, S.A.J., Sharma, Y.P. (2022). Therapeutic Potential of Mushroom Bioactive Nutraceuticals. In: Arya, A., Rusevska, K. (eds) Biology, Cultivation and Applications of Mushrooms . Springer, Singapore. https://doi.org/10.1007/978-981-16-6257-7_12

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