Two new aspidosperma-type alkaloids, taberibogines C and D (1 and 2), along with three known ones (3–5), were isolated from the leaves of Tabernaemontana bovina. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and X-ray crystal diffraction. Alkaloids 1-2 exhibited moderate inhibitory effects on LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages.

中文翻译：

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来自 Tabernaemontana bovina 的新型 aspidosperma 型生物碱

从Tabernaemontana bovina的叶子中分离出两种新的 aspidosperma 型生物碱，taberibogines C 和 D（1和2 ），以及三种已知的（3-5 ）。通过广泛的光谱分析和 X 射线晶体衍射阐明了它们的结构，包括绝对构型。生物碱1-2在 RAW 264.7 巨噬细胞中对 LPS 诱导的一氧化氮 (NO) 产生具有中度抑制作用。